- Conditions
- Chronic Rhinosinusitis (Diagnosis), Cystic Fibrosis
- Interventions
- Not listed
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Stanford, California • Aurora, Colorado + 6 more
Search Results
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Showing 25–48
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- Conditions
- Chronic Rhinosinusitis (Diagnosis)
- Interventions
- PROPEL Contour Sinus Implant, Balloon Sinus Dilation Alone
- Device · Procedure
- Lead sponsor
- Intersect ENT
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 14
- States / cities
- Sacramento, California • San Francisco, California • Boca Raton, Florida + 10 more
- Conditions
- Ethmoid Sinusitis
- Interventions
- Sinopsys Lacrimal Stent
- Device
- Lead sponsor
- Sinopsys Surgical
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 3
- States / cities
- Stanford, California • Greeley, Colorado • Louisville, Kentucky
- Conditions
- Rhinosinusitis
- Interventions
- Observational study
- Other
- Lead sponsor
- Monell Chemical Senses Center
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 3
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Nasal Polyps
- Interventions
- Depemokimab (GSK3511294), Placebo
- Biological · Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 264 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 14
- States / cities
- Tucson, Arizona • Roseville, California • New Haven, Connecticut + 11 more
- Conditions
- Nasal Polyposis, Eosinophilic Chronic Rhinosinusitis
- Interventions
- Benralizumab 30 mg, Matched placebo
- Biological
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 295 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 15
- States / cities
- Huntington Beach, California • Grand Junction, Colorado • Gainesville, Florida + 12 more
- Conditions
- Sinusitis, Cystic Fibrosis
- Interventions
- Pulmozyme single use ampule, placebo
- Drug
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 12 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Chronic Rhinosinusitis (Diagnosis)
- Interventions
- Lactobacillus sakei proBio65, Isotonic Saline Solution
- Drug · Other
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Rhinosinusitis (Diagnosis)
- Interventions
- Ivacaftor, standard of care treatment
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Sinusitis
- Interventions
- Amoxicillin-Potassium Clavulanate, Placebo
- Drug
- Lead sponsor
- Massachusetts Eye and Ear Infirmary
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 134 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Rhinosinusitis
- Interventions
- Checklist introduction / Pause
- Behavioral
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Sinusitis
- Interventions
- XprESS device and PathAssist confirmation tools
- Device
- Lead sponsor
- Entellus Medical, Inc.
- Industry
- Eligibility
- 2 Years to 21 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 4
- States / cities
- Phoenix, Arizona • Salem, Oregon • Charleston, South Carolina + 1 more
- Conditions
- Sinusitis
- Interventions
- Balloon sinus dilation, Medical Management
- Device · Drug
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 19 Years and older
- Enrollment
- 198 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 20
- States / cities
- Denver, Colorado • Miami, Florida • Tampa, Florida + 17 more
- Conditions
- Endoscopic Sinus Surgery, Chronic Rhinosinusitis
- Interventions
- Not listed
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Sinusitis, Chronic Rhinosinusitis
- Interventions
- Ethmoid Sinus Spacer
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Savannah, Georgia
- Conditions
- Sinusitis, Nasal Polyps
- Interventions
- Verapamil Hydrochloride Intranasal
- Drug
- Lead sponsor
- Benjamin Bleier
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Rhinosinusitis With Nasal Polyps
- Interventions
- Experimental: Tezepelumab, Placebo, Mometasone furoate or equivalent intranasal corticosteroid
- Biological · Other · Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 416 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Bakersfield, California • Newport Beach, California + 18 more
- Conditions
- Nasal Polyps, Chronic Rhinosinusitis
- Interventions
- Omalizumab, Placebo
- Drug
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 127 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 16
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Rancho Cordova, California + 13 more
- Conditions
- Sinusitis
- Interventions
- Zithromax™ (azithromycin) 500mg tablets, Endoscopic Sinus Surgery, Blood sampling for hematology, Blood sampling for plasma chemistry profile, Serum pregnancy test (for women of child-bearing potential)
- Drug · Procedure
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 18
- States / cities
- Alabaster, Alabama • Birmingham, Alabama • Hoover, Alabama + 11 more
- Conditions
- Chronic Rhinosinusitis (Diagnosis)
- Interventions
- Comparison of medication administration for pain control
- Other
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Sinusitis, Rhinosinusitis, Nasal Polyps
- Interventions
- Prednisone
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2019
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Nasal Polyps, Aspirin-exacerbated Respiratory Disease
- Interventions
- Non-Interventional
- Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Nasal Polyps, Sinusitis, Chronic Disease
- Interventions
- Dupilumab
- Biological
- Lead sponsor
- Madigan Army Medical Center
- Federal
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Tacoma, Washington
- Conditions
- Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)
- Interventions
- LYR-220 Design 1 (Part 1 only), LYR-220 Design 2 (Part 1 and Part 2), Bilateral sham procedure control (Part 2)
- Drug
- Lead sponsor
- Lyra Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 22
- States / cities
- Carlsbad, California • La Mesa, California • Roseville, California + 18 more