- Conditions
- Nicotine Dependence
- Interventions
- Nicotine patch, ENDS, Placebo patch, Placebo ENDS
- Drug · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Sedentary Lifestyle, Cigarette Smoking
- Interventions
- PA+ Smoking Cessation (LMPA), Standard Care Smoking Counseling (SCC)
- Behavioral
- Lead sponsor
- Temple University
- Other
- Eligibility
- 18 Years to 59 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Nicotine Use Disorder
- Interventions
- Nicotine, Flavor
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Smoking
- Interventions
- Quit smoking, Nicotine patch, Placebo Patch
- Behavioral · Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Electronic Cigarette Use
- Interventions
- Tobacco product administration and assessment, own brand cigarettes, Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine, Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine
- Other
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Smoking, Smoking Cessation
- Interventions
- Coordinated Care, Usual Care
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 633 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Tobacco Use
- Interventions
- Normal Nicotine Content Vape with all flavor e-liquids, Normal nicotine content vape with tobacco e-liquids, Low nicotine content vape with all flavor e-liquids, Low nicotine content vape with tobacco e-liquids
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Cigarette Smoking
- Interventions
- High-ventilated cigarette alone, Low-ventilated cigarette alone, High- and low-ventilated cigarette with high-ventilated cigarettes increasing in price, Low- and high-ventilated cigarette with high-ventilated cigarettes increasing in price, Usual, high- and low-ventilated cigarette with usual cigarettes increasing in price.
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 89 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Cardiovascular Disease, Insulin Resistance
- Interventions
- Smoking cessation
- Behavioral
- Lead sponsor
- Charles Drew University of Medicine and Science
- Other
- Eligibility
- 25 Years to 70 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- HIV, Emphysema, HIV Infections
- Interventions
- Not listed
- Lead sponsor
- Philip Diaz
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 365 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Nicotine Dependence
- Interventions
- zonisamide, placebo
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Cigarette Smoking
- Interventions
- Contingency Management, Standard of Care
- Behavioral · Other
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- New Britain, Connecticut
- Conditions
- Tobacco Dependence
- Interventions
- Nicotine free cigarettes, Extra-low nicotine cigarettes, Nicotine Lozenge
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
- Interventions
- Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Smoking, Cigarette
- Interventions
- Package standardization
- Behavioral
- Lead sponsor
- RAND
- Other
- Eligibility
- 21 Years to 34 Years
- Enrollment
- 433 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Cigarette Smoking
- Interventions
- Best Practices, Financial Incentives, Nicotine Replacement Therapy
- Behavioral · Drug
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 198 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Chronic Pain, Tobacco Use, Opioid Substitution Treatment
- Interventions
- Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Smoking, Smoking Cessation, Craving, Addiction, Addiction Nicotine, Nicotine Dependence, Cigarette Smoking
- Interventions
- Real TBS to the vmPFC, Sham cTBS to the vmPFC
- Device
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Tobacco Smoking
- Interventions
- Nicotine Patch, E-cigarette
- Drug
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Smoking Cessation, Cigarette Smoking
- Interventions
- Healing Within: Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence
- Behavioral
- Lead sponsor
- Black Hills Center for American Indian Health
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Rapid City, South Dakota
- Conditions
- Electronic Cigarette Use
- Interventions
- RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Subject Usual Brand ENDS
- Other
- Lead sponsor
- Cheerain HK Limited
- Industry
- Eligibility
- 22 Years to 59 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Cypress, California • Overland Park, Kansas
- Conditions
- Nicotine Dependence, Cigarettes
- Interventions
- AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 14 Years to 20 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Smoking, Tobacco Use
- Interventions
- Low Power, High Power, Low Concentration, High Concentration
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Smoking, Cigarette, Alveolar Bone Grafting, Wound Healing, Bone Healing, Tooth Extraction Site Healing
- Interventions
- observational study
- Other
- Lead sponsor
- Marquette University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin