Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 7, 2026, 1:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Circadian Disruption Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Circadian Rhythm Disruption Effects on Smoke Inhalation

NCT04955431
View directory record Official record
Conditions
Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
Interventions
Sleep Restriction, Normal Sleep
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Jun 7, 2026, 1:30 PM EDT
Recruiting Not applicable Interventional

PICU-related Sleep and Circadian Dysregulation Pilot Study

NCT06505447
View directory record Official record
Conditions
Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, Only
Interventions
Daytime light exposure, Daytime restricted feeding
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
3 Years to 6 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Circadian OS Technology on Melatonin Suppression

NCT07095270
View directory record Official record
Conditions
Circadian Disruption
Interventions
Circadian OS software
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
30 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Jun 7, 2026, 1:30 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cardiometabolic Risk of Shiftwork

NCT01264913
View directory record Official record
Conditions
Sleep Deprivation, Circadian Dysregulation, Shift-Work Sleep Disorder
Interventions
sleep extension & circadian alignment
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2016 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Music, Sleep and Dementia Study

NCT04157244
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions
Tailored music listening intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 110 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional

Optimized Sleep After Brain Injury: Sleep Hygiene Intervention After Traumatic Brain Injury

NCT02838082
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Sleep Hygiene Protocol, Standard of Care
Behavioral
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Jun 7, 2026, 1:30 PM EDT
Recruiting Not applicable Interventional

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

NCT04737200
View directory record Official record
Conditions
Feeding Patterns, Sleep, Glucose Intolerance
Interventions
Time-of-day of enteral nutrition provision (daytime first), Time-of-day of enteral nutrition provision (nighttime first)
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jun 7, 2026, 1:30 PM EDT
Active, not recruiting No phase listed Observational

Circadian Rhythm Disruption in the Hospital Intensive Care Environment

NCT05828680
View directory record Official record
Conditions
Surgery, Cardiovascular Diseases
Interventions
Observation
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Timeline
2023 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jun 7, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Sleep Disruption on the Menstrual Cycle

NCT00456222
View directory record Official record
Conditions
Sleep, Circadian Rhythm, Menstrual Cycle
Interventions
Disrupting or changing the timing or the duration of sleep
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2009 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

NCT02171273
View directory record Official record
Conditions
Aging, Sleep Restriction, Circadian Disruption
Interventions
Circadian Disruption, Sleep Restriction, Control
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jun 7, 2026, 1:30 PM EDT
Completed No phase listed Observational

Study of Sleep and Delirium in the Intensive Care Unit (ICU)

NCT01280097
View directory record Official record
Conditions
Delirium, Sleep Disorders, Circadian Rhythm
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2015 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Simulated Dawn Med Students

NCT02088593
View directory record Official record
Conditions
Depression, Anxiety, Fatigue, Sleepiness, Sleep Disruption
Interventions
Simulated Dawn Light Box, Sleep Hygiene instructions
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jun 7, 2026, 1:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Microbiome and Resilience to Sleep and Circadian Disruption

NCT03747367
View directory record Official record
Conditions
Sleep Deprivation, Circadian Dysregulation, Stress
Interventions
Insufficient Sleep
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Jun 7, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Night Float Call on Sleep and Activity Patterns Among Anesthesia Residents

NCT05043038
View directory record Official record
Conditions
Sleep Disorder, Shift Work, Fatigue, Sleep Disturbance
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Jun 7, 2026, 1:30 PM EDT
Active, not recruiting Not applicable Interventional

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

NCT07203196
View directory record Official record
Conditions
Aging, Healthy, Blood Sugar; High, Blood Sugar (Glucose) Control, Time Restricted Eating, Circadian Dysregulation
Interventions
Circadian Rhythm Optimization
Behavioral
Lead sponsor
Salk Institute for Biological Studies
Other
Eligibility
50 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jun 7, 2026, 1:30 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 7, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Disruption Induced Impairments in Bone Formation

NCT03733483
View directory record Official record
Conditions
Healthy
Interventions
Sleep Deprivation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 65 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jun 7, 2026, 1:30 PM EDT
Recruiting Phase 4 Interventional

Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)

NCT01406691
View directory record Official record
Conditions
Delayed Sleep Phase Disorder
Interventions
Flashes
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 19 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jun 7, 2026, 1:30 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Light Exposure to Treat Sleep Disruption in Older People

NCT00427323
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
Interventions
light exposure
Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2009 · Synced Jun 7, 2026, 1:30 PM EDT