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Conditions: Acute Kidney Injury, Abdominal Compartment Syndrome, Intraabdominal Hypertension, Cardiovascular Surgery
Interventions: Accuryn Monitoring System; Device
Lead sponsor: Potrero Medical; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Chronic Exertional Compartment Syndrome
Interventions: Supervised Gait Retraining, Home Based Gait Retraining, Saline Injection, Botulinum Toxin Injection; Behavioral · Drug
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years to 50 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 4
States / cities: Bethesda, Maryland • Fort Bragg, North Carolina • Killeen, Texas + 1 more

Conditions: Anterior Knee Pain Syndrome
Interventions: observation of the behavior of the infrapatellar plica; Procedure
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Wounds and Injuries, Compartment Syndrome
Interventions: DermaClose fasciotomy closure, Vessel loop; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: HIV Infections
Interventions: Single dose of Genvoya® and a single 800 mg dose of Darunavir®; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 49 Years · Male only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obesity, Intra-Abdominal Hypertension
Interventions: Respiratory mechanics assessment; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hernia Repair With Compartment Syndrome
Interventions: Flex HD, Strattice; Device
Lead sponsor: John Roth; Other
Eligibility: 18 Years to 85 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Compartment Syndrome of Leg
Interventions: AbobotulinumtoxinA, Placebo; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Atlanta, Georgia • Brookhaven, Georgia

Conditions: Ventral Hernia
Interventions: Components separation hernia repair; Procedure
Lead sponsor: Northwestern University; Other
Eligibility: Not listed
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Compartment Syndrome
Interventions: Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal; Device
Lead sponsor: Twin Star Medical, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 13
States / cities: Orange, California • San Francisco, California • Denver, Colorado + 9 more

Conditions: Compartment Syndromes
Interventions: Percutaneous catheter drainage; Procedure
Lead sponsor: Orlando Regional Medical Center; Other
Eligibility: 15 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Intra-Abdominal Hypertension
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 2 Months
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Chronic Exertional Compartment Syndrome
Interventions: Botulinum toxin injections for chronic compartment syndrome, surgical fasciotomy for chronic compartment syndrome; Drug · Procedure
Lead sponsor: 375th Medical Group, Scott Air Force Base; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Scott Air Force Base, Illinois

Conditions: Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Interventions: Accuryn Monitoring System; Device
Lead sponsor: Potrero Medical; Industry
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 9
States / cities: Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 6 more

Conditions: Acute Compartment Syndrome
Interventions: Shaving; Other
Lead sponsor: J&M Shuler; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Compartment Syndromes
Interventions: Near infrared spectroscopy (NIRS); Diagnostic Test
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Acute Compartment Syndrome, Fracture, Bone, Tibial Fractures
Interventions: Tissue Ultrafiltration Catheters; Device
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 4
States / cities: Baltimore, Maryland • Minneapolis, Minnesota • Charlotte, North Carolina + 1 more

Conditions: HIV Infections
Interventions: Truvada, Genvoya; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 49 Years · Male only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Compartment Syndrome
Interventions: Magellan®; Device
Lead sponsor: Arteriocyte, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Acute Compartment Syndrome
Interventions: Near infrared spectroscopy (NIRS); Device
Lead sponsor: J&M Shuler; Industry
Eligibility: 15 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Intra-Abdominal Hypertension, Inguinal Hernia
Interventions: Accuryn Monitoring System; Device
Lead sponsor: Antonios Likourezos; Other
Eligibility: 18 Years to 65 Years
Enrollment: 21 participants
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Compartment Syndrome
Interventions: Tissue ultrafiltration; Device
Lead sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); NIH
Eligibility: 14 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tibial Shaft Fracture, Tibial Plateau Fracture
Interventions: Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome; Procedure
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 90 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome, Hernia Surgery, Hernia, Hernia Incisional
Interventions: OnabotulinumtoxinA Injection, Saline (placebo) Injection, OnabotulinumtoxinA, 0.9 % Normal Saline, Open Ventral Hernia Repair; Procedure · Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Cleveland, Ohio

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Physiologic Signals and Signatures With the Accuryn Monitoring System (The Accuryn Registry)

Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)

In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee

Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander

Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis.

Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients

Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases

Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A

Prospective Study of Ventral Hernia Repair

Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg

Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal Pressure

Intra-Abdominal Hypertension in Neonatal Intensive Care Patients

Botulinum for Chronic Exertional Compartment Syndrome

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured Subjects

Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion?

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities

Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield Trauma

The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome

Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output

Management of Compartment Syndrome With Ultrafiltration

Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome

Preoperative BOTOX® Injection for Large Ventral Hernia Repair