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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Compartment Syndrome Clear all
Recruiting Not applicable Interventional

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

NCT06876896
View directory record Official record
Conditions
Intra-Abdominal Hypertension
Interventions
Accuryn Foley catheter device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 3 Interventional

Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal Pressure

NCT01230255
View directory record Official record
Conditions
Compartment Syndromes
Interventions
Percutaneous catheter drainage
Procedure
Lead sponsor
Orlando Regional Medical Center
Other
Eligibility
15 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2010 · Synced Jul 22, 2026, 4:56 AM EDT
Enrolling by invitation Not applicable Interventional

Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome

NCT05521958
View directory record Official record
Conditions
Tibial Shaft Fracture, Tibial Plateau Fracture
Interventions
Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 4:56 AM EDT
Recruiting No phase listed Observational

Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

NCT04669548
View directory record Official record
Conditions
Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Interventions
Accuryn Monitoring System
Device
Lead sponsor
Potrero Medical
Industry
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
9
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Jul 22, 2026, 4:56 AM EDT
Terminated Phase 4 Interventional Results available

Botox for the Treatment of Recurrent Chronic Exertional Compartment Syndrome

NCT05006417
View directory record Official record
Conditions
Compartment Syndrome of Leg
Interventions
Botox
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jul 22, 2026, 4:56 AM EDT
Recruiting Not applicable Interventional

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients

NCT05830721
View directory record Official record
Conditions
Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication, Limb Ischemia, Limb Ischemia, Critical
Interventions
MY01 + Standard of Care, 14-Gauge Slit Catheter + Standard of Care, Standard of Care
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Not listed No phase listed Observational

The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome

NCT01171638
View directory record Official record
Conditions
Acute Compartment Syndrome
Interventions
Near infrared spectroscopy (NIRS)
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
15 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2011 · Synced Jul 22, 2026, 4:56 AM EDT
Active, not recruiting Phase 1 Interventional

BM-MNCs for Lower Extremity Compartment Syndrome Injury

NCT03880656
View directory record Official record
Conditions
Compartment Syndrome Traumatic Lower Extremity
Interventions
Intramuscular administration of autologous BM-MNCs
Biological
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Not yet recruiting Not applicable Interventional

MY01 Pressure Monitoring in Adolescent Tibia Fractures

NCT07674043
View directory record Official record
Conditions
Proximal Tibia Fracture, Tibial Shaft Fracture, Acute Compartment Syndrome
Interventions
Continuous Compartmental Pressure Monitor
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 22, 2026, 4:56 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Muscle Oxygenation and Skin Pigmentation

NCT00747162
View directory record Official record
Conditions
Muscle Oxygenation, Skin Pigmentation
Interventions
Measure of muscle oxygenation, Skin pigmentation determination
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 26, 2013 · Synced Jul 22, 2026, 4:56 AM EDT
Not listed Not applicable Interventional

Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

NCT04671173
View directory record Official record
Conditions
Acute Compartment Syndrome
Interventions
Measurement of the Intra-Compartmental Pressure with the MY01 device
Device
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Diagnosing Compartment Syndrome With SHAPE vs Elastography

NCT05247541
View directory record Official record
Conditions
Chronic Exertional Compartment Syndrome
Interventions
Definity
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A

NCT05466539
View directory record Official record
Conditions
Compartment Syndrome of Leg
Interventions
AbobotulinumtoxinA, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Atlanta, Georgia • Brookhaven, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases

NCT01597128
View directory record Official record
Conditions
Hernia Repair With Compartment Syndrome
Interventions
Flex HD, Strattice
Device
Lead sponsor
John Roth
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Jul 22, 2026, 4:56 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg

NCT00681616
View directory record Official record
Conditions
Compartment Syndrome
Interventions
Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
Device
Lead sponsor
Twin Star Medical, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
13
States / cities
Orange, California • San Francisco, California • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2009 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 1 Interventional Results available

Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities

NCT02985996
View directory record Official record
Conditions
HIV Infections
Interventions
Truvada, Genvoya
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Jul 22, 2026, 4:56 AM EDT
Recruiting No phase listed Observational

Can Near-Infrared Spectroscopy (NIRS) or Intramuscular Glucose Levels Detect Impaired Leg Compartment' Perfusion?

NCT06512870
View directory record Official record
Conditions
Compartment Syndromes
Interventions
Near infrared spectroscopy (NIRS)
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Jul 22, 2026, 4:56 AM EDT
Completed No phase listed Observational

Assessment of Near Infrared Spectroscopy as a Diagnostic Tool in Acute Compartment Syndrome

NCT01077934
View directory record Official record
Conditions
Compartment Syndrome
Interventions
near-infrared spectroscopy
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
13 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 1 Interventional

Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis.

NCT03472963
View directory record Official record
Conditions
HIV Infections
Interventions
Single dose of Genvoya® and a single 800 mg dose of Darunavir®
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vasopressin in Intraabdominal Pressure Elevation

NCT03707054
View directory record Official record
Conditions
Intracranial Pressure Increase, Abdominal Compartment Syndrome
Interventions
Study Arm
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 72 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 22, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured Subjects

NCT01284023
View directory record Official record
Conditions
Acute Compartment Syndrome
Interventions
Shaving
Other
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Jul 22, 2026, 4:56 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers

NCT04113954
View directory record Official record
Conditions
Compartment Syndrome of Leg, Healthy
Interventions
Mepivacaine Injection
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Jul 22, 2026, 4:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Study of Ventral Hernia Repair

NCT00894582
View directory record Official record
Conditions
Ventral Hernia
Interventions
Components separation hernia repair
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2009 · Synced Jul 22, 2026, 4:56 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Botulinum for Chronic Exertional Compartment Syndrome

NCT03339921
View directory record Official record
Conditions
Chronic Exertional Compartment Syndrome
Interventions
Botulinum toxin injections for chronic compartment syndrome, surgical fasciotomy for chronic compartment syndrome
Drug · Procedure
Lead sponsor
375th Medical Group, Scott Air Force Base
Federal
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Jul 22, 2026, 4:56 AM EDT