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ClinicalTrials.gov public records Last synced Oct 15, 2026, 4:07 PM EDT

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Showing 577–600 of 634 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Complications of Prematurity Clear all
Completed Phase 2Phase 3 Interventional Results available

17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies

NCT00163020
View directory record Official record
Conditions
Preterm Birth
Interventions
17-alpha-hydroxyprogesterone caproate injectable, Placebo
Drug
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
18
States / cities
Phoenix, Arizona • Tucson, Arizona • Laguna Hills, California + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional Results available

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

NCT01029353
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions
Laparotomy, Drainage
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Weeks
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
22
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional

Effect of Vitamin D in Diets of Preterm Infants

NCT01698840
View directory record Official record
Conditions
Premature Infants
Interventions
Vitamin D, Placebo
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

NIRS Monitoring in Premature Infants

NCT02601339
View directory record Official record
Conditions
Hemorrhage, Premature Infants, Newborn, Hydrocephalus
Interventions
ETV/CPC
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Months to 12 Months
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional Results available

Sustained Aeration of Infant Lungs Trial

NCT02139800
View directory record Official record
Conditions
Preterm Birth, Extreme Prematurity
Interventions
Sustained Inflation, Standard of Care
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
23 Weeks to 26 Weeks
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
9
States / cities
Loma Linda, California • Sacramento, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 15, 2026, 4:07 PM EDT
Completed No phase listed Observational

Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis

NCT00059449
View directory record Official record
Conditions
Necrotizing Enterocolitis, Premature Birth
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
Up to 72 Hours
Enrollment
372 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
3
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Oct 15, 2026, 4:07 PM EDT
Completed No phase listed Observational

US and Neurodevelopmental Outcomes in the Neonatal Intensive Care Unit (NICU)

NCT05071508
View directory record Official record
Conditions
Premature Birth
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
25 Weeks to 34 Weeks
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 15, 2026, 4:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)

NCT06555315
View directory record Official record
Conditions
Very Low Birth Weight Infant, Premature Infants, Anemia of Prematurity, Iron Deficiency, Anaemia in Children, Extremely Low Birth Weight
Interventions
6 mg/kg of oral iron as ferrous sulfate administered every other day., 6 mg/kg of oral iron as ferrous sulfate administered every day.
Dietary Supplement
Lead sponsor
CHRISTUS Health
Other
Eligibility
26 Weeks to 32 Weeks
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Oct 15, 2026, 4:07 PM EDT
Active, not recruiting No phase listed Observational

Dilapan-S®: A Multicenter US E-registry

NCT04451109
View directory record Official record
Conditions
Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios, Gestational Diabetes, High Blood Pressure in Pregnancy
Interventions
Dilapan-S
Device
Lead sponsor
Medicem Technology s.r.o.
Other
Eligibility
18 Years and older · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 15, 2026, 4:07 PM EDT
Suspended Not applicable Interventional

The Milk, Growth and Microbiota Study

NCT03220282
View directory record Official record
Conditions
Preterm Infant, Growth Delay, Microbial Colonization, Breastfeeding, Breast Milk Substitute Intolerance
Interventions
Donor milk, Preterm infant formula
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Hour to 96 Hours
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Not listed Not applicable Interventional

Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention

NCT03518736
View directory record Official record
Conditions
Preterm Infant, Cerebral Palsy
Interventions
Supporting Play Exploration and Developmental Intervention (SPEEDI)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Up to 6 Months
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 15, 2026, 4:07 PM EDT
Withdrawn Phase 2 Interventional

Prediction of NEC With Urinary iFABP

NCT01805206
View directory record Official record
Conditions
Prematurity, Necrotizing Enterocolitis
Interventions
Assessment of urinary iFABP, Administration of enteral feedings
Other
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 2 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Oct 15, 2026, 4:07 PM EDT
Completed No phase listed Observational

Biomarkers Associated With Spontaneous Preterm Birth Less Than 32 Wks Gestation

NCT02317315
View directory record Official record
Conditions
Preterm Labor, Preterm Birth
Interventions
Not listed
Lead sponsor
Ranjith Kamity, MD
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3

NCT03333174
View directory record Official record
Conditions
Infant,Premature
Interventions
Cardiorespiratory monitoring
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 98 Days
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Oct 15, 2026, 4:07 PM EDT
Active, not recruiting Not applicable Interventional

ViDES Trial (Vitamin D Extra Supplementation)

NCT05459298
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Placebo, 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
Dietary Supplement · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Hours to 96 Hours
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

NCT04278404
View directory record Official record
Conditions
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
Interventions
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
Drug
Lead sponsor
Duke University
Other
Eligibility
0 Years to 20 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
49
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 40 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional

Timing of Inguinal Hernia Repair in Premature Infants

NCT01678638
View directory record Official record
Conditions
Inguinal Hernia, Premature Birth of Newborn
Interventions
IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 37 Weeks
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
40
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 15, 2026, 4:07 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Gut Microbiome (MGM) Study of Diet, the Gut Microbiome and Preterm Birth

NCT02560246
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 15, 2026, 4:07 PM EDT
Recruiting Not applicable Interventional

The Periviable GOALS Decision Support Tool

NCT05264779
View directory record Official record
Conditions
Pregnancy Preterm, Premature Birth, Pregnancy Complications, Obstetric Labor, Premature, Obstetric Labor Complications
Interventions
Periviable GOALS DST
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
12
States / cities
San Diego, California • San Francisco, California • New Haven, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Phase 2 Interventional Results available

GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients

NCT00429494
View directory record Official record
Conditions
Amenorrhea, Premature Ovarian Failure, Ovarian Function Insufficiency
Interventions
Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation
Drug · Behavioral · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Up to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prematurity Education in High Risk Pregnancies

NCT03772080
View directory record Official record
Conditions
Prematurity, High Risk Pregnancy
Interventions
Early counseling of prematurity in high-risk pregnancies.
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional Results available

Use of NIRS in Preterm Population Born at Altitude

NCT04639583
View directory record Official record
Conditions
Prematurity; Extreme
Interventions
Near-infrared spectroscopy (NIRS) utilization
Device
Lead sponsor
University of New Mexico
Other
Eligibility
0 Hours to 24 Hours
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 15, 2026, 4:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study for Development of an Early Test for Ovarian Failure

NCT00006156
View directory record Official record
Conditions
Healthy, Premature Ovarian Failure
Interventions
Control, Drug: FSH
Other · Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 16, 2013 · Synced Oct 15, 2026, 4:07 PM EDT
Not listed Phase 1Phase 2 Interventional

Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO

NCT02851472
View directory record Official record
Conditions
Anemia
Interventions
Inhaled Nitric Oxide, Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
2 Weeks and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Springfield, Massachusetts • Stony Brook, New York • Valhalla, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 15, 2026, 4:07 PM EDT