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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:56 PM EDT

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Showing 1–24 of 436 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Compression Clear all
Completed Phase 1 Interventional

Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

NCT02429557
View directory record Official record
Conditions
Orthostatic Hypotension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions
Abdominal compression, Sham abdominal compression, Placebo pill, midodrine
Other · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Results available

The CONTRoL Trial: Cryotherapy vs. cOmpression Neuropathy TRiaL

NCT03873272
View directory record Official record
Conditions
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Interventions
Cryotherapy, Compression Therapy, Loose glove/sock
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 99 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 23, 2026, 3:56 PM EDT
Not listed No phase listed Observational

Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis

NCT04784156
View directory record Official record
Conditions
Foot Arthritis
Interventions
Subtalar (Talocalcaneal) Arthrodesis, DynaNail Mini
Procedure · Device
Lead sponsor
MedShape, Inc
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 23, 2026, 3:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Design Validation Hemodynamic Study of New Kendall SCD SmartFlow Compression System

NCT05945186
View directory record Official record
Conditions
Hemodynamics
Interventions
Intermittent Pneumatic Compression (IPC)(Kendall SCD SmartFlow™ compression system with Cardinal Health Element compression sleeves)
Device
Lead sponsor
Cardinal Health
Industry
Eligibility
18 Years to 89 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2023 · Synced Oct 23, 2026, 3:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

NCT07159269
View directory record Official record
Conditions
Cardiovascular Disease Acute, Emergency Department Patient, Heart Failure Acute, Pulmonary Embolism (Diagnosis), Point of Care Ultrasound (POCUS), Cardiac Tamponade, Pericardial Effusion, Diagnostic Imaging, Medical Training, Implementation Science
Interventions
Cardiac point-of-care ultrasound (POCUS) training and clinical pathway
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Phase 2 Interventional

Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

NCT03111186
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Dupuytren Contracture, Trigger Digit, Ganglion Cysts, De Quervain Disease
Interventions
Oxycodone Hcl 5Mg, Ibuprofen 400 mg, Acetaminophen 650 mg
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cost Information on Carpal Tunnel Syndrome Treatment Decisions

NCT03880812
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Societal cost
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Results available

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

NCT05405218
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS, Carpal Tunnel
Interventions
CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Sonora, California • Fort Walton Beach, Florida • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 23, 2026, 3:56 PM EDT
Recruiting Phase 4 Interventional

Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers

NCT06754735
View directory record Official record
Conditions
Venous Leg Ulcer (VLU)
Interventions
Topical Wound Oxygen Therapy, Sham Control Topical Wound Oxygen
Device
Lead sponsor
AOTI Ltd.
Industry
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional

Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.

NCT04804098
View directory record Official record
Conditions
Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury, Eustachian Tube Dysfunction, Middle Ear; Injury, Middle Ear Barotrauma
Interventions
Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
1,553 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Carpal Tunnel Syndrome With Dynamic Splinting

NCT00558116
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Dynamic splinting
Device
Lead sponsor
Advanced Centers for Orthopaedic Surgery and Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2008 · Synced Oct 23, 2026, 3:56 PM EDT
Recruiting No phase listed Observational

A Real-World Registry of Chronic Wounds and Ulcers

NCT02280733
View directory record Official record
Conditions
Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions
Usual care
Other
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
300,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Phase 3 Interventional Results available

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

NCT01345019
View directory record Official record
Conditions
Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
Interventions
Denosumab, Zoledronic acid, Placebo to Denosumab, Placebo to zoledronic acid, Denosumab (for the open-label treatment phase)
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
1,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
79
States / cities
Tucson, Arizona • Fayetteville, Arkansas • Anaheim, California + 67 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 23, 2026, 3:56 PM EDT
Enrolling by invitation Not applicable Interventional

Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

NCT06837870
View directory record Official record
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lower Limb Compression Prevents Hypotension After Epidural in Labor

NCT04750486
View directory record Official record
Conditions
Labor Pain, Maternal Hypotension
Interventions
Sequential compression devices
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional

Evaluation of Bilayered Cellular Matrix (OrCel) for the Treatment of Venous Ulcers

NCT00270946
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Stasis Ulcer
Interventions
Bilayered Cellular Matrix (OrCel)
Device
Lead sponsor
Ortec International
Industry
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 29, 2005 · Synced Oct 23, 2026, 3:56 PM EDT
Not listed No phase listed Observational

Synovial Fluid Biomarkers Pre and Post Hymovis Knee Injection

NCT04093232
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hymovis
Drug
Lead sponsor
National Jewish Health
Other
Eligibility
21 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Oct 23, 2026, 3:56 PM EDT
Active, not recruiting Not applicable Interventional

STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures

NCT04835428
View directory record Official record
Conditions
Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
Interventions
Treatment Group: AGN1 LOEP SV Kit, Control Group: PMMA bone cement
Device
Lead sponsor
AgNovos Healthcare, LLC
Industry
Eligibility
50 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
12
States / cities
Birmingham, Alabama • Mesa, Arizona • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Results available

Intermittent Pneumatic Compression to Improve Revascularization Outcome

NCT04250675
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Intermittent pneumatic leg compressions, Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

NCT05535257
View directory record Official record
Conditions
Upper Extremity Weakness, Stroke
Interventions
Sequential Compression Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Saint Johns, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 23, 2026, 3:56 PM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2010 · Synced Oct 23, 2026, 3:56 PM EDT
Terminated Not applicable Interventional Results available

Clinical Trial Evaluating Acutrak Headless Compression Screw Fixation of Medial Malleolus Fractures

NCT03061279
View directory record Official record
Conditions
Medial Malleolus Fractures
Interventions
Fixation by Acutrak headless screw, Fixation by headed screws, plates, and or wires
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
3
States / cities
Palo Alto, California • Sacramento, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 23, 2026, 3:56 PM EDT
Recruiting Not applicable Interventional

Cold and Compression After Rotator Cuff Repair (RCR)

NCT07516327
View directory record Official record
Conditions
High-grade Partial or Full Thickness Rotator Cuff Tears
Interventions
SOC (Standard of care), Cold and Compression
Other · Device
Lead sponsor
Ochsner Health System
Other
Eligibility
35 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Kenner, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 3:56 PM EDT
Completed No phase listed Observational

Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies

NCT04737239
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Corticosteroid injections for CTS treatment
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 23, 2026, 3:56 PM EDT