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ClinicalTrials.gov public records Last synced Oct 25, 2026, 3:35 PM EDT

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Showing 121–144 of 370 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Conduction Defects Clear all
Completed No phase listed Observational

Medtronic Genetic Arrhythmia Markers for Early Detection (GAME Study)

NCT00664807
View directory record Official record
Conditions
Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation, Sick Sinus Syndrome
Interventions
Not listed
Lead sponsor
Medtronic Corporate Technologies and New Ventures
Industry
Eligibility
40 Years and older
Enrollment
1,023 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2009 · Synced Oct 25, 2026, 3:35 PM EDT
Withdrawn Early Phase 1 Interventional

Comparison of Ventricular Tachycardia Ablation Strategies in Patients With Ischemic Cardiomyopathy

NCT04512911
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Endocardial ablation, Endocardial- Epicardial ablation, Antiarrhythmic medications
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional

Non-invasive Vagal Stimulation for Frequent Premature Ventricular Complexes

NCT05341544
View directory record Official record
Conditions
Premature Ventricular Contraction
Interventions
Parasym device, Sham device
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
New York, New York • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Phase 3 Interventional Results available

AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation

NCT00560885
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
9
States / cities
Sacramento, California • Indianapolis, Indiana • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2013 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional Results available

Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF)

NCT00267098
View directory record Official record
Conditions
Atrioventricular Block, Heart Diseases
Interventions
Cardiac Resynchronization Therapy (CRT)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
918 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
51
States / cities
Anchorage, Alaska • Peoria, Arizona • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Dobutamine on the Cardiac Conduction System

NCT04249258
View directory record Official record
Conditions
Arrhythmias, Cardiac
Interventions
Dobutamine
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 25, 2026, 3:35 PM EDT
Withdrawn Phase 3 Interventional

Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions

NCT06110364
View directory record Official record
Conditions
Premature Ventricular Contraction
Interventions
Low-Level Tragus Stimulation, Heart Rate Variability- Biofeedback, Conventional Medical Therapy
Device · Behavioral · Other
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 25, 2026, 3:35 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Acute Salt Handling in Orthostatic Intolerance

NCT00581633
View directory record Official record
Conditions
Postural Tachycardia Syndrome, Orthostatic Tachycardia, Orthostatic Intolerance
Interventions
normal saline (0.9%)
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional

AV Nodal Reentrant Tachycardia Study

NCT00618683
View directory record Official record
Conditions
Tachycardia, Atrioventricular Nodal Reentry
Interventions
Cardiac Invasive Electrophysiological Study
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
16 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2021
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 25, 2026, 3:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

KCNQ1 Cascade Screening

NCT03783975
View directory record Official record
Conditions
Long QT Syndrome
Interventions
Simplified Cascade Screening
Genetic
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
Not listed
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional

Effectiveness of the Eko Digital Stethoscope in Capturing Infant ECGs

NCT06382207
View directory record Official record
Conditions
Tachyarrhythmia
Interventions
Eko Duo electronic stethoscope, CORE 500 electronic stethoscope
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 1 Year
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 25, 2026, 3:35 PM EDT
Terminated Not applicable Interventional

Unpinning Termination Therapy for VT (US)

NCT03093051
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Unpinning Termination therapy
Device
Lead sponsor
Cardialen, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
7
States / cities
Sacramento, California • Des Moines, Iowa • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics of Eleclazine in Adults With Normal and Impaired Renal Function

NCT02441829
View directory record Official record
Conditions
Long QT Syndrome
Interventions
Eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
5
States / cities
DeLand, Florida • Miami, Florida • Orlando, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional

Pharmacist Use of ECG to Inform Drug Therapy Decisions for Patients Receiving QT Prolonging Medications

NCT04000542
View directory record Official record
Conditions
Torsades de Pointe Caused by Drug (Disorder), Torsades de Pointes, Qt Interval, Variation in
Interventions
Pharmacist Intervention
Other
Lead sponsor
Northeast Iowa Medical Education Foundation
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Waterloo, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response

NCT00355797
View directory record Official record
Conditions
Bradycardia
Interventions
Closed Loop Stimulation (CLS), Standard Rate Adaptive (R) Technology, Non-rate adaptive (DDD) pacing
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
99
States / cities
Albertville, Alabama • Gadsden, Alabama • Jasper, Alabama + 82 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 25, 2026, 3:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry

NCT06455488
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug, EKG, Cardioversion, Echocardiogram
Procedure · Device · Drug + 1 more
Lead sponsor
CorVita Science Foundation
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 25, 2026, 3:35 PM EDT
Completed Not applicable Interventional

BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP S

NCT06540079
View directory record Official record
Conditions
Sinus Node Dysfunction, Bradycardia, Atrioventricular Block
Interventions
Solia CSP S lead
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
10
States / cities
Phoenix, Arizona • Ventura, California • Sarasota, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 25, 2026, 3:35 PM EDT
Completed No phase listed Observational

Brain Perfusion and Hemodynamic Stability in Patients Undergoing Radiofrequency Ablation of Ventricular Tachycardia

NCT01695551
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Data Collection Forms
Other
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Oct 25, 2026, 3:35 PM EDT
Terminated Phase 4 Interventional Results available

Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators

NCT01557842
View directory record Official record
Conditions
Ventricular Tachycardia, Ischemic
Interventions
Drug Treatment, Catheter Ablation
Drug · Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
23
States / cities
Los Angeles, California • San Francisco, California • Aurora, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Oct 25, 2026, 3:35 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

NCT03218137
View directory record Official record
Conditions
Premature Ventricular Contraction (PVC)
Interventions
Adenosine
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 25, 2026, 3:35 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Hemodynamic Response of Neuropathic And Non-Neuropathic POTS Patients To Adrenoreceptor Agonist And Antagonist

NCT03070730
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
Interventions
Droxidopa, Atenolol, Placebos
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Oct 25, 2026, 3:35 PM EDT
Withdrawn Not applicable Interventional

Stereotactic Ablative Radiotherapy (SAbR) for Treatment of Ventricular Tachycardia (VT) Refractory Standard Invasive Ablation Techniques

NCT04334811
View directory record Official record
Conditions
Tachycardia, Ventricular
Interventions
Stereotactic ablative radiotherapy
Radiation
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2022 · Synced Oct 25, 2026, 3:35 PM EDT
Active, not recruiting Not applicable Interventional

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

NCT00962728
View directory record Official record
Conditions
Postural Tachycardia Syndrome, Postural Orthostatic Tachycardia Syndrome
Interventions
Inspiratory Threshold Device (Res-Q-Gard ITD), Sham Inspiratory Threshold Device
Device
Lead sponsor
Alfredo Gamboa
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 25, 2026, 3:35 PM EDT
Terminated No phase listed Observational Results available

Optisure Lead Post Approval Study

NCT02235545
View directory record Official record
Conditions
Heart Failure, Tachycardia, Ventricular
Interventions
St. Jude Medical Optisure Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,735 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
46
States / cities
Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 42 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 25, 2026, 3:35 PM EDT