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ClinicalTrials.gov public records Last synced Oct 9, 2026, 2:55 AM EDT

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Showing 49–68 of 68 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Coronary Artery Bypass Graft Surgery Patients Clear all
Completed Phase 3 Interventional Results available

Intensive Insulin Therapy in Patients Undergoing Coronary Artery Bypass Surgery

NCT01361594
View directory record Official record
Conditions
Diabetes
Interventions
Regular insulin (intensive treatment), Regular Insulin (conventional treatment)
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 31, 2014 · Synced Oct 9, 2026, 2:55 AM EDT
Terminated Not applicable Interventional

Brain Oxygenation Monitoring in Patients Undergoing Coronary Artery Bypass Surgery

NCT00137527
View directory record Official record
Conditions
Neurological Manifestations
Interventions
Optimizing hemodynamic and anesthetic parameters to improve cerebral perfusion
Device
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 17, 2014 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 4 Interventional

Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone

NCT05681182
View directory record Official record
Conditions
Post Operative Atrial Fibrillation
Interventions
CardiaMend with the Addition of Amiodarone
Combination Product
Lead sponsor
WakeMed Health and Hospitals
Other
Eligibility
20 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 4 Interventional Results available

Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI

NCT03810417
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Digoxin Antibodies Fab Fragments, Placebo, Baseline EO > 360 pM, EO < 360 pM
Drug · Other · Diagnostic Test
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 9, 2026, 2:55 AM EDT
Completed No phase listed Observational

Platelet Reactivity After CABG

NCT01793597
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Oct 9, 2026, 2:55 AM EDT
Terminated Phase 2 Interventional Results available

Effect of GLP - 1 (7-36 Amide) on Myocardial Function Following Coronary Artery Bypass (CABG) Surgery

NCT00966654
View directory record Official record
Conditions
CABG
Interventions
Placebo, GLP-1 (7-36) amide
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Not applicable Interventional Results available

Transitional Rehabilitation in CABG Patients

NCT03892460
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
Interventions
neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
50 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 9, 2026, 2:55 AM EDT
Terminated No phase listed Observational

The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices

NCT01481012
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
13
States / cities
Birmingham, Alabama • San Diego, California • Oak Lawn, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2011 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 4 Interventional Results available

Sugammadex and Decreased Time to Extubation

NCT03196167
View directory record Official record
Conditions
Coronary Artery Bypass Graft and/or Aortic Valve Replacement Surgery
Interventions
Sugammadex, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 9, 2026, 2:55 AM EDT
Terminated Phase 2 Interventional

Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery

NCT00628264
View directory record Official record
Conditions
Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Kidney Injury
Interventions
AP214, Placebo
Drug
Lead sponsor
Action Pharma A/S
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 1, 2009 · Synced Oct 9, 2026, 2:55 AM EDT
Recruiting Early Phase 1 Interventional

Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone

NCT06063538
View directory record Official record
Conditions
Atrial Fibrillation, Post-Op Complication
Interventions
CardiaMend in Combination with Amiodarone
Combination Product
Lead sponsor
University of Chicago
Other
Eligibility
20 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 9, 2026, 2:55 AM EDT
Not yet recruiting Phase 3 Interventional

A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.

NCT07357675
View directory record Official record
Conditions
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery(CABG)
Interventions
EA-230 90mg/kg/hour, Placebo
Drug
Lead sponsor
EBI Anti Sepsis BV
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 3 Interventional Results available

Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass

NCT02025621
View directory record Official record
Conditions
Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
Interventions
Levosimendan, Placebo
Drug
Lead sponsor
Tenax Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
882 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
49
States / cities
Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2018 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 3 Interventional

A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG

NCT00402506
View directory record Official record
Conditions
Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury
Interventions
(MC-1) Pyridoxal 5'-phosphate
Drug
Lead sponsor
Medicure
Industry
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2007 · Synced Oct 9, 2026, 2:55 AM EDT
Recruiting No phase listed Observational

SSVC-CI During CABG

NCT06645327
View directory record Official record
Conditions
Coronary Artery Bypass Grafting Surgery (CABG)
Interventions
a change in operating room table position, which will mimic an IV fluid bolus
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Phase 4 Interventional Results available

Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery

NCT03939923
View directory record Official record
Conditions
Surgery, Coronary Artery Disease
Interventions
Rocuronium, Neostigmine, Glycopyrrolate, Sugammadex
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Oct 9, 2026, 2:55 AM EDT
Terminated No phase listed Observational

LifeVest Post-CABG Registry

NCT01448005
View directory record Official record
Conditions
Sudden Cardiac Death, Ventricular Fibrillation, Ventricular Tachycardia, Ventricular Dysfunction, Myocardial Ischemia
Interventions
wearable defibrillator (LifeVest)
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
Sacramento, California • Atlanta, Georgia • Takoma Park, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 9, 2026, 2:55 AM EDT
Not yet recruiting Phase 2 Interventional

Epicardial Delivery of XC001 Gene Therapy to Promote Angiogenesis in CAD Patients Undergoing Treatment With CABG

NCT07118449
View directory record Official record
Conditions
Coronary Artery Disease (CAD)
Interventions
XC001, A195/placebo
Drug
Lead sponsor
XyloCor Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 9, 2026, 2:55 AM EDT
Completed Not applicable Interventional Results available

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

NCT02100722
View directory record Official record
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 9, 2026, 2:55 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Assessment of Platelet Function in Patients Undergoing Open Heart Surgery

NCT05441358
View directory record Official record
Conditions
Coronary Artery Bypass Grafting, Open Heart Surgery, Aortic Surgery or Redo Surgery, On-pump Double or Triple Valve Procedures
Interventions
Open Heart Surgery
Procedure
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 9, 2026, 2:55 AM EDT