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ClinicalTrials.gov public records Last synced Nov 6, 2026, 6:50 PM EST

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Showing 1–24 of 117 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Critical Limb Ischemia Clear all

Conditions: Critical Limb Ischemia
Interventions: Not listed
Lead sponsor: HyperMed; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Critical Limb Ischemia
Interventions: care as usual; Other
Lead sponsor: Saint Luke's Health System; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: New Haven, Connecticut • Cleveland, Ohio

Conditions: Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Interventions: Actionable remotely generated health data, Non-Actionable remotely generated health data; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 60 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Peripheral Arterial Disease, Claudication, Critical Limb Ischemia
Interventions: Atherectomy; Device
Lead sponsor: Volcano Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 5
States / cities: Tucson, Arizona • Detroit, Michigan • Saginaw, Michigan + 2 more

Conditions: Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia, Graft Occlusion, Vascular, Hyperplasia
Interventions: CGT003 (E2F Duplex Decoy); Drug
Lead sponsor: Anesiva, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 116
States / cities: Birmingham, Alabama • Mobile, Alabama • Tucson, Arizona + 61 more

Conditions: Peripheral Artery Disease, Diabetes Mellitus, Chronic Limb-Threatening Ischemia
Interventions: SPECT/CT perfusion imaging, PET/CT perfusion imaging; Diagnostic Test
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Peripheral Arterial Disease
Interventions: Tack Endovascular System; Device
Lead sponsor: Philips Clinical & Medical Affairs Global; Industry
Eligibility: 18 Years and older
Enrollment: 233 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 37
States / cities: Yuma, Arizona • Fremont, California • Denver, Colorado + 33 more

Conditions: Critical Limb Ischemia
Interventions: Cord blood stem cell injection; Biological
Lead sponsor: Richard Burt, MD; Other
Eligibility: 18 Years to 72 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Limb Threatening Ischemia
Interventions: Transverse Tibial Bone Transport, TrueLok Elevate; Procedure · Device
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 95 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Critical Limb Ischemia, Peripheral Arterial Disease
Interventions: Not listed
Lead sponsor: CryoLife, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 7
States / cities: Phoenix, Arizona • Palo Alto, California • San Francisco, California + 4 more

Conditions: Critical Limb Ischemia, Malnutrition, Nutritional Supplements
Interventions: Ensure Surgery Immunonutrition Shake, Ensure Enlive Advanced Nutrition Shake; Drug
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 99 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication, Limb Ischemia, Limb Ischemia, Critical
Interventions: MY01 + Standard of Care, 14-Gauge Slit Catheter + Standard of Care, Standard of Care; Device · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Mechanical Ventilation Complication, Arterial Thrombosis, Limb Ischemia, Shock, Hypotension, Bloodstream Infection, Vasopressor Adverse Reaction, Renal Failure
Interventions: Restricted-use of arterial catheter, Standard-use of arterial catheter; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Critical Limb Ischemia
Interventions: ASCT01 (Autologous Stem Cell Transplantation); Biological
Lead sponsor: Lifecells, LLC.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: North Kansas City, Missouri

Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
Interventions: Serranator, POBA; Device
Lead sponsor: Cagent Vascular LLC; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Critical Limb Ischemia
Interventions: Liposuction, Stem Cell Injection; Procedure · Other
Lead sponsor: Ageless Regenerative Institute; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Peripheral Vascular Disease
Interventions: Remodulin (treprostinil sodium) Injection; Drug
Lead sponsor: United Therapeutics; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003
U.S. locations: 4
States / cities: Springfield, Illinois • Worcester, Massachusetts • Albany, New York + 1 more

Conditions: Chronic Limb-Threatening Ischemia
Interventions: MiraQ with Transit-Time Flow Measurement (TTFM) and L15 High Frequency Ultrasound (HFUS) probes; Device
Lead sponsor: Medistim ASA; Industry
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Critical Limb Ischemia
Interventions: HGF Plasmid (AMG0001), Matching Placebo; Biological
Lead sponsor: AnGes USA, Inc.; Industry
Eligibility: 40 Years to 90 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 28
States / cities: Tucson, Arizona • Little Rock, Arkansas • La Jolla, California + 23 more

Conditions: Critical Limb Ischemia
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 1,009 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Peripheral Artery Disease
Interventions: FlowMet-R, ABI, TBI; Diagnostic Test
Lead sponsor: Medtronic Endovascular; Industry
Eligibility: 40 Years and older
Enrollment: 195 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 5
States / cities: Des Moines, Iowa • Chesterfield, Missouri • New York, New York + 2 more

Conditions: Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions: BGC101 (autologous EnEPC preparation), Control medium; Biological
Lead sponsor: BioGenCell Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 3
States / cities: San Francisco, California • New Haven, Connecticut • Baltimore, Maryland

Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
Interventions: BOLD-MRI; Other
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 19 Years to 89 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Peripheral Vascular Disease
Interventions: Ecraprost in lipid emulsion; Drug
Lead sponsor: Tanabe Pharma Corporation; Industry
Eligibility: 40 Years and older
Enrollment: 560 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 20
States / cities: Phoenix, Arizona • Tucson, Arizona • Glendale, California + 17 more

Search by objective public record fields.

Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities

SCOPE CLI (Shifting Care and Outcomes for Patients With Endangered Limbs - Critical Limb Ischemia)

The ROAMM-EHR Study

Phoenix Post-Approval Registry - Using the Phoenix Atherectomy Systems

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System® in Below the Knee Arteries

Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia

Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)

Cryopreserved Saphenous Vein Allograft in Patients With Critical Limb Ischemia for Peripheral Revascularization

Nutrition in Patient With Critical Limb Ischemia

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients

Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment

Study to Assess Efficacy and Safety of Bone Marrow Derived Stem Cells in Patients With Critical Limb Ischemia

Serranator Recoil Study

Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia

Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft

Peripheral Bypass Trial for Completion Control

Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia

BEST vCLI Registry

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)

BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease