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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:51 AM EDT

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Showing 193–216 of 241 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Decay Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training

NCT05302791
View directory record Official record
Conditions
Exercise Training
Interventions
Muscle Cooling, Resistance Exercise
Device · Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 1 Interventional

A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer

NCT00001683
View directory record Official record
Conditions
Lymphoma, Melanoma, Neoplasm Metastasis, Renal Cell Carcinoma
Interventions
COL-3
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Study to Evaluate the Safety and Microbiology of C16G2 in Adolescent and Adult Dental Subjects

NCT02509845
View directory record Official record
Conditions
Dental Caries
Interventions
C16G2, Placebo
Drug · Other
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
12 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
5
States / cities
Indianapolis, Indiana • Kalispell, Montana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant

NCT03306433
View directory record Official record
Conditions
Dental Caries
Interventions
UDMA-K18 smooth surface sealant
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 89 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 21, 2026, 6:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances

NCT04186065
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Hiroko Nagaoka
Other
Eligibility
10 Years to 70 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite

NCT04059250
View directory record Official record
Conditions
Dental Caries, Denture, Partial, Removable
Interventions
Nobio composite, traditional composite
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2021 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Study of How Insulin Peglispro (LY2605541) and Insulin Glargine Affect the Breakdown of Fat and Sugar in Type 1 Diabetics

NCT01925989
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
LY2605541, Insulin Glargine
Biological
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 1, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children

NCT04368533
View directory record Official record
Conditions
Plaque, Dental, Caries, Dental, Oral Hygiene
Interventions
Livionex Dental Gel, A standard children's toothpaste containing 1500 ppm fluoride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Months to 12 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 3 Interventional Results available

TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine

NCT00385008
View directory record Official record
Conditions
Migraine Disorders
Interventions
Combination Product (sumatriptan succinate / naproxen sodium), RELPAX(eletriptan) 40mg Tablet
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Early Phase 1 Interventional

Intensive Preventative Dental Program Pilot Study

NCT07218068
View directory record Official record
Conditions
Dental Diseases
Interventions
Fluoride varnish, Regular Care, Medical Oncology Care Team
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BEhavioral EConomics for Oral Health iNnovation Pilot Trial

NCT03862443
View directory record Official record
Conditions
Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene, Dental Caries
Interventions
Fixed Incentive, Drawing Incentive
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Months to 42 Months
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Pressure in the Flank Position

NCT00395980
View directory record Official record
Conditions
Tissue Breakdown
Interventions
surgical table pressure mat
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2008 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Results available

High-strength Glass-ionomer Dental Restorations

NCT01523613
View directory record Official record
Conditions
Dental Caries
Interventions
Chemfil ROCK Glassionomer restoration, Fuji IX GP Extra Glassionomer restoration
Device
Lead sponsor
Mathilde Peters, DMD, PhD
Other
Eligibility
7 Years to 16 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 3, 2017 · Synced Oct 21, 2026, 6:51 AM EDT
Active, not recruiting Not applicable Interventional

Celtra Quatro Crown Study

NCT04604301
View directory record Official record
Conditions
Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
Interventions
Celtra Quatro
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 110 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Not listed Phase 2 Interventional

Exercise For Sub-acute Stroke Patients in Jamaica

NCT01392391
View directory record Official record
Conditions
Stroke
Interventions
Task Oriented Exercise Training, Stroke Care "Get with the Guidelines"
Procedure
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Oct 21, 2026, 6:51 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers

NCT01147835
View directory record Official record
Conditions
Asthma, Dental Caries
Interventions
Chinese Licorice Root
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
4 Years to 16 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective Comparison of Indirect Pulp Therapy and Mineral Trioxide Aggregate Pulpotomy in Decayed Primary Molars

NCT02620826
View directory record Official record
Conditions
Dental Pulp Capping
Interventions
Indirect pulp therapy, Pulpotomy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 12 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intraoral Imaging at Clinical Crown Lengthening

NCT03064217
View directory record Official record
Conditions
Dental Caries of Root Surface, Surgery
Interventions
Making impression at surgery
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Disintegration, Safety, and Acceptability of Placebo Vaginal Inserts for the Delivery of Vaginal Products

NCT02534779
View directory record Official record
Conditions
Vaginal Diseases
Interventions
Placebo Vaginal Insert
Other
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 2, 2016 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Casein Protein and Leucine Supplementation in Chronic Obstructive Pulmonary Disease (COPD)

NCT01734473
View directory record Official record
Conditions
COPD
Interventions
Hydrolyzed casein protein, Hydrolyzed casein protein + carbohydrates, Hydrolyzed casein protein + leucine, Hydrolyzed casein protein + carbohydrates + leucine, 4 levels of hydrolyzed casein protein + carbohydrates
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 1 Interventional

Chlorhexidine Gel Therapy for Cariogenic Oral Microflora

NCT01036412
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
1% Chlorhexidine Gluconate Gel, Surveys
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride

NCT01563172
View directory record Official record
Conditions
Dental Caries
Interventions
Sodium fluoride / silica and carbopol, 0.5g, Sodium fluoride / silica and carbopol, 1.5g, Fluoride free dentifrice
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses

NCT05601154
View directory record Official record
Conditions
Dental Caries
Interventions
Crest Cavity Protection toothpaste, Crest Cavity Protection toothpaste followed by Act Mint Fluoride Rinse, Colgate PreviDent 5000+ toothpaste, Colgate PreviDent 5000+ toothpaste followed by Act Mint Fluoride Rinse
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional

Clinical Performance of Posterior Composite Tooth Fillings in Adults

NCT03175627
View directory record Official record
Conditions
Dental Caries, Dental Restoration Failure
Interventions
Filtek One, Filtek Z250
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 21, 2026, 6:51 AM EDT