- Conditions
- Intervertebral Disc Disease, Intervertebral Disc Degeneration, Spondylosis, Spondylolisthesis, Spinal Stenosis
- Interventions
- NuCel with Autograft
- Other
- Lead sponsor
- NuTech Medical, Inc
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2019
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
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Showing 1–24
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- Conditions
- Degenerative Disc Disease
- Interventions
- ILIF
- Procedure
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Santa Monica, California • Gainesville, Florida + 5 more
- Conditions
- Spinal Disease, Degenerative Disc Disease
- Interventions
- OssiMend™ Bioactive Moldable
- Device
- Lead sponsor
- Collagen Matrix
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 4
- States / cities
- Encinitas, California • Hartford, Connecticut • Somerset, New Jersey + 1 more
- Conditions
- Radiculopathy, Herniated Disc, Disc Degeneration
- Interventions
- Regenexx PL-Disc, Steroid Epidural
- Procedure
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- Degenerative Disc Disease(DDD)
- Interventions
- Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
- Device · Procedure
- Lead sponsor
- Providence Medical Technology, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Paducah, Kentucky
- Conditions
- Degenerative Disc Disease
- Interventions
- XL TDR, Lumbar fusion surgery
- Device · Other
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 246 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 17
- States / cities
- Campbell, California • Thousand Oaks, California • Durango, Colorado + 14 more
- Conditions
- Degenerative Lumbar Spondylolisthesis
- Interventions
- Use of OP-1 Putty in Uninstrumented posterolateral fusion
- Device
- Lead sponsor
- Olympus Biotech Corporation
- Industry
- Eligibility
- 18 Years to 81 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2005
- U.S. locations
- 5
- States / cities
- New Haven, Connecticut • Chicago, Illinois • Royal Oak, Michigan + 2 more
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Interventions
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Device
- Lead sponsor
- Nitin Agarwal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Subjects Treated With NMP as Part of Their Spine Surgery, Degenerative Disc Disease (DDD)
- Interventions
- NMP
- Device
- Lead sponsor
- Red Rock Regeneration Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Baton Rouge, Louisiana • Shreveport, Louisiana
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Interventions
- General anesthetic, SA + ESP
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Degenerative Disc Disease
- Interventions
- One level Mobi-C and one level fusion
- Device
- Lead sponsor
- Highridge Medical
- Industry
- Eligibility
- 22 Years to 69 Years
- Enrollment
- 97 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 2
- States / cities
- Sacramento, California • Southfield, Michigan
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
- Interventions
- Surgery with the Keos Lumbar Interbody Fusion Device
- Device
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Lancaster, Pennsylvania
- Conditions
- Degenerative Disc Disease
- Interventions
- One-level or two-level anterior lumbar interbody fusion, InQu Bone Graft Extender and Substitute mixed with BMAC, Synthes Spinal Instrumentation
- Procedure · Biological · Device
- Lead sponsor
- Kansas Joint and Spine Institute
- Network
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- Wichita, Kansas
- Conditions
- Degenerative Disc Disease
- Interventions
- Natural Matrix Protein (NMP)
- Biological
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Shreveport, Louisiana
- Conditions
- Spinal Fusion
- Interventions
- NanoBone Bone Graft Substitute
- Other
- Lead sponsor
- Artoss Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 330 participants
- Timeline
- 2020 – 2025
- U.S. locations
- 6
- States / cities
- Chandler, Arizona • Tempe, Arizona • San Diego, California + 3 more
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis, Lumbar Radiculopathy, Lumbar Spine Instability, Synovial Cyst, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Interventions
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Drug
- Lead sponsor
- John O'Toole
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease, Disc Herniation
- Interventions
- SeaSpine Shoreline
- Device
- Lead sponsor
- Research Source
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Southfield, Michigan
- Conditions
- Cervical Spondylosis With Myelopathy, Cervical Radiculopathy, Cervical Disc Herniation, Degenerative Disc Disease
- Interventions
- Cervical arthroplasty, Semi-Constrained Nuvasive Simplify, Unconstrained Biomet Zimmer Mobi-C
- Procedure · Device
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Degenerative Disc Disease
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Prolapsed Lumbar Disc, Prolapsed Cervical Disc, Intervertebral Disc Degeneration, Spondylolisthesis, Grade 1, Intervertebral Disc Displacement
- Interventions
- Not listed
- Lead sponsor
- Wenzel Spine
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • San Antonio, Texas
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- AlterG
- Other
- Lead sponsor
- Justin Parker Neurological Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Degenerative Disc Disease
- Interventions
- Spinal fusion
- Procedure
- Lead sponsor
- Flexuspine, Inc.
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2008
- U.S. locations
- 6
- States / cities
- Clearwater, Florida • Temple Terrace, Florida • Baltimore, Maryland + 3 more
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Interventions
- Not listed
- Lead sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Odessa, Florida
- Conditions
- Chronic Low Back Pain, Degenerative Disc Disease
- Interventions
- Autologous stem cells, Corticosteroid, Local anesthetic
- Other · Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland