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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:23 PM EDT

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Showing 1–24 of 1,794 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Degenerative Arthritis Clear all
Not listed Not applicable Interventional

Impact of Sensor Technology in Knee OA

NCT05222503
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Knee Brace + OPUM Digital Knee, Knee Brace
Device
Lead sponsor
OPUM Technologies US LTD
Other
Eligibility
40 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Oct 22, 2026, 7:23 PM EDT
Completed No phase listed Observational

Post-PMA Approval Study: 10 Year Follow-Up IDE Subjects

NCT00721994
View directory record Official record
Conditions
Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
Interventions
Cormet Hip Resurfacing System
Device
Lead sponsor
Corin
Industry
Eligibility
Not listed
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
5
States / cities
Merritt Island, Florida • Sarasota, Florida • Springfield, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2018 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

NCT01280903
View directory record Official record
Conditions
Osteoarthritis, Knee, Hypertension
Interventions
STAR Intervention, Attention-Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 7:23 PM EDT
Withdrawn Phase 2 Interventional

A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKA

NCT04493229
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Not applicable Interventional Results available

The Viability of Short Stems in Total Hip Arthroplasty

NCT02577822
View directory record Official record
Conditions
Osteoarthritis of Hip
Interventions
Taperloc standard length stem, Taperloc short length stem
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Clinical Trial Examining the Effects on Osteoarthritic Knee Pain of CGS-200-1, CGS-200-5 and Vehicle Control

NCT03528369
View directory record Official record
Conditions
Osteoarthritis, Knee, Pain
Interventions
CGS-200-1, CGS-200-5, CGS-200 Vehicle
Drug
Lead sponsor
Propella Therapeutics
Industry
Eligibility
35 Years to 75 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
6
States / cities
Clearwater, Florida • Tampa, Florida • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Not applicable Interventional

Yoga for Rheumatoid Arthritis

NCT00349869
View directory record Official record
Conditions
Rheumatoid Arthritis, Osteoarthritis
Interventions
yoga
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated Phase 3 Interventional Results available

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

NCT00809354
View directory record Official record
Conditions
Osteoarthritis, Arthritis
Interventions
NSAID, tanezumab
Drug · Biological
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 99 Years
Enrollment
2,720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
250
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 161 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 22, 2026, 7:23 PM EDT
Enrolling by invitation No phase listed Observational

Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert

NCT04816773
View directory record Official record
Conditions
Joint Diseases, Osteoarthritis, Arthritis Knee, Avascular Necrosis
Interventions
EVOLUTION® NitrX™
Device
Lead sponsor
MicroPort Orthopedics Inc.
Industry
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2035
U.S. locations
1
States / cities
Fremont, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated Not applicable Interventional

Ascension® Humeral Resurfacing Arthroplasty Follow-Up Study

NCT02029469
View directory record Official record
Conditions
Shoulder Arthritis Osteoarthritis, Rheumatoid Arthritis Shoulder, Acquired Deformity of Head, Post-traumatic Arthrosis of Other Joints, Shoulder Region
Interventions
Ascension HRA device
Device
Lead sponsor
Ascension Orthopedics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Bay Pines, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2014 · Synced Oct 22, 2026, 7:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

R3® Acetabular System in Patients With Degenerative Hip Disease

NCT01407029
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2017
U.S. locations
5
States / cities
Vero Beach, Florida • Chicago, Illinois • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated No phase listed Observational

Journey II BCS CMS Total Knee System Compared to Other PS Total Knee Systems in PT Setting

NCT02820766
View directory record Official record
Conditions
Osteoarthritis, Degenerative Arthritis, Traumatic Arthritis
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Annapolis, Maryland • Eugene, Oregon • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated Phase 2 Interventional

A 52-Week Study to Assess the Effects of MK0822 on Knee Osteoarthritis (MK-0822-011)

NCT00397683
View directory record Official record
Conditions
Osteoarthritis
Interventions
MK0822
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
40 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
12
States / cities
Palm Desert, California • Pomona, California • Torrance, California + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Phase 2 Interventional Results available

A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale

NCT03570554
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Naproxen Sodium (Aleve, BAY117031), Acetaminophen ER, Celecoxib, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
40 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Chandler, Arizona • Pinellas Park, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2020 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Phase 4 Interventional Results available

Hormone Function in Men Treated for Pain With Opioids or Placebo

NCT00737737
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
MS Contin, Placebo
Drug
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
30 Years to 65 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Oct 22, 2026, 7:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Subgroups of Older Adults With Back Pain and Multiple Chronic Conditions

NCT03632122
View directory record Official record
Conditions
Low Back Pain, Depression, Anxiety, Osteoarthritis
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
8,344 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated No phase listed Observational

Total Knee Replacement With Duracon® and Vanguard™ Prostheses

NCT00588887
View directory record Official record
Conditions
Degenerative Arthritis, Osteoarthritis, Rheumatoid Arthritis, Knee Arthritis
Interventions
Duracon®, Vanguard™
Device
Lead sponsor
Biomet Orthopedics, LLC
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Warsaw, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated Phase 1 Interventional

CAM Procedure With BMAC for Shoulder OA

NCT04826224
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Concentrated bone marrow aspirate administration after Comprehensive Arthroscopic Management (CAM) surgical procedure.
Biological
Lead sponsor
Shane A. Shapiro
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis

NCT06229691
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
30 minute treadmill walk
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
55 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Functional Brain Imaging - Acupuncture and Osteoarthritis

NCT00070824
View directory record Official record
Conditions
Osteoarthritis
Interventions
acupuncture
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2007 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated No phase listed Observational

A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells

NCT04405297
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis, Ankle Osteoarthritis, Shoulder Osteoarthritis, Wrist Osteoarthritis
Interventions
Adipose-derived regenerative cells
Device
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 22, 2026, 7:23 PM EDT
Completed Not applicable Interventional

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

NCT03719417
View directory record Official record
Conditions
Knee Osteoarthritis, Post-traumatic Osteoarthritis
Interventions
Unicompartmental Biologic Arthroplasty, Extensive Biologic Arthroplasty
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Oct 22, 2026, 7:23 PM EDT
Recruiting No phase listed Observational

Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis

NCT06781463
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
Interventions
Registry (N/A)
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 22, 2026, 7:23 PM EDT
Terminated No phase listed Observational

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

NCT04349956
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
UBX0101 or placebo
Drug
Lead sponsor
Unity Biotechnology, Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
17
States / cities
Mobile, Alabama • Tempe, Arizona • Tucson, Arizona + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 22, 2026, 7:23 PM EDT