- Conditions
- Degeneration of Lumbar Intervertebral Disc
- Interventions
- Structural Allograft Spacer, OptiMesh 1500S
- Device
- Lead sponsor
- Spineology, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2013
- U.S. locations
- 11
- States / cities
- Los Angeles, California • Coeur d'Alene, Idaho • Aurora, Illinois + 8 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 262
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Degenerative Disc Disease (DDD)
- Interventions
- Lumbar Interbody Fusion Devices
- Device
- Lead sponsor
- Spine and Scoliosis Research Associates
- Other
- Eligibility
- 18 Years to 110 Years
- Enrollment
- 465 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- San Francisco, California • New York, New York • Charlotte, North Carolina + 1 more
- Conditions
- Cervical Radiculopathy
- Interventions
- CONDUIT Interbody Cervical System with DePuy Synthes Cervical Plating System
- Device
- Lead sponsor
- Research Source
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Intradiscal rhGDF-5, Water for injection
- Drug · Other
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 10
- States / cities
- Phoenix, Arizona • Santa Monica, California • Durango, Colorado + 7 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Avenue® L Interbody Fusion System (LDR Spine)
- Device
- Lead sponsor
- LDR Spine USA
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 4
- States / cities
- Thornton, Colorado • Atlanta, Georgia • Neptune City, New Jersey + 1 more
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Grade 1, Retrolisthesis
- Interventions
- AccuLIF expandable TLIF cage
- Device
- Lead sponsor
- Stryker Spine
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Interventions
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Device
- Lead sponsor
- Nitin Agarwal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Interventions
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
- Drug · Other
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years to 88 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Degenerative Disc Disease
- Interventions
- Virtuos
- Device
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 3
- States / cities
- New Britain, Connecticut • Royal Oak, Michigan • Dallas, Texas
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Stenosis
- Interventions
- Modulus ALIF System
- Device
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 123 participants
- Timeline
- 2022 – 2024
- U.S. locations
- 5
- States / cities
- Orange, California • San Diego, California • Atlanta, Georgia + 2 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- SB-01 For Injection, Sham Needle
- Drug
- Lead sponsor
- Spine BioPharma, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 417 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 30
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Napa, California + 24 more
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- PLF with autograft, PLF with NeoFuse
- Procedure · Biological
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Degenerative Lumbar Disc Disease
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 2
- States / cities
- Durango, Colorado • Marrietta, Georgia
- Conditions
- Stenosis, Herniated Nucleus Pulposus, Degenerative Disc Disease, Spondylosis, Myelopathy, Radiculopathy, Myeloradiculopathy
- Interventions
- Methylprednisolone, Saline
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- Not listed
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 4
- States / cities
- Orange, California • Jacksonville, Florida • Charlotte, North Carolina
- Conditions
- Degenerative Lumbar Disc Disease
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 324 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 12
- States / cities
- La Jolla, California • Tampa, Florida • Atlanta, Georgia + 8 more
- Conditions
- Degenerative Disc Disease
- Interventions
- FlareHawk Interbody Fusion System
- Device
- Lead sponsor
- Integrity Implants Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 129 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 3
- States / cities
- Savannah, Georgia • Charlotte, North Carolina • Akron, Ohio
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 2
- States / cities
- Thousand Oaks, California • Atlanta, Georgia
- Conditions
- Degenerative Disc Disease
- Interventions
- Placebo, AMG0103
- Drug
- Lead sponsor
- AnGes, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 6
- States / cities
- Los Angeles, California • San Diego, California • St. Petersburg, Florida + 2 more
- Conditions
- Spondylolisthesis, Stenosis
- Interventions
- Copios
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 6
- States / cities
- Orlando, Florida • Belleville, Illinois • Indianapolis, Indiana + 3 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Not listed
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 9
- States / cities
- South Bend, Indiana • Southfield, Michigan • Missoula, Montana + 5 more
- Conditions
- Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
- Interventions
- MagnetOs Flex Matrix, Trinity Elite
- Device
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 7
- States / cities
- Hartford, Connecticut • Columbia, Maryland • Bloomfield Hills, Michigan + 4 more
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Stenosis, Spondylitis, Spondylosis
- Interventions
- Not listed
- Lead sponsor
- Allina Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Lumbar Disc Disease
- Interventions
- Autologous bone marrow aspirate injected intradiscal after microdiscectomy, Discectomy only
- Procedure
- Lead sponsor
- New York Presbyterian Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York