- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spondylosis
- Interventions
- One or two level lumbar interbody fusion surgery, Nucel
- Procedure · Other
- Lead sponsor
- Organogenesis
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Shreveport, Louisiana • Charlotte, North Carolina
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
- Interventions
- Propranolol Hcl 40mg Tab, Placebo oral tablet
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Lumbar Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Spondylosis, Intervertebral Disk Displacement, Intervertebral Disk Degeneration, Spinal Diseases, Bone Diseases, Musculoskeletal Diseases, Spondylolysis
- Interventions
- NuCel, Demineralized Bone Matrix
- Biological
- Lead sponsor
- OhioHealth
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 2
- States / cities
- Columbus, Ohio
- Conditions
- Spondylolisthesis, Scoliosis, Intervertebral Disc Disease
- Interventions
- OsteoAMP
- Other
- Lead sponsor
- Bioventus LLC
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 9
- States / cities
- New Haven, Connecticut • Chicago, Illinois • Kansas City, Kansas + 6 more
- Conditions
- Degenerative Disc Disease
- Interventions
- NuQu, Placebo
- Biological · Other
- Lead sponsor
- ISTO Technologies, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2020
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- In this evaluation, no interventions are performed. It is a data collection effort only. The "procedure" for this study is the data collection effort.
- Other
- Lead sponsor
- Spineology, Inc
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 197 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 10
- States / cities
- Fremont, California • Loma Linda, California • Napa, California + 7 more
- Conditions
- Low Back Pain
- Interventions
- Interspinous process and dynamic stabilization, Conservative Care
- Device
- Lead sponsor
- Zimmer Spine
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2012
- U.S. locations
- 17
- States / cities
- Phoenix, Arizona • Beverly Hills, California • Santa Monica, California + 13 more
- Conditions
- Degenerative Disc Disease
- Interventions
- TIDAL Cervical Interbody Fusion implant
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 73 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Paducah, Kentucky
- Conditions
- Degenerative Disc Disease
- Interventions
- Cervical or Lumbar Spinal fusion
- Device
- Lead sponsor
- K2M, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 4
- States / cities
- Shreveport, Louisiana • Cleveland, Ohio • Oklahoma City, Oklahoma + 1 more
- Conditions
- Degenerative Disc Disease
- Interventions
- ALTERA
- Device
- Lead sponsor
- Globus Medical Inc
- Industry
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease
- Interventions
- Lumbar I/F with cage and pedicle screws
- Device
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2006
- U.S. locations
- 2
- States / cities
- Dothan, Alabama • Fort Wayne, Indiana
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PureGen Osteoprogenitor Cell Allograft, Autograft bone
- Biological · Procedure
- Lead sponsor
- Alphatec Spine, Inc.
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Beverly Hills, California
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Interventions
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic, Muscle relaxant during maintenance anesthesia, Pain control with fentanyl, Bispectral Index (BIS) monitoring for depth of anesthesia, Spinal Anesthesia, Midazolam administered during spinal anesthesia, Cerebrospinal fluid collection, Administration of intrathecal morphine
- Procedure
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 218 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Stenosis
- Interventions
- Modulus ALIF System
- Device
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 123 participants
- Timeline
- 2022 – 2024
- U.S. locations
- 5
- States / cities
- Orange, California • San Diego, California • Atlanta, Georgia + 2 more
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- nanOss Bioactive - posterolateral gutter
- Device
- Lead sponsor
- Pioneer Surgical Technology, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 3
- States / cities
- La Jolla, California • San Francisco, California • Columbia, Missouri
- Conditions
- Cervical Disc Disease
- Interventions
- Zero-P
- Device
- Lead sponsor
- Synthes USA HQ, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 14
- States / cities
- Dothan, Alabama • Phoenix, Arizona • Newport Beach, California + 10 more
- Conditions
- Degenerative Disc Disease, Degenerative Scoliosis
- Interventions
- Spinal Fusion, Spinal Deformities Correction
- Device
- Lead sponsor
- VB Spine, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 5,222 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2032
- U.S. locations
- 7
- States / cities
- Jacksonville, Florida • Scarborough, Maine • Southfield, Michigan + 4 more
- Conditions
- Spondylosis, Cervical Spondylosis, Spondylolisthesis, Herniated Nucleus Pulposus, Degenerative Disc Disease
- Interventions
- ViBone
- Other
- Lead sponsor
- Elutia Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 4
- States / cities
- San Diego, California • Danbury, Connecticut • Annapolis, Maryland + 1 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years · Female only
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Prolapsed Lumbar Disc, Prolapsed Cervical Disc, Intervertebral Disc Degeneration, Spondylolisthesis, Grade 1, Intervertebral Disc Displacement
- Interventions
- Not listed
- Lead sponsor
- Wenzel Spine
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • San Antonio, Texas
- Conditions
- Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
- Interventions
- VERTICALE® Cervical System
- Device
- Lead sponsor
- Silony Medical GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease
- Interventions
- ILIF
- Procedure
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Santa Monica, California • Gainesville, Florida + 5 more
- Conditions
- Discogenic Pain
- Interventions
- Bone Marrow Concentrate, Placebo
- Other
- Lead sponsor
- APM Spine and Sports Physicians
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Virginia Beach, Virginia
- Conditions
- Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
- Interventions
- Morphine, Epinephrine, naropin
- Drug
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota