- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- Open PLIF (posterior lumbar interbody fusion), MAS PLIF
- Procedure
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 4
- States / cities
- Greensboro, North Carolina • York, Pennsylvania • Temple, Texas
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Showing 25–48
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- Conditions
- Degenerative Disc Disease
- Interventions
- ALTERA
- Device
- Lead sponsor
- Globus Medical Inc
- Industry
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal, Intervertebral Disc Injury
- Interventions
- NSSD, Sham NSSD
- Device
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Stanford, California • Tampa, Florida
- Conditions
- Degenerative Disc Disease
- Interventions
- Avenue® L Interbody Fusion System (LDR Spine)
- Device
- Lead sponsor
- LDR Spine USA
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 4
- States / cities
- Thornton, Colorado • Atlanta, Georgia • Neptune City, New Jersey + 1 more
- Conditions
- Degenerative Disc Disease, Adjacent Level Disease
- Interventions
- Annex™ Adjacent Level System
- Device
- Lead sponsor
- Spine Wave
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Interventions
- Posterior Lateral Fusion (PLF), Anterior Lumbar Interbody Fusion (ALIF), Transforaminal lumbar interbody fusion (TLIF), Posterior lumbar interbody fusion (PLIF), Extreme lateral interbody fusion (XLIF)
- Procedure
- Lead sponsor
- Exactech
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2011
- U.S. locations
- 6
- States / cities
- Long Beach, California • San Diego, California • New Hartford, New York + 3 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Lumbar Artificial Disc, Charite Artificial Disc
- Device
- Lead sponsor
- SpinalMotion
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 514 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2013
- U.S. locations
- 21
- States / cities
- Beverly Hills, California • Encinitas, California • Oakland, California + 18 more
- Conditions
- Degeneration Disc Intervertebral
- Interventions
- Abaloparatide, Placebo
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PDS System, Fusion
- Device
- Lead sponsor
- Interventional Spine, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio • Willow Grove, Pennsylvania
- Conditions
- Degenerative Disc Disease Lumbar, Spondylolisthesis, Grade 1
- Interventions
- Device: EVOS Lumbar Interbody System (EVOS-HA)
- Device
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Philadelphia, Pennsylvania
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- Trinica Anterior Lumbar Plate System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 3
- States / cities
- Daphne, Alabama • Mobile, Alabama • San Bernardino, California
- Conditions
- Degenerative Disc Disease
- Interventions
- ProDisc™-L Total Disc Replacement (TDR)
- Device
- Lead sponsor
- Synthes USA HQ, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease, Chronic Low-back Pain (cLBP), Chronic Low Back and Leg Pain, Back Pain
- Interventions
- Active Cannabis, Placebo Cannabis
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Degenerative Disc Disease
- Interventions
- Not listed
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 207 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 15
- States / cities
- Boulder, Colorado • Canton, Connecticut • Middletown, Connecticut + 11 more
- Conditions
- Low Back Pain
- Interventions
- functional anesthetic discography, provocative discography
- Procedure
- Lead sponsor
- Medtronic Spine LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 10
- States / cities
- Huntsville, Alabama • Beverly Hills, California • Escondido, California + 7 more
- Conditions
- Intervertebral Disc Degeneration
- Interventions
- Not listed
- Lead sponsor
- ISTO Technologies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2019
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Royal Oak, Michigan
- Conditions
- Cervical Degenerative Disc Disease
- Interventions
- Anterior Cervical Discectomy & Fusion
- Device
- Lead sponsor
- Synergy Spine Solutions
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 20
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Beverly Hills, California + 15 more
- Conditions
- Degenerative Disc Disease, Spine Fusion
- Interventions
- MagnetOs Putty
- Device
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Paducah, Kentucky
- Conditions
- Spinal Stenosis, Low Back Pain
- Interventions
- Decompressive laminectomy, Non-surgical treatments
- Procedure · Other
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 289 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2015
- U.S. locations
- 13
- States / cities
- Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Rexlemestrocel-L + HA mixture, Saline
- Drug
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 40
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Chula Vista, California + 37 more
- Conditions
- Low Back Pain
- Interventions
- InterFuse T, Standard of Care TLIF (Stryker AVS Unilif)
- Device
- Lead sponsor
- Vertebral Technologies, Inc.
- Industry
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Cervical Degenerative Disc Disease
- Interventions
- Cervical TDR, ACDF with plate
- Device
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2016
- U.S. locations
- 30
- States / cities
- Beverly Hills, California • Sacramento, California • Loveland, Colorado + 26 more
- Conditions
- Cervical Radiculopathy
- Interventions
- CONDUIT Interbody Cervical System with DePuy Synthes Cervical Plating System
- Device
- Lead sponsor
- Research Source
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Biological · Procedure
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Jasper, Alabama