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ClinicalTrials.gov public records Last synced Oct 7, 2026, 10:44 AM EDT

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Showing 49–72 of 254 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Degenerative Joint Disease of Hip Clear all
Completed Not applicable Interventional Results available

Metal on Metal Versus Ceramic on Metal Hip Replacement

NCT00208494
View directory record Official record
Conditions
Non-inflammatory Joint Diseases
Interventions
Total hip replacement
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
20 Years to 75 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
8
States / cities
Little Rock, Arkansas • Orange, California • Palm Bay, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2013 · Synced Oct 7, 2026, 10:44 AM EDT
Completed No phase listed Observational

Outcomes Data of Bone Marrow Stem Cells to Treat Hip and Knee Osteoarthritis

NCT01601951
View directory record Official record
Conditions
Hip and Knee Osteoarthritis
Interventions
Procedural, Bone Marrow concentrate injection
Other
Lead sponsor
Regenerative Pain Center, Illinois
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2014 · Synced Oct 7, 2026, 10:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty

NCT03897595
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
MPact Cup
Device
Lead sponsor
Medacta USA
Industry
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
5
States / cities
Parker, Colorado • Boise, Idaho • Libertyville, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 7, 2026, 10:44 AM EDT
Terminated Phase 4 Interventional

Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty

NCT02299271
View directory record Official record
Conditions
Osteoarthritis of the Hip
Interventions
Ropivacaine, Saline
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Oct 7, 2026, 10:44 AM EDT
Terminated Not applicable Interventional Results available

Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement

NCT02161484
View directory record Official record
Conditions
Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty, Peripheral Nerve Block, Lumbar Plexus Nerve Block, Parasacaral (Sciatic) Nerve Block
Interventions
Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%, Bupivacaine 0.0625%
Procedure · Drug
Lead sponsor
Rita Merman
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Not applicable Interventional

A Prospective, Randomized Trial Comparing Same Day Discharge and Overnight Hospital Stay Among Total Hip Arthroplasties Done by the Direct Anterior Approach

NCT02230657
View directory record Official record
Conditions
Osteoarthritis of the Hip
Interventions
Same day discharge, Next day discharge
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 7, 2026, 10:44 AM EDT
Terminated Phase 4 Interventional

Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System

NCT00546598
View directory record Official record
Conditions
Non-inflammatory Joint Disease, Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Post-traumatic Arthritis
Interventions
Total hip replacement/arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
21 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
6
States / cities
Atlanta, Georgia • Springfield, Illinois • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties

NCT00834483
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
Knotless suture for wound closure, Layered traditional wound closure (monocryl)
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 11, 2014 · Synced Oct 7, 2026, 10:44 AM EDT
Terminated Not applicable Interventional

Total Joint Arthroplasty (TJA) Weight Loss Study

NCT05156762
View directory record Official record
Conditions
Osteoarthritis, Hip, Osteoarthritis, Knee, Obesity, Morbid
Interventions
Bariatric surgery, Medical weight loss, Patient research surveys, Total joint arthroplasty (TJA), Usual standard of care
Procedure · Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Not applicable Interventional

Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement

NCT01373099
View directory record Official record
Conditions
Osteoarthritis, Hip Infection, Prosthetic Joint Infection, Complications; Arthroplasty, Infection or Inflammation, Complications; Arthroplasty
Interventions
Implantation of a static, non-articulating cement spacer., Implantation of an articulating spacer.
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 7, 2026, 10:44 AM EDT
Not listed Not applicable Interventional

On-Table Versus Off-Table Total Hip Arthroplasty

NCT04831372
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip, Osteoarthritis, Hip
Interventions
Off Table Group, On Table Group
Procedure
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2024 · Synced Oct 7, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional

COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL

NCT07532070
View directory record Official record
Conditions
Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
Interventions
Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
Behavioral
Lead sponsor
University of Sydney
Other
Eligibility
18 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Antonio, Nevada • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 7, 2026, 10:44 AM EDT
Terminated No phase listed Observational

Effect of Corticosteroid Injections on Blood Glucose

NCT05048264
View directory record Official record
Conditions
Diabetes Mellitus, Steroid Diabetes, Shoulder Osteoarthritis, Knee Osteoarthritis, Adhesive Capsulitis, Hip Osteoarthritis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 7, 2026, 10:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cooled RF Lesion MRI Characteristics

NCT03631030
View directory record Official record
Conditions
Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis, Arthritis, Degenerative
Interventions
Cooled radiofrequency ablation
Device
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Phase 3 Interventional Results available

A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

NCT00420992
View directory record Official record
Conditions
Osteoarthritis, Chronic Pain
Interventions
ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release), Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
21 Years and older
Enrollment
547 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
81
States / cities
Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 69 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2013 · Synced Oct 7, 2026, 10:44 AM EDT
Recruiting Not applicable Interventional

Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior

NCT07226973
View directory record Official record
Conditions
Osteoarthritis (OA) of the Hip
Interventions
Total hip arthroplasty via direct anterior approach (manual, non-robotic), Total hip arthroplasty via posterior approach (manual, non-robotic), Robotic-assisted total hip arthroplasty via posterior approach
Procedure
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Metairie, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 7, 2026, 10:44 AM EDT
Recruiting No phase listed Observational

Z1 Hip System: Post-Market Clinical Follow Up Study

NCT07104279
View directory record Official record
Conditions
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
Interventions
Z1 Femoral Hip System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
4
States / cities
Charlotte, North Carolina • Cleveland, Ohio • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty

NCT03838874
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
Low-Dose Bupivacaine, Mepivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Days and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Systemic Steroids for Peripheral Nerve Blocks

NCT02464176
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
Dexamethasone, Bupivacaine, Epinephrine, Lumbar Plexus Nerve Block, Saline
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 7, 2026, 10:44 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Outcomes of Robotic Total Hip Arthroplasty

NCT01672320
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 7, 2026, 10:44 AM EDT
Active, not recruiting Not applicable Interventional

Conversations in Health Literacy Using AI Technology for Osteoarthritis Patients

NCT06778486
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis of the Hip or Knee
Interventions
Artificial Intelligence Chatbot
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Not applicable Interventional

Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy

NCT01618097
View directory record Official record
Conditions
Osteoarthritis
Interventions
DVD Decision Aid, Internet Based Decision Aid
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Not applicable Interventional Results available

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)

NCT04533711
View directory record Official record
Conditions
Osteoarthritis
Interventions
OA-PCP Intervention, Attention Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 7, 2026, 10:44 AM EDT
Completed Phase 3 Interventional

A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip

NCT02462850
View directory record Official record
Conditions
Pain, Nausea, Vomiting
Interventions
CL-108
Drug
Lead sponsor
Charleston Laboratories, Inc
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 7, 2026, 10:44 AM EDT