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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Deliberate Self-harm Clear all
Not listed Not applicable Interventional

Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)

NCT04230668
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Borderline Personality Disorder
Interventions
Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Results available

An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART

NCT03838198
View directory record Official record
Conditions
Suicide, Self Harm
Interventions
MI-Enhanced Safety Plan at Hospitalization (1st Component), MI-Enhanced Text Boosters (2nd Component), MI-Enhanced Booster Call (3rd Component)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Phase 2 Interventional Results available

Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents

NCT04005053
View directory record Official record
Conditions
Self-Harm, Depression, Suicide
Interventions
N-acetyl cysteine, Placebo oral tablet
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years to 24 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 25, 2026, 2:36 PM EDT
Recruiting Phase 2 Interventional

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

NCT05304065
View directory record Official record
Conditions
Suicide, Suicidal, Self-Harm
Interventions
SAFETY-A within usual ED Care, Combined SAFETY-A within usual ED Care + CLASP Therapeutic Follow-Up Contacts
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 24 Years
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Sylmar, California • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 25, 2026, 2:36 PM EDT
Withdrawn Not applicable Interventional

College Students Who Self-Harm

NCT02522143
View directory record Official record
Conditions
Borderline Personality Disorder, Suicide
Interventions
Informational sessions describing BPD characteristics, Condensed-DBT treatment intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 27 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional

iKinnect2.0 for Juvenile Justice Involved Youth at Risk for Suicide

NCT04909203
View directory record Official record
Conditions
Child Behavior Disorders, Suicide and Self-harm
Interventions
iKinnect2.0, Active Control App
Device
Lead sponsor
Evidence-Based Practice Institute, Seattle, WA
Industry
Eligibility
15 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Baltimore, Maryland • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial

NCT05202756
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Study Examining Adolescents With Non-Suicidal Self-Injury

NCT02947308
View directory record Official record
Conditions
Self-Injurious Behavior, Deliberate Self-Harm
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 16 Years · Female only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
3
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Recruiting Not applicable Interventional

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

NCT06223867
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self Harm
Interventions
Jaspr App + JAH, ETAU
Device · Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
670 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Suicide Classification System

NCT01118156
View directory record Official record
Conditions
Suicide and Self-harm
Interventions
Education
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Denver, Colorado • Grand Junction, Colorado
Source: ClinicalTrials.gov public record
Updated May 2, 2011 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Lodge First Face Training Evaluation Study

NCT06290180
View directory record Official record
Conditions
Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
Interventions
First Face for Mental Heatlh
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Spokane Valley, Washington
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional

DBT-Based Parenting Intervention for Parents of Youth at Risk for Suicide

NCT04132284
View directory record Official record
Conditions
Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
Interventions
DBT-Based Parenting Intervention, Treatment as Usual
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 18 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Results available

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial

NCT05180383
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents

NCT01111734
View directory record Official record
Conditions
Deliberate Self Harm
Interventions
N-Acetylcysteine, fMRI
Dietary Supplement · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 21 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 25, 2026, 2:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Implementing a Brief Suicide Intervention for High Risk Youth With Front-Line Juvenile Justice Staff

NCT02981420
View directory record Official record
Conditions
Suicide and Self Harm
Interventions
Safety planning
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Systems Aligning for Equity (SAFE) Spaces

NCT05658068
View directory record Official record
Conditions
Suicide, Mental Disorder, Mental Health, Burnout, Professional, Self Harm
Interventions
SAFE Spaces training and coaching
Behavioral
Lead sponsor
New York University
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Recruiting Not applicable Interventional

Telehealth Behavioral Activation for Teens

NCT06273995
View directory record Official record
Conditions
Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild, Depression Moderate, Depression Severe
Interventions
Behavioral Activation
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Treatment for Non-Suicidal Self-Injury in Young Adults

NCT01018433
View directory record Official record
Conditions
Non-suicidal Self-injury
Interventions
T-SIB, Treatment as usual
Behavioral · Other
Lead sponsor
Fordham University
Other
Eligibility
18 Years to 29 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Results available

Suicide Prevention for Justice Involved Managed Care Subscribers

NCT05579600
View directory record Official record
Conditions
Suicide and Self-harm
Interventions
Caring Contacts letters
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
45,155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional

Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial

NCT05180331
View directory record Official record
Conditions
Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Home-Based Mental Health Evaluation (HOME)

NCT03347552
View directory record Official record
Conditions
Suicide and Self-harm
Interventions
HOME
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Portland, Oregon • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Phase 4 Interventional Results available

Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder

NCT00533117
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Fluoxetine, Dialectical Behavior Therapy, Supportive psychotherapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth

NCT03709472
View directory record Official record
Conditions
Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation, Family Relations
Interventions
Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
11 Years to 18 Years
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Sep 25, 2026, 2:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks

NCT03375099
View directory record Official record
Conditions
Intentional Self-Harm by Other Specified Means
Interventions
Lethal Means Counseling, Health and Stress Reduction
Behavioral
Lead sponsor
University of Southern Mississippi
Other
Eligibility
18 Years to 60 Years
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Sep 25, 2026, 2:36 PM EDT