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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 3,004 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dementia Clear all
Enrolling by invitation No phase listed Observational

Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders

NCT04680130
View directory record Official record
Conditions
PSP, CBD, PCA, LPA, Semantic Dementia, Semantic Aphasia, Behavioral Variant of Frontotemporal Dementia, FTD, PPA, Apraxia of Speech, MSA - Multiple System Atrophy, Parkinson Disease
Interventions
C-11 PiB, AV1451 Tau, C-11 ER176
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2050
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 23, 2026, 8:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias

NCT01730430
View directory record Official record
Conditions
Alzheimer's Disease, Dementias
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
55 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2014 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Metabolic Cerebral Imaging in Incipient Dementia (MCI-ID)

NCT00329706
View directory record Official record
Conditions
Dementia
Interventions
FDG-PET brain scan
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
710 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2017
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Santa Monica, California + 5 more
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Phase 4 Interventional

Repetitive Transcranial Magnetic Stimulation for Apathy in Alzheimer's Dementia

NCT02190084
View directory record Official record
Conditions
Apathy, Alzheimer's Dementia
Interventions
Neurostar repetitive transcranial magnetic stimulator
Device
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
55 Years to 91 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Oct 23, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

NCT05907343
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Dementia (AD)
Interventions
Closed-loop TBS, Open-loop TBS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Dietary Treatments for Cognitive Impairment in Older Adults

NCT02521818
View directory record Official record
Conditions
Mild Cognitive Impairment, Probable Alzheimer's Disease
Interventions
Modified Atkins Diet, NIA Diet for Seniors
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 23, 2026, 8:23 PM EDT
Recruiting No phase listed Observational

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

NCT05658913
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
AV-1451
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 120 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Enrolling by invitation No phase listed Observational

F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)

NCT02414178
View directory record Official record
Conditions
Alzheimer Disease
Interventions
F 18 T807
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil

NCT00829374
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Dimebon, Placebo comparator
Drug
Lead sponsor
Medivation, Inc.
Industry
Eligibility
50 Years and older
Enrollment
1,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
52
States / cities
Phoenix, Arizona • Sun City, Arizona • Tucson, Arizona + 49 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Phase 1 Interventional Results available

Elpipodect (MK-8189) Safety and Tolerability in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis (MK-8189-017)

NCT05227118
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Elpipodect, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
65 Years to 85 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Santa Ana, California • Cutler Bay, Florida • Hallandale, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional Results available

Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia

NCT01363258
View directory record Official record
Conditions
Care-resistant Behavior, Dementia
Interventions
Care-resistant mouth care (MOUTh), Evidence-based mouth care
Behavioral · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Bellefonte, Pennsylvania • Harrisburg, Pennsylvania • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional Results available

Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients

NCT03325608
View directory record Official record
Conditions
Dementia
Interventions
POISED Care
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
75 Years and older
Enrollment
889 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional Results available

Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury

NCT04073225
View directory record Official record
Conditions
Traumatic Brain Injury, Dementia Alzheimers, Military Activity
Interventions
MindPod Dolphin, 10 Keys to Healthy Aging
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 23, 2026, 8:23 PM EDT
Recruiting Phase 2 Interventional

Alzheimer's Tau Platform: Master Protocol

NCT06957418
View directory record Official record
Conditions
Preclinical Alzheimer's Disease, Alzheimer Disease, Prodromal Alzheimer's Disease
Interventions
AADvac1, Tau2
Drug
Lead sponsor
Paul S. Aisen
Other
Eligibility
50 Years to 80 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
San Francisco, California • Providence, Rhode Island • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Active, not recruiting Not applicable Interventional

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms in Hispanic Individuals

NCT06099197
View directory record Official record
Conditions
Caregiver Burden, Alzheimer Disease
Interventions
Brain CareNotes, Dementia Guide Expert
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Fluselenamyl - Beta Amyloid PET Imaging for Alzheimer Disease

NCT05731440
View directory record Official record
Conditions
Alzheimer Disease
Interventions
18F-Fluselenamyl
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Recruiting Not applicable Interventional

OTC Hearing Aid and MCI

NCT06112860
View directory record Official record
Conditions
Hearing Loss, Mild Cognitive Impairment, Alzheimer Disease and Related Dementias (ADRD)
Interventions
Over the counter hearing aid, Communication Strategies Information/Counseling
Device · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Evanston, Illinois • La Crosse, Wisconsin • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE)

NCT00040378
View directory record Official record
Conditions
Alzheimer Disease
Interventions
alphatocopherol, Selenium, Placebo replacement for vitamin E, Placebo replacement for Selenium
Drug
Lead sponsor
Frederick Schmitt
Other
Eligibility
60 Years to 90 Years · Male only
Enrollment
4,246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2016
U.S. locations
84
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chula Vista, California + 70 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Comparing Smartphone Technology and a Memory Strategy on Improving Prospective Memory in Alzheimer's Disease

NCT03384043
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Impairment, Mild, Dementia, Mild
Interventions
Smartphone Personal Assistant, Implementation Intention
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional

Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease

NCT02268617
View directory record Official record
Conditions
Huntington Disease, Lewy Body Disease
Interventions
Treadmill Walking
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Triglyceride Effects on Blood Flow in the Human Brain

NCT05218018
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lipid drink
Dietary Supplement
Lead sponsor
University of Washington
Other
Eligibility
55 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 23, 2026, 8:23 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Preparing Successful Aging Through Dementia Literacy Education And Navigation (PLAN)-Home

NCT05225818
View directory record Official record
Conditions
Dementia
Interventions
PLAN - Home
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 23, 2026, 8:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sight and Hearing Investigation Into Effects on Delirium

NCT06176625
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium, Delirium in Old Age, Delirium of Mixed Origin, Delirium With Dementia, Delirium on Emergence, Delirium, Cause Unknown, Delirium Superimposed on Dementia, Delirium Confusional State, Delirium;Non Alcoholic, Hearing Loss, Bilateral, Hearing Loss, Sensorineural, Hearing Loss, Functional, Hearing Loss, High-Frequency, Hearing
Interventions
Communication Signage, Amplifier Use
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 23, 2026, 8:23 PM EDT
Completed Phase 2 Interventional Results available

Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia With Lewy Bodies

NCT04001517
View directory record Official record
Conditions
Dementia With Lewy Bodies (DLB)
Interventions
Neflamapimod
Drug
Lead sponsor
EIP Pharma Inc
Industry
Eligibility
55 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
22
States / cities
La Jolla, California • Santa Monica, California • Aurora, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 23, 2026, 8:23 PM EDT