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Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Accepts healthy volunteers Results available

Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty

NCT02493621
Conditions
Arthropathy of Hip
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Anesthesia
Interventions
Tetracaine HCl 3% and oxymetazoline HCl 0.05%, Tetracaine HCl 3%, Placebo
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
3
States / cities
Baltimore, Maryland • Salt Lake City, Utah
Conditions
Anesthesia
Interventions
Dexmedetomidine, Midazolam, Fentanyl, Morphine
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
28 Weeks to 36 Weeks
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Louisville, Kentucky • Pittsburgh, Pennsylvania • Greenville, South Carolina + 1 more
Conditions
Educational Problems
Interventions
Biplane Ultrasound, Single plane ultrasound
Other
Lead sponsor
University of Florida
Other
Eligibility
4 Months to 10 Years · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Arthroplasty, Replacement, Knee
Interventions
Femoral nerve catheter and sciatic nerve block, Adductor canal catheter and selective tibial block, Adductor canal catheter only
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Dental Anesthesia, Anesthesia, Local, Anesthesia, Reversal
Interventions
OraVerse, Sham injection
Drug · Other
Lead sponsor
Novocol Pharmaceutical of Canada, Inc.
Industry
Eligibility
2 Years to 5 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
7
States / cities
San Francisco, California • Indianapolis, Indiana • Columbus, Ohio + 4 more
Not listed Phase 4 Interventional Accepts healthy volunteers

Vibratory Anesthesia in Trigger Finger Injections

NCT05405452
Conditions
Trigger Finger, Pain, Anesthesia, Local
Interventions
Vibration Anesthesia Device by Blaine Labs, Gebauers Ethyl Chloride 100% Topical Spray
Device · Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Tucson, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Preparing Children for Anesthesia With an Educational Pop-Up Book

NCT04796077
Conditions
Pediatric Preoperative Anxiety, Pediatric Coping
Interventions
Pop-Up Book
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
5 Years to 12 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Duluth, Georgia
Conditions
Anesthesia
Interventions
HSK3486, Propofol
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
13
States / cities
Phoenix, Arizona • Pasadena, California • Tamarac, Florida + 10 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery

NCT00659945
Conditions
Postoperative Nausea and Vomiting
Interventions
Aprepitant plus Ondansetron, Ondansetron plus placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
Virtua Health, Inc.
Other
Eligibility
18 Years to 85 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Mount Holly, New Jersey
Conditions
Anesthesia, Sedation, Endoscopy
Interventions
Remimazolam, Propofol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Anesthesia, Dental, Pain, Postoperative
Interventions
lidocaine, articaine
Drug
Lead sponsor
Boston University
Other
Eligibility
4 Years to 14 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Phase 4 Interventional Accepts healthy volunteers

Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel

NCT00846690
Conditions
Dental Pain, Postoperative Pain
Interventions
benzocaine, TAC alternate gel
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
6655 Travis Suite 460, Texas
Conditions
Kidney Transplant; Complications, Postoperative Residual Curarization, Postoperative Residual Weakness
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment

NCT03799484
Conditions
Forehead Rhytides, Forehead Wrinkles
Interventions
Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Anesthesia, Surgery, Knee Arthropathy
Interventions
Nonpharmacologic Treatment, Standard Care
Other
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Prostate Cancer
Interventions
low venous pressure general anesthesia, combined spinal-epidural anesthesia
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Conditions
Regional Anesthesia
Interventions
The ScanNav, a novel artificial intelligence device designed to assist in Ultrasound guided regional anesthesia
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
20 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis

NCT01951820
Conditions
Anesthesia of Mucous Membrane
Interventions
Pliaglis, Benzocaine, Articaine
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Drug Reaction to Analgesic Nos
Interventions
RX0041 4%, Placebo, RX0041 8%
Drug
Lead sponsor
Pharmaceutical Project Solutions, Inc.
Industry
Eligibility
18 Years and older
Enrollment
648 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Mount Arlington, New Jersey • Columbia, South Carolina
Conditions
Pain
Interventions
S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%), Placebo Peel
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Clinton Township, Michigan • New York, New York
Conditions
Ankle Fractures
Interventions
Regional anesthesia group, Local multimodal analgesia group
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
2
States / cities
Salt Lake City, Utah
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Nanodropper-mediated Topical Anesthetic

NCT06636708
Conditions
Corneal Diseases, Effectiveness of Microdrops
Interventions
Nanodropper and Proparacaine HCl 0.5%, Standard Eye Drop Bottle with Proparacaine HCl 0.5%
Combination Product
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York