Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 5:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 60 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dentin Sensitivity Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity

NCT02293044
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Crest® Sensi-Stop™ Strips
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity

NCT02406573
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Crest® Sensi-Stop™ Strips
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Results available

A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste

NCT04964063
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium Nitrate + Sodium Fluoride
Other
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
655 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NUPRO Sensodyne Prophylaxis Paste With NovaMin Sensitivity Relief Study

NCT01669785
View directory record Official record
Conditions
Tooth Hypersensitivity
Interventions
Group C, Group A, Group B
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 70 Years
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Phase 4 Interventional Results available

Dose Response of a Tubule Occlusion Agent

NCT01075256
View directory record Official record
Conditions
Dentine Hypersensitivity, Dental Pain
Interventions
5% calcium sodium phosphosilicate toothpaste, 7.5% calcium sodium phosphosilicate toothpaste, Placebo toothpaste
Device
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 50 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes

NCT02513212
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium Oxalate, Stannous fluoride paste, Manual toothbrush, Power toothbrush
Device · Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

The Efficacy of a Toothpaste to Reduce Sensitivity

NCT00763269
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
12 Years to 80 Years
Enrollment
626 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Cedar Knolls, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 28, 2026, 5:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion

NCT04006470
View directory record Official record
Conditions
Enamel Erosion
Interventions
Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity

NCT02476032
View directory record Official record
Conditions
Tooth Sensitivity
Interventions
Prof applied oxalate, Self applied oxalate, Prof applied placebo
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2017 · Synced Oct 28, 2026, 5:10 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety Assessment of Experimental Bleaching Agents

NCT06802614
View directory record Official record
Conditions
Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
Interventions
BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B, VISIBLE LIGHT IRRADIATION, Whiteness HP 35%, Whiteness HP Automixx 6%
Device · Radiation
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.

NCT02651467
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5), Placebo Oral Rinse (0% w/w KOX 0ppm F, pH 4.5 )
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NUPRO(r) Sensodyne Prophylaxis Paste With NovaMin(r)Sensitivity Relief Study

NCT01610167
View directory record Official record
Conditions
Tooth Hypersensitivity
Interventions
NUPRO Classic Prophy Paste, NUPRO Sensodyne Prophy Paste with Novamin with fluoride., NUPRO Sensodyne Prophy Paste with Novamin without fluoride.
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 70 Years
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2013 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

NCT02192307
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium oxalate
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Oct 28, 2026, 5:10 PM EDT
Terminated Not applicable Interventional

Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations

NCT07261137
View directory record Official record
Conditions
Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
Interventions
Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
7 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Results available

A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management

NCT06045026
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Stannous fluoride
Other
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
536 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 28, 2026, 5:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation of OBU When Used for Indirect Dental Restorations

NCT06002880
View directory record Official record
Conditions
Sensitivity, Tooth
Interventions
Optibond Universal
Device
Lead sponsor
Kerr Corporation
Industry
Eligibility
18 Years to 100 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

NCT02542943
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Experimental Oral Rinse 1, Experimental Oral Rinse 2, Placebo Oral Rinse, Standard fluoride toothpaste
Device · Other · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Phase 2 Interventional

Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity

NCT06464939
View directory record Official record
Conditions
Dentin Hypersensitivity
Interventions
KH001, Placebo
Drug
Lead sponsor
HysensBio Co., Ltd
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity

NCT04590040
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Placebo, 15% nano-HAP toothpaste, 5% KNO3 toothpaste
Other · Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
20 Years to 80 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)

NCT02937623
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Dissolvable polymer strip containing Novamin (calcium sodium phosphosilicate)
Device
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene

NCT02221349
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium oxalate, Sodium fluoride paste, Stannous fluoride paste
Device · Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity.

NCT07149376
View directory record Official record
Conditions
Sensitivity, Tooth
Interventions
TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste
Device · Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Costa Mesa, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Not applicable Interventional Results available

Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®

NCT00881959
View directory record Official record
Conditions
Gingival Recession
Interventions
Puros® Dermis versus Alloderm®
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
4
States / cities
Birmingham, Alabama • Ann Arbor, Michigan • Newark, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 28, 2026, 5:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity

NCT01592864
View directory record Official record
Conditions
Dentine Hypersensitivity
Interventions
Stannous Fluoride, Sodium Monofluorophosphate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Oct 28, 2026, 5:10 PM EDT