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ClinicalTrials.gov public records Last synced Nov 5, 2026, 8:06 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1081–1104 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Major Depressive Disorder
Interventions: Active NeuroStar® Transcranial Magnetic Stimulation (TMS), Sham NeuroStar® Transcranial Magnetic Stimulation (TMS); Device
Lead sponsor: Neuronetics; Other
Eligibility: 12 Years to 21 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 13
States / cities: Dothan, Alabama • Los Angeles, California • Palo Alto, California + 10 more

Conditions: Problem Behaviors, Attention Deficit Hyperactivity Disorder, Depression
Interventions: Attachment and Biobehavioral Catch-up, Developmental Education for Families; Behavioral
Lead sponsor: University of Delaware; Other
Eligibility: 20 Months to 36 Months
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2016
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety
Interventions: Whole Selves; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bipolar Depression
Interventions: CoEnzyme Q10; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 55 Years to 89 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Postpartum Depression
Interventions: WB001, Educational; Device
Lead sponsor: Woebot Health; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, Anxiety Disorders, Stress Related Disorder
Interventions: Not listed
Lead sponsor: Singula Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2032
U.S. locations: 1
States / cities: New York, New York

Conditions: Bipolar Disorder
Interventions: JNJ-55308942, Placebo; Drug
Lead sponsor: Janssen Pharmaceutica N.V., Belgium; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 18
States / cities: Huntsville, Alabama • Little Rock, Arkansas • Lemon Grove, California + 15 more

Conditions: Depression
Interventions: Psilocybin (Usona Institute); Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Alcoholism, Depression
Interventions: NALTREXONE, Placebo; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 55 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2005
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression, Involutional
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Major Depression With Psychotic Features
Interventions: quetiapine; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Major Depressive Disorder
Interventions: Pramipexole; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 50 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Schizophrenia Spectrum and Other Psychotic Disorders, Schizophrenia, Delusional Disorder, Bipolar 1 Disorder, Schizoaffective Disorder, Psychosis Not Otherwise Specified, Early Psychosis
Interventions: Not listed
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 6
States / cities: Hartford, Connecticut • Athens, Georgia • Chicago, Illinois + 3 more

Conditions: Postoperative Pain, Nausea, Vomiting, Anxiety, Depression
Interventions: Acupuncture; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 238 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, ESRD
Interventions: Not listed
Lead sponsor: Portland VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Stress, Anxiety, Depression, Psychological Distress, Mindfulness
Interventions: AI-Enabled Mobile App-Based Mindfulness Intervention; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 60 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Tampa, Florida

Conditions: Suicidal Ideation, Suicidal and Self-injurious Behavior, Depression
Interventions: iCHART/cASAP, Treatment as usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years to 17 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Itasca, Illinois

Conditions: Bipolar Disorder, Mood Disorder, Unipolar Depression
Interventions: Magstim Super Rapid Magnetic Stimulator, Cadwell MES-10; Device
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 90 Years
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 2006
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Bipolar Disorder, Bipolar Depression, Unipolar Depression
Interventions: Lithium, Lamotrigine; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Stress, Caregiver Burden, Anxiety, Depressive Symptoms
Interventions: Self-Compassion Based Resilient Caregiving Course; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Depression, Traumatic Brain Injury
Interventions: aerobic exercise, stretching and flexibility program; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 14 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Posttraumatic Stress Disorder
Interventions: Pregnenolone, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Major Depressive Disorder
Interventions: active tVNS, Sham tVNS; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 50 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Functional Disability, Dementia, Heart Disease, Stroke, Cancer, Bleeding, Depression
Interventions: 100 mg enteric-coated aspirin, Placebo; Drug
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 65 Years and older
Enrollment: 19,114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2024
U.S. locations: 33
States / cities: Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 26 more

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Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents

Mental Health Services for Foster and Adopted Children

Whole Selves User Testing and Feasibility Study

CoQ10 in Geriatric Bipolar Depression

Pivotal Test: WB001

An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

A Study of JNJ-55308942 in the Treatment of Bipolar Depression

Psilocybin-Assisted Therapy as a Treatment for Depression

Treating Alcohol Use In Older Adults With Depression

Neurocardiac Control in Major Depression

Treatment of Depression With Quetiapine

Imaging Dopamine Release in Depression

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

Pragmatic Research eXamining Inpatient Symptoms

Morbidity and Mortality Among Dialysis Patients After Treatment for Depression

Mobile Application Mindfulness

Optimizing Suicide Prevention Strategies for Pediatric Primary Care

Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders

PET and MRI Brain Imaging of Bipolar Disorder

Self-Compassion to Enhance the Well-Being of Caregivers of Children With Physical Disabilities

Exercise Training in Depressed Traumatic Brain Injury Survivors

Neurosteroids for Treatment of PTSD in Veterans

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Aspirin in Reducing Events in the Elderly