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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:41 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1513–1536 of 4,844 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Depressed Clear all

Conditions: Depression, Anxiety, Burnout, Student
Interventions: Mindfulness Practice, Storytelling Workshop; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Major Depressive Disorder
Interventions: Behavioral activation plus mobile app, Standard behavioral activation; Behavioral
Lead sponsor: Central Arkansas Veterans Healthcare System; Federal
Eligibility: 18 Years to 89 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: North Little Rock, Arkansas

Conditions: Depression, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions: Collaborative care, Interview or Focus Group, Media/technology Intervention with collaborative care, Survey Administration; Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 297 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 4
States / cities: Auburn, Washington • Gig Harbor, Washington • Seattle, Washington + 1 more

Conditions: Cardiovascular Diseases, Coronary Disease, Heart Diseases, Depression
Interventions: Psychoeducation; Treatment recommendations, Pharmacotherapy, Usual Care; Behavioral · Drug · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 100 Years
Enrollment: 453 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Perinatal Problems, Post Traumatic Stress Disorder, Post Partum Depression
Interventions: PTSD Psychoeducation + Skills Intervention; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Post-stroke Depression
Interventions: Transcranial Electrical stimulation, Transcutaneous direct current stimulation; Procedure
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Breast Cancer, Depression, Fatigue, Sleep Disorders
Interventions: Yoga, Education; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Anxiety, Depression, Depression, Anxiety, Anxiety Disorders
Interventions: Acceptance and Commitment Therapy (ACT), Reflective Journaling; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Major Depressive Disorder, Major Depression, Unipolar Depression
Interventions: fluoxetine or desipramine; Drug
Lead sponsor: National Institute of General Medical Sciences (NIGMS); NIH
Eligibility: 18 Years to 70 Years
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2008
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Depression
Interventions: Guanfacine, Sertraline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Palo Alto, California • Chicago, Illinois

Conditions: Depression, Unipolar
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Major Depressive Disorder
Interventions: BCI-024: over-encapsulated Buspirone tablet 15 mg QD and BCI-049: over-encapsulated Melatonin tablet 3 mg QD, BCI-024 (Buspirone), Matching placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 9
States / cities: Garden Grove, California • San Diego, California • Altanta, Georgia + 6 more

Conditions: Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder, Sleep Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1997 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Autism Spectrum Disorder, Depression, Anxiety
Interventions: Cognitive-Behavioral Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Charlottesville, Virginia

Conditions: Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions: Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS); Behavioral
Lead sponsor: University of New Hampshire; Other
Eligibility: 18 Years to 24 Years
Enrollment: 1,268 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Durham, New Hampshire

Conditions: Treatment Resistant Depression
Interventions: BPL-003; Drug
Lead sponsor: Beckley Psytech Limited; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 19
States / cities: Birmingham, Alabama • Rogers, Arkansas • San Diego, California + 15 more

Conditions: Depression
Interventions: Ketamine; Drug
Lead sponsor: Neurological Associates of West Los Angeles; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Stress
Interventions: Cognitive Based Compassion Training Session: Developing Attention and Stability of Mind, Cognitive Based Compassion Training Session: Cultivating Insight into the Nature of Mental Experience, Cognitive Based Compassion Training Session: Self-compassion, Cognitive Based Compassion Training Session: Cultivating Equanimity, Cognitive Based Compassion Training Session: Developing Appreciation and Gratitude for Others, Cognitive Based Compassion Training Session: Developing Affection and Empathy, Cognitive Based Compassion Training Session: Realizing Wishing and Aspiring Compassion, Cognitive Based Compassion Training Session: Realizing Active Compassion, Meditation Session; Behavioral
Lead sponsor: Emory University; Other
Eligibility: Not listed
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Breast Cancer, Depression, Long-term Effects of Cancer Treatment, Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Interventions: educational intervention, informational intervention, internet-based intervention, questionnaire administration, study of socioeconomic and demographic variables, survey administration, psychosocial assessment and care, quality-of-life assessment; Other · Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: Not listed
Enrollment: 1,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 3
States / cities: Miami, Florida • New York, New York • Seattle, Washington

Conditions: Neuroinflammatory Diseases, Multiple Sclerosis
Interventions: Exercise Training, Mobility and Flexibility Training; Behavioral
Lead sponsor: The Hospital for Sick Children; Other
Eligibility: 11 Years to 25 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: La Jolla, California • Philadelphia, Pennsylvania

Conditions: Depression, Anxiety
Interventions: Image Narrative; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 29 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Depression, Postpartum Depression
Interventions: Mothers and babies Internet course and PPD informational brochure; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Bipolar Depression
Interventions: Lumateperone, Placebo; Drug · Other
Lead sponsor: Intra-Cellular Therapies, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 381 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 14
States / cities: Birmingham, Alabama • Sherman Oaks, California • Miami, Florida + 11 more

Conditions: Major Depressive Disorder (MDD), Suicidal Ideation
Interventions: TMS; Device
Lead sponsor: University of California, Davis; Other
Eligibility: 15 Years to 25 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Sacramento, California

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Storytelling and Mindfulness for Graduate Student Wellbeing

Mobile Apps for the Treatment of Depression

Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE

Effectiveness of Depression Treatment Following Coronary Artery Bypass Surgery

Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women

Developing an EEG Probe for Studying and Modulating Cognitive Control

Yoga or Educational Wellness Class for Women With Stage I, Stage II, or Stage III Breast Cancer Undergoing Chemotherapy

Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons

Antidepressant Treatment of Mexican-Americans: UCLA Pharmacogenetics and Pharmacogenomics Research Group

ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

Machine Learning to Predict Clinical Response to TMS

Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD)

Consequences of Conjugal Bereavement in Adults

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

BPL-003 Efficacy and Safety in Treatment Resistant Depression

Intravenous Ketamine Effects on Functional Neuroanatomy

CBCT for Parents of Children With Autism

Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer

FIT-ATOMIC Exercise Feasibility Trial

Image Narrative With College Students

Effectiveness of a Web-based Prevention Program for Postpartum Depression

Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted Globally

Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk