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Showing 1–24 of 460 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

NCT03640325
View directory record Official record
Conditions
Cancer, Bone Marrow Neoplasms, Anxiety, Depression, Quality of Life, Adherence, Medication, Coping Skills, Adolescent Behavior
Interventions
PRISM (Promoting Resilience in Stress Management)
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
12 Years to 24 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
5
States / cities
Birmingham, Alabama • Los Angeles, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 3 Interventional Results available

A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD

NCT01372150
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
desvenlafaxine succinate sustained release, fluoxetine, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
7 Years to 17 Years
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
41
States / cities
Dothan, Alabama • Goodyear, Arizona • Tucson, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 2 Interventional Results available

Omega-3 Fatty Acids in Adolescent Depression

NCT00312897
View directory record Official record
Conditions
Adolescent Depression
Interventions
Omega-3 Fatty Acids, corn oil
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
12 Years to 19 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2)

NCT01490307
View directory record Official record
Conditions
Substance Use, Conduct Disorder, Depression, Anxiety
Interventions
Family Check-Up
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 11, 2011 · Synced Sep 3, 2026, 10:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Advocates for All Youth

NCT05025657
View directory record Official record
Conditions
Depression, Anxiety, Self Efficacy, Suicidal Ideation
Interventions
ALLY
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
9 Years to 14 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Loachapoka, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 3, 2026, 10:24 AM EDT
Terminated Not applicable Interventional

Evaluating a Tailored Cognitive Behavioral Therapy for Adolescent and Young Adult Cancer Patients

NCT04773197
View directory record Official record
Conditions
Depression, Anxiety, Cancer
Interventions
Beating the Blues (BtB), Entertain Me Well (EMW), Coaching
Behavioral
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
15 Years to 25 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 3 Interventional

Omega-3 Fatty Acids for Treatment of Depression in Adolescents

NCT00658476
View directory record Official record
Conditions
Depression
Interventions
Fish Oil, Cognitive Behavior Therapy, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years to 21 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2012 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

School-Based Depression Prevention for Adolescents With ADHD

NCT04104841
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Depressive Symptoms
Interventions
Behaviorally Enhancing Adolescents' Mood in Schools, Usual Care
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
14 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Depression Prevention Program for American Indian Adolescents During and After Pregnancy

NCT00183547
View directory record Official record
Conditions
Depression, Pregnancy
Interventions
"Living in Harmony" depression prevention program, Depression-prevention education and support
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
15 Years to 19 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
2
States / cities
Whiteriver, Arizona • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram

NCT00851006
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Creatine Monohydrate
Drug
Lead sponsor
University of Utah
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Sequential Treatment of Pediatric MDD to Increase Remission and Prevent Relapse

NCT00612313
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine, Relapse prevention cognitive behavioral therapy (CBT)
Drug · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 17 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 1 Interventional

Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders

NCT00438685
View directory record Official record
Conditions
Substance-Related Disorders, Depressive Disorder, Anxiety Disorder
Interventions
Outpatient MST/OPTION-A, Usual Services
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2

NCT05267340
View directory record Official record
Conditions
Depression Mild, Depression Moderate, Depression, Teen
Interventions
TARA, Psycho-Education
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

CBT Insomnia Teens: Augmenting SSRIs to Improve Youth Depression

NCT02290496
View directory record Official record
Conditions
Insomnia, Depression
Interventions
CBT for Insomnia (CBT-I), Sleep Hygiene (SH)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 19 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 16, 2018 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

Development of an Insomnia Treatment for Depressed Adolescents

NCT02163564
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 19 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 3, 2026, 10:24 AM EDT
Recruiting Not applicable Interventional

Teen Recovery Through Inspiration, Support, and Empowerment

NCT07170657
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
Interventions
Peer Support Services Recovery
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 3, 2026, 10:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mental Health in Primary Care

NCT05426057
View directory record Official record
Conditions
Depression, Anxiety, Suicide, Drug Use
Interventions
eHealth Familias Unidas Mental Health
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 16 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
17
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression

NCT03363919
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
NeuroStar TMS Therapy® System, NeuroStar XPLOR®
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional Results available

Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms

NCT05317481
View directory record Official record
Conditions
Bipolar Disorder, Major Depressive Disorder, Mood Disorders, Suicide, Suicidal Ideation
Interventions
BE-SMART-DR, psychoeducational control comparator condition (CC)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 29 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 10:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating an Online Wellness Intervention for Greek Adolescents

NCT04815681
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Happiness
Interventions
Common Elements Toolbox, Active Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 20 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

A Mobile Health Solution for Homework During CBT

NCT04931199
View directory record Official record
Conditions
Anxiety, Depression, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy (CBT), CBT+App
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 3, 2026, 10:24 AM EDT
Recruiting Not applicable Interventional

CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

NCT05456035
View directory record Official record
Conditions
Depression
Interventions
Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
13 Years to 17 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Phase 3 Interventional

A Double-Blind Randomized Placebo Controlled Study of Quetiapine for the Treatment of Depression in Adolescents With Bipolar Disorder

NCT00232414
View directory record Official record
Conditions
Bipolar I Disorder
Interventions
Quetiapine
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Sep 3, 2026, 10:24 AM EDT
Completed Not applicable Interventional

The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome

NCT03192540
View directory record Official record
Conditions
Down Syndrome
Interventions
Exercise
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 3, 2026, 10:24 AM EDT