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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:37 PM EDT

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Showing 2449–2472 of 5,335 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression Clear all
Completed Not applicable Interventional Results available

Neuromodulation for Comorbid Hoarding Disorder and Depression

NCT05985356
View directory record Official record
Conditions
Hoarding Disorder, Hoarding, Depression
Interventions
iTBS
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 30, 2026, 10:37 PM EDT
Active, not recruiting Not applicable Interventional

AI Mental Health Tool vs. Psychoeducation Control

NCT07841483
View directory record Official record
Conditions
Depressive Disorder, Depressive Symptoms
Interventions
Ash, Brief Therapist-Delivered Telehealth
Behavioral
Lead sponsor
Slingshot AI
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 10:37 PM EDT
Terminated Not applicable Interventional Results available

Radiosurgical Neuromodulation for Refractory Depression

NCT01403441
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Radiosurgical Neuromodulation using the Cyberknife
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 2 Interventional Results available

Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.

NCT02185131
View directory record Official record
Conditions
Major Depressive Disorder, Alcohol Use Disorder
Interventions
Mirtazapine, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Quest to Analyze One Thousand Humans Meditating

NCT06583395
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma, Atrial Fibrillation, Cancer Brain, Cancer, Breast, Cancer Colon, Cancer, Lung, Cancer, Ovarian, Cancer Prostate, Cancer Skin, Throat Cancer, Lymphoma, Cancer, Thyroid, Cancer, Other, Cerebral Palsy, Chronic Fatigue Syndrome, Cluster Headache, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Diseases, Crohn Disease, Deafness, Depression, Diabetes, Eczema, Epilepsy, Fibroids, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Irritable Bowel Syndrome (IBS), Infertility, Lyme Disease, Macular Degeneration, Migraine, Multiple Allergies, Multiple Sclerosis, Osteoarthritis, Osteoporosis, Ovarian Cysts, Parkinson Disease, Phantom Limb Pain, Psoriasis, Post Traumatic Stress Disorder (PTSD), Rheumatoid Arthritis, Sjogrens Disease, Spinal Cord Injury, Spinal Stenosis, Stroke, Tension Headache, Tinnitus, Ulcerative Colitis
Interventions
Advanced multi-component meditation practice
Behavioral
Lead sponsor
Tobias Moeller-Bertram
Industry
Eligibility
21 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Palm Desert, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder

NCT03716869
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Episode
Interventions
Universal Screening Arm
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
12,909 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 30, 2026, 10:37 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Antagonism of Opioid-Induced Respiratory Depression by CX1739 With Preservation of Opioid Analgesia

NCT02735629
View directory record Official record
Conditions
Opiate Induced Respiratory Depression
Interventions
CX1739 - 300 mg, CX1739 - 600 mg, CX1739 - 900 mg, Placebo
Drug
Lead sponsor
RespireRx
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2016 · Synced Oct 30, 2026, 10:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Prison Inmates' Attitudes and Internal Emotional States

NCT04374357
View directory record Official record
Conditions
Forgiveness
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Male only
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Portage, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 30, 2026, 10:37 PM EDT
Terminated Not applicable Interventional Results available

Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression

NCT06219681
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Active neurofeedback, Sham neurofeedback
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 35 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 3 Interventional Results available

A Study in the Treatment of Children and Adolescents With Major Depressive Disorder

NCT00849901
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
duloxetine, Placebo, fluoxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
7 Years to 17 Years
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
24
States / cities
Costa Mesa, California • Irvine, California • Palo Alto, California + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Reducing Depression Self-stigma and Increasing Treatment Seeking Intentions Among Youth

NCT06172075
View directory record Official record
Conditions
Stigma, Social, Mental Health Disorder, Depression
Interventions
Brief video intervention (Black Woman), Brief video intervention (Latinx Woman), Brief video intervention (White Woman), Vignette Control
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 25 Years
Enrollment
1,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 2 Interventional Results available

OnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult Females

NCT02116361
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
onabotulinumtoxinA, Normal Saline
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
35
States / cities
Little Rock, Alaska • Bellflower, California • Cerritos, California + 29 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 2 Interventional Results available

Study to Treat Major Depressive Disorder With a New Medication

NCT03043560
View directory record Official record
Conditions
Depressive Disorder, Anhedonia
Interventions
Ezogabine, Placebos
Drug
Lead sponsor
James Murrough
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2020 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Healthy Minds Comparison Study

NCT06282523
View directory record Official record
Conditions
Depression, Anxiety, Depression/Anxiety
Interventions
HMP app, HMRP web app
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 30, 2026, 10:37 PM EDT
Completed No phase listed Observational

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 1 Interventional

Teen Depression Awareness Project (TDAP)

NCT00099827
View directory record Official record
Conditions
Depression
Interventions
Education
Behavioral
Lead sponsor
RAND
Other
Eligibility
13 Years to 17 Years
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
8
States / cities
Los Angeles, California • San Fernando, California • Washington D.C., District of Columbia + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2011 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 1 Interventional

Community-Based Integrated Treatment for Adolescents

NCT01667159
View directory record Official record
Conditions
Depression, Alcohol Use
Interventions
Integrated Cognitive Behavioral Therapy, Standard Care
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional Results available

The Safety and Efficacy of Nexalin Trans-cranial Electrical Stimulation Stimulation for the Treatment of Depression

NCT03277846
View directory record Official record
Conditions
Depression
Interventions
Nexalin Based Trans-Cranial Electrical Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Belle Mead, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Oct 30, 2026, 10:37 PM EDT
Completed No phase listed Observational

Treatment Outcome of Vascular Depression

NCT00045773
View directory record Official record
Conditions
Depressive Disorder, Depression
Interventions
Sertraline
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
60 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
2
States / cities
St Louis, Missouri • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Phase 2Phase 3 Interventional Results available

SAM-e for the Treatment of Depression in Patients With Parkinson's Disease

NCT00070941
View directory record Official record
Conditions
Parkinson's Disease, Depression
Interventions
SAM-e, oral escitalopram, placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
30 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2016 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Art Therapy in Obstetric Patients

NCT05503056
View directory record Official record
Conditions
Pregnancy Related, Depression
Interventions
art therapy, nothing
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 30, 2026, 10:37 PM EDT
Completed Not applicable Interventional

Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar

NCT01520129
View directory record Official record
Conditions
Bipolar Disorder NOS
Interventions
Interpersonal and social rhythm therapy
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2016 · Synced Oct 30, 2026, 10:37 PM EDT
Completed No phase listed Observational Results available

Mechanisms of Mindfulness-based Interventions

NCT03571386
View directory record Official record
Conditions
Depression, Anxiety, Stress
Interventions
Mindfulness-based Cognitive Therapy (MBCT), Mindfulness-based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 30, 2026, 10:37 PM EDT
Completed No phase listed Observational

Voice Biomarkers Predictive of Depression and Anxiety

NCT05455905
View directory record Official record
Conditions
Depression, Anxiety, Healthy, Mental Health Wellness 1
Interventions
Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale
Diagnostic Test
Lead sponsor
Kintsugi Mindful Wellness, Inc.
Industry
Eligibility
18 Years and older
Enrollment
19,533 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 30, 2026, 10:37 PM EDT