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ClinicalTrials.gov public records Last synced Oct 30, 2026, 6:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1969–1992 of 5,335 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression Clear all
Completed Not applicable Interventional Results available

Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression

NCT01683019
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
NeoSync EEG Synchronization Therapy, Sham NeoSync EEG Synchronization Therapy
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

NCT01600131
View directory record Official record
Conditions
Depression, Quality of Life, Self Efficacy, Recovery of Function, Stress, Positive Aspects of Caregiving
Interventions
Caregiver problem-solving, Standard Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
3
States / cities
Gainesville, Florida • Miami, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive Disorder

NCT01469377
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Placebo, Cariprazine
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years to 65 Years
Enrollment
819 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
39
States / cities
Garden Grove, California • National City, California • Oceanside, California + 34 more
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD)

NCT01898429
View directory record Official record
Conditions
Treatment Resistant Depression, Depressive Disorder, Treatment-Resistant, Depression, Bipolar
Interventions
SCC DBS
Device
Lead sponsor
Paul Holtzheimer
Other
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Meru Health Program for Cancer Patients With Depression and Anxiety

NCT05588622
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Meru Health Program
Behavioral
Lead sponsor
Meru Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress

NCT04329702
View directory record Official record
Conditions
Cardiorespiratory Failure
Interventions
Coping skills training mobile app with call from CST therapist, Coping skills training mobile app only
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 30, 2026, 6:06 AM EDT
Recruiting No phase listed Observational

fMRI Accelerated TMS Depression

NCT06562153
View directory record Official record
Conditions
Depression
Interventions
Neuroimaging with Magnetic Resonance Imaging (MRI)
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 30, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

Mindfulness-Based fMRI Neurofeedback for Depression

NCT05617495
View directory record Official record
Conditions
Depression in Adolescence, Rumination
Interventions
Mindfulness + fMRI Neurofeedback
Other
Lead sponsor
Columbia University
Other
Eligibility
13 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Completed No phase listed Observational

Biomarker Establishment for Superior Treatment of PTSD

NCT03343028
View directory record Official record
Conditions
PTSD
Interventions
Psychotherapy
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Palo Alto, California • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 30, 2026, 6:06 AM EDT
Completed No phase listed Observational

Mild Depression 2 Week Observational Study

NCT00285831
View directory record Official record
Conditions
Depressive Disorder
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 30, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

NCT07359157
View directory record Official record
Conditions
Serious Mental Illness, Psychotic Disorder, Depression, Bipolar
Interventions
Changing Lives and Changing Outcomes-9
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Completed No phase listed Observational

Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson's Patients

NCT00179101
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
50 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 15, 2006 · Synced Oct 30, 2026, 6:06 AM EDT
Not listed Not applicable Interventional

From Intention to Action:Scoring Your College Goals

NCT05047081
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Scoring Your College Goals Workshop, Placebo
Behavioral · Other
Lead sponsor
The Zucker Hillside Hospital
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet and Telephone Support Intervention for Stroke Caregivers

NCT04348851
View directory record Official record
Conditions
Depression, Quality of Life, Recovery of Function, Self Efficacy, Stress
Interventions
Caregiver problem-solving, Attention Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression

NCT04301895
View directory record Official record
Conditions
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression, Safety Issues
Interventions
Continuous conversational interaction, Remifentanil infusion
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 30, 2026, 6:06 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Neonatal Neurodevelopmental Outcomes

NCT07101757
View directory record Official record
Conditions
Food Insecurity, Depression, Anxiety, Stress
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Treatment for Depressed Primary Care Patients

NCT01014312
View directory record Official record
Conditions
Depression
Interventions
Depression Care Management (DCM), Enhanced Care
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 30, 2026, 6:06 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating an Online Wellness Intervention for Greek Adolescents

NCT04815681
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Happiness
Interventions
Common Elements Toolbox, Active Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 20 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 30, 2026, 6:06 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and Social Behavior Over the Lifespan

NCT00914953
View directory record Official record
Conditions
Social Activity
Interventions
oxytocin (Pitocin)
Drug
Lead sponsor
Claremont Graduate University
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2012 · Synced Oct 30, 2026, 6:06 AM EDT
Recruiting Phase 4 Interventional

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05282277
View directory record Official record
Conditions
Depression, Psychosis, Anhedonia
Interventions
Transdermal Estradiol, Micronized Progesterone, Matching Placebo Patch, Raclopride C11
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
45 Years to 55 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Not listed Not applicable Interventional

Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions

NCT05563857
View directory record Official record
Conditions
Mental Health, Depression, Anxiety
Interventions
VIOME Precision Nutrition Program, VIOME-designed condition-based supplements
Combination Product · Dietary Supplement
Lead sponsor
Viome
Industry
Eligibility
25 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 30, 2026, 6:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health and Health Care Utilization Effects of Medical Debt Forgiveness

NCT04835012
View directory record Official record
Conditions
Health Care Utilization, Depression, Anxiety, Subjective Wellbeing
Interventions
Medical debt forgiveness
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
15,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Active, not recruiting Early Phase 1 Interventional

Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)

NCT04846829
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Placebo, intermittent theta burst stimulation, intravenous citalopram hydrochloride (CIT), continuous theta burst stimulation
Drug · Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 30, 2026, 6:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Unmute's CARE Framework: A Novel Approach to Strengthen the Therapeutic Alliance and Reduce Treatment Disparities

NCT06625502
View directory record Official record
Conditions
Depression Scale Score, Anxiety Symptoms, Functioning, Psychosocial, Working Alliance
Interventions
Culturally-Affirming Racial Equity Framework
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Chelsea, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 30, 2026, 6:06 AM EDT