Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 11, 2026, 10:25 PM EDT

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Showing 1–24 of 242 matching trials from the live ClinicalTrials.gov search.
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Conditions
Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions
Real LED Treatment, Sham LED Treatment
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
38 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Conditions
Depression, Parkinson's Disease (PD)
Interventions
Psilocybin (drug)
Drug
Lead sponsor
Yale University
Other
Eligibility
40 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Treatment Resistant Major Depressive Disorder
Interventions
Activa Tremor Control Sys (DBS Implant), Randomized, staggered withdrawal phase
Device · Other
Lead sponsor
Wayne Goodman MD
Other
Eligibility
21 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Houston, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

The COMParing App Support Strategies Study

NCT07278466
Conditions
Depression, Anxiety
Interventions
Introductory Coaching Session, Introductory Information Session, On-Demand Email Support, Microsupport
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
688 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Depression Disorders
Interventions
Kandoo
Device
Lead sponsor
Child Mind Institute
Other
Eligibility
13 Years to 25 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

NCT06856057
Conditions
Quality of Life, PTSD, Depression Not Otherwise Specified, Child Externalizing Behavior
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Los Angeles, California • Lexington, Kentucky • Ann Arbor, Michigan + 1 more
Active, not recruiting Not applicable Interventional

EPI-MINN: Targeting Cognition and Motivation - National

NCT05877716
Conditions
Psychosis, Psychosis Nos/Other, Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Prodromal Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizophreniform Disorders, Major Depression With Psychotic Features, Unspecified Psychosis, Bipolar Disorder
Interventions
Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 40 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers

Training Resiliency in Youth (TRY) Study

NCT03429465
Conditions
Attention Concentration Difficulty, Depression, Anxiety
Interventions
EVO Cognitive Remediation Game
Other
Lead sponsor
University of Washington
Other
Eligibility
Not listed
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Seattle, Washington
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The University of Oregon ACCESS Project

NCT07264621
Conditions
School Attendance, School Climate, School Engagement, School Exclusion, Externalizing Behavior, Disparities, Teacher-student Relationships, Stress, Emotional Regulation, Depression
Interventions
Inclusive Skill-building Learning Approach (ISLA), Family Check-Up Online (FCU-O), FCU-Online with telehealth coaching
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
11 Years and older
Enrollment
1,440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
13
States / cities
Cottage Grove, Oregon • Eugene, Oregon • Springfield, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

Project SOLVE: Trial of a Brief Digital Problem-solving Intervention

NCT04806321
Conditions
Anxiety, Depression, Stress
Interventions
Project SOLVE, Project SUCCESS
Other
Lead sponsor
Harvard University
Other
Eligibility
10 Years to 14 Years
Enrollment
522 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Substance Use Disorders, HIV, Depression, Anxiety
Interventions
Clinic-based screening and behavioral interventions
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
10,821 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Oakland, California
Conditions
Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)
Interventions
Time Restricted Eating
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Home-based tDCS in Major Depressive Disorder

NCT04799405
Conditions
Major Depressive Disorder
Interventions
tDCS
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
50 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions
AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation
Behavioral · Device
Lead sponsor
Tactical Mind Research Coalition, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Depression, Depression, Anxiety, Depression in Adolescence, Anxiety
Interventions
CBToolkit
Other
Lead sponsor
3-C Institute for Social Development
Industry
Eligibility
13 Years to 17 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Depression, Anxiety
Interventions
COMET-BA (Common Elements Toolbox- Behavioral Activation)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Depression, Anxiety
Interventions
Meru Health Program, Treatment as Usual
Behavioral
Lead sponsor
Meru Health, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Major Depressive Disorder
Interventions
Levomilnacipran, Quetiapine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Alpharetta, Georgia
Conditions
Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
Interventions
Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Palo Alto, California • Syracuse, New York
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers Results available

A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19

NCT04524598
Conditions
Depression
Interventions
Limbix Spark, Psychoeducation
Device · Other
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Depressive Disorder, Anxiety, Adolescent
Interventions
Breathing Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Albert Lea, Minnesota • Eau Claire, Wisconsin
Conditions
Depression, Depressive Disorder, Depressive Symptoms, Depressive Episode, Adolescent Behavior, Adolescent - Emotional Problem, Hematologic Diseases, Oncology, Weight, Body
Interventions
CBT-based mobile intervention for depression, Mobile control with education about depression
Device
Lead sponsor
Limbix Health, Inc.
Industry
Eligibility
13 Years to 22 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Audio-based Mental Health Intervention Study

NCT05555745
Conditions
Depressive Symptoms
Interventions
Audio-based behavioral activation intervention, Audio-based self-monitoring intervention
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania