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ClinicalTrials.gov public records Last synced Oct 4, 2026, 2:01 AM EDT

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Showing 25–48 of 1,034 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Depression and Anxiety Symptom Clear all
Withdrawn Not applicable Interventional

Videoconferencing Acceptance and Commitment Therapy With a Web App Use for Family Caregivers of People With Dementia

NCT05518968
View directory record Official record
Conditions
Depression
Interventions
Acceptance and commitment therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project PRIDE (Promoting Resilience In Discriminatory Environments)

NCT03528135
View directory record Official record
Conditions
Human Immunodeficiency Virus, Sexually Transmitted Infections, Anxiety, Depression, Substance Use Disorders
Interventions
Project PRIDE
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Media Project and Health Study - Spanish Version

NCT04862624
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Catalina Story-Based Web-App, Attention Control Web-App
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 4, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE)

NCT07055906
View directory record Official record
Conditions
Depressive Symptoms, Anxiety Symptoms, Conduct Problems
Interventions
Video-feedback Intervention to Promote Racial-Ethnic Socialization CompEtency (VIP-RACE)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
10 Years to 14 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 4, 2026, 2:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

WILD 5 Wellness: A 30-Day Intervention

NCT03272555
View directory record Official record
Conditions
Wellness, Anxiety, Depression, Cognitive and Executive Dysfunction
Interventions
WILD 5 Wellness Interventions
Other
Lead sponsor
Beloit College
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Beloit, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

IntelliCare: Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM)

NCT02176226
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety Disorders
Interventions
IntelliCare
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
19 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Medical Marijuana on Neurocognition and Escalation of Use

NCT03224468
View directory record Official record
Conditions
Pain, Insomnia, Depression, Anxiety
Interventions
Medical Marijuana
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2023 · Synced Oct 4, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional

Multidimensional Sleep Health Intervention to Optimize Concussion Recovery

NCT07082218
View directory record Official record
Conditions
Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury, Treatment, Sleep Health, Depression, Anxiety
Interventions
Sleep Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 19 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Connection to Care: Pilot Study of a Mobile Health Tool for Patients With Depression and Anxiety

NCT02497755
View directory record Official record
Conditions
Anxiety, Depression
Interventions
App for smartphone, smartphone
Behavioral · Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 4, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Prison Inmates' Attitudes and Internal Emotional States

NCT04374357
View directory record Official record
Conditions
Forgiveness
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Male only
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Portage, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 4, 2026, 2:01 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

New Mothers Alpha-Stim

NCT04770181
View directory record Official record
Conditions
Anxiety, Depression, Insomnia, Sleep Quality
Interventions
Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator)
Device
Lead sponsor
Christina Murphey, RN, PhD
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 4, 2026, 2:01 AM EDT
Terminated Phase 4 Interventional Results available

Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines

NCT01244711
View directory record Official record
Conditions
Major Depression, Generalized Anxiety Disorder
Interventions
quetiapine
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Oct 4, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms of Anxiety and Depression Study

NCT03135756
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Not listed
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 55 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Los Altos, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures

NCT05575128
View directory record Official record
Conditions
Cardiac Surgery, Older Adults, Depression, Anxiety
Interventions
Behavioral activation, Medication optimzation, Care as usual
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 4, 2026, 2:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility of Collateral Information Review and Its Impact on Clinical Decision-Making

NCT04635748
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders
Interventions
Not listed
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 4, 2026, 2:01 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Investigation of Neuro-hormonal Mechanisms of Hunger, Fullness and Obesity.

NCT01008371
View directory record Official record
Conditions
Obesity, Gastric Emptying, Anxiety, Depression, Panic Disorder
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2013 · Synced Oct 4, 2026, 2:01 AM EDT
Completed No phase listed Observational

The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels

NCT01385709
View directory record Official record
Conditions
Bipolar Affective Disorders, Cyclothymic Disorder, Schizoaffective Disorder, Major Depressive Disorder, Dysthymic Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 4, 2026, 2:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strengthening Health and Insight in New Educators

NCT06745934
View directory record Official record
Conditions
Anxiety Symptoms, Depressive Symptoms
Interventions
Healthy Minds Program
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use

NCT04595084
View directory record Official record
Conditions
Depression, Anxiety, Substance Use, Stress, Psychological, Stress, Emotional, Alcohol Use, Unspecified, Drug Use, Covid19
Interventions
Mindfulness Based Cognitive Therapy for Resilience During COVID-19 plus CHAMindWell, Internet Cognitive Behavioral Therapy plus CHAMindWell, CHAMindWell
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional

Affect Treatment for Depression and Anxiety

NCT05203861
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Positive Affect Treatment, Negative Affect Treatment
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional

PRISM for Depression and Anxiety in Young Adults With Cancer

NCT06502483
View directory record Official record
Conditions
Cancer Diagnosis, Non-Metastatic Neoplasm, Anxiety, Anxiety Disorders, Depression, Depressive Disorder, Depression, Anxiety, Desmoid
Interventions
Promoting Resilience in Stress Management Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 4, 2026, 2:01 AM EDT
Terminated Not applicable Interventional Results available

Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment

NCT04587661
View directory record Official record
Conditions
Sickle Cell Disease, Depression, Anxiety
Interventions
off-the-shelf digital CBT, adapted digital CBT
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 35 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 4, 2026, 2:01 AM EDT
Completed Not applicable Interventional Results available

Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers

NCT01983254
View directory record Official record
Conditions
Intensive Care Unit Survivors, Informal Caregivers (Family and Friends)
Interventions
coping skills training, education program
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 4, 2026, 2:01 AM EDT
Completed No phase listed Observational

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 4, 2026, 2:01 AM EDT