- Conditions
- Aging, Depression, Cognitive Symptoms
- Interventions
- Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation)
- Behavioral · Device
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
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Showing 1–24
of 98
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Depression
- Interventions
- paroxetine, One night of Total Sleep Deprivation
- Drug · Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 158 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2003
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Depression in Old Age, Depression
- Interventions
- Experimental: Computerized Cognitive Training, Experimental: Open-label antidepressant treatment, Active Comparator: Solitaire Training, Placebo Comparator: Placebo-controlled antidepressant treatment
- Other · Drug
- Lead sponsor
- Queens College, The City University of New York
- Other
- Eligibility
- 50 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke, Cancer, Bleeding, Depression, Frailty
- Interventions
- Not listed
- Lead sponsor
- Anne Murray
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 19,114 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2026
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Washington D.C., District of Columbia • Atlanta, Georgia + 18 more
- Conditions
- Depressive Disorder, Major
- Interventions
- Aticaprant
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 871 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 87
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 70 more
- Conditions
- Depression
- Interventions
- lithium and Venlafaxine, ECT
- Drug · Procedure
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 247 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 10
- States / cities
- Augusta, Georgia • Rochester, Minnesota • Hoboken, New Jersey + 6 more
- Conditions
- Depression in Old Age
- Interventions
- Endotoxin, Placebo
- Biological
- Lead sponsor
- Michael Irwin, MD
- Other
- Eligibility
- 60 Years to 80 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Bipolar Depression
- Interventions
- Lamotrigine
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Major Depressive Disorder
- Interventions
- Tai-Chi-Chih (TCC), Health Education and Wellness Classes (HEW)
- Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Depression
- Interventions
- Citalopram, Methylphenidate (MPH), Placebo
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Lymphoma Cancer, Gynecological Cancers
- Interventions
- group intervention and questionnaires, individual phone intervention and questionnaires, expressive writing (arm will not be include in the randomization)
- Behavioral
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Eligibility
- 70 Years and older
- Enrollment
- 107 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2025
- U.S. locations
- 2
- States / cities
- New York, New York • Philadelphia, Pennsylvania
- Conditions
- Dementia
- Interventions
- New York University Caregiver Intervention (NYUCI), Community Health Worker (CHW) Case Management
- Behavioral · Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 139 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Depressive Disorder, Major, Major Depressive Disorder (MDD)
- Interventions
- Paroxetine CR
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 60 Years and older
- Enrollment
- 560 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 46
- States / cities
- Little Rock, Arkansas • Anaheim, California • Beverly Hills, California + 40 more
- Conditions
- Subjective Cognitive Decline, Depression in Old Age
- Interventions
- PeersCOG
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Depressive Disorder, Major
- Interventions
- Seltorexant, Matching placebo to Seltorexant, Quetiapine XR, Matching placebo to Quetiapine XR
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 757 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 75
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Culver City, California + 62 more
- Conditions
- Bipolar Depression Depressed Phase
- Interventions
- Active Low Field Magnetic Stimulation, Sham Low Field Magnetic Stimulation
- Device
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Depressive Disorder, Major
- Interventions
- Seltorexant, Placebo
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 16
- States / cities
- Bellflower, California • Oceanside, California • Walnut Creek, California + 13 more
- Conditions
- Bipolar Depression
- Interventions
- CoEnzyme Q10
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 55 Years to 89 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Depression, Cognition
- Interventions
- Duloxetine, Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 311 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2004
- U.S. locations
- 1
- States / cities
- Middleton, Wisconsin
- Conditions
- Major Depressive Disorder
- Interventions
- Placebo, Brexpiprazole 1 mg, Brexpiprazole 3 mg
- Drug
- Lead sponsor
- H. Lundbeck A/S
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 129 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 2
- States / cities
- National City, California • Orlando, Florida
- Conditions
- Depression in Old Age
- Interventions
- Engage-A, Training and utilizing Engage-A therapy
- Behavioral · Other
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- White Plains, New York
- Conditions
- Depression in Old Age
- Interventions
- Peers plus
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Bipolar Depression
- Interventions
- Coenzyme Q10
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 55 Years to 89 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Depression
- Interventions
- Problem Solving Therapy, Dietary Education
- Behavioral
- Lead sponsor
- University of Maryland, College Park
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 306 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2013
- U.S. locations
- 2
- States / cities
- Pittsburgh, Pennsylvania