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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Diplegia, Spastic Clear all
Completed No phase listed Observational

Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers

NCT01971957
View directory record Official record
Conditions
Sjogren-Larsson Syndrome (SLS)
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
2
States / cities
Omaha, Nebraska • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jul 22, 2026, 5:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Eye-Hand Coordination in Children With Spastic Diplegia

NCT00024791
View directory record Official record
Conditions
Diplegia, Spastic
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Addictive Potential of LCCs in Dual Users

NCT03496077
View directory record Official record
Conditions
Tobacco Use Disorder, Dual Tobacco Use, Tobacco Dependence, Smoking, Smoking, Cigar, Smoking, Cigarette, Smoking, Tobacco
Interventions
Flavored and unflavored little cigars/cigarillos (LCCs)
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 34 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Prevention Program for Obese Latino Youth

NCT02039141
View directory record Official record
Conditions
Obesity, Insulin Resistance, Diabetes
Interventions
Every Little Step Counts Intervention
Other
Lead sponsor
Arizona State University
Other
Eligibility
14 Years to 16 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Precision Gait Retraining for Children With Cerebral Palsy

NCT04717323
View directory record Official record
Conditions
Cerebral Palsy, Gait Disorders, Neurologic
Interventions
mPAD (or TPAD) Pelvic Assist Device, No Intervention
Device
Lead sponsor
Altec Inc.
Industry
Eligibility
6 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Natick, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Jul 22, 2026, 5:13 AM EDT
Completed No phase listed Observational Results available

The Role of Cerebellar Hyperactivity in Parkinson's Disease

NCT02349789
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Cerebral Palsy: Short-burst Interval Training

NCT03373890
View directory record Official record
Conditions
Cerebral Palsy Spastic Diplegia
Interventions
Short Burst Interval Locomotor Treadmill Training (SBLTT)
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
5 Years to 12 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Little Cigar and Cigarillo Warnings for Youth

NCT06413797
View directory record Official record
Conditions
Little Cigars and Cigarillos (LCC) Use
Interventions
FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
15 Years to 20 Years
Enrollment
928 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine Metabolism and Little Cigars

NCT01898559
View directory record Official record
Conditions
Smoking
Interventions
Switch to smoking only little cigars
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 22, 2026, 5:13 AM EDT
Not listed Phase 1 Interventional

Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy

NCT00356343
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
NMES Strength Training, Volitional Strength Training
Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
7 Years to 12 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 10, 2011 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional

FES Assisted Cycling in Children With CP

NCT04688424
View directory record Official record
Conditions
Cerebral Palsy Spastic Diplegia
Interventions
FES, Cycling
Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
10 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Jul 22, 2026, 5:13 AM EDT
Recruiting No phase listed Observational

Growing Little PEAPODS Study

NCT06226051
View directory record Official record
Conditions
Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction, Small for Gestational Age at Delivery
Interventions
PEAPOD Infant Body Composition measuring device
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
22 Weeks to 32 Weeks
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Jul 22, 2026, 5:13 AM EDT
Terminated Not applicable Interventional

Trigger Finger Preference Elicitation Tool

NCT03909490
View directory record Official record
Conditions
Trigger Finger, Trigger Thumb, Trigger Digit, Trigger Finger Disorder, Trigger Thumb, Left Thumb, Trigger Thumb, Right Thumb, Trigger Finger, Ring Finger, Trigger Finger, Index Finger, Trigger Finger, Middle Finger, Trigger Finger, Little Finger, Trigger Thumb, Unspecified Thumb, Trigger Finger, Unspecified Finger
Interventions
Preference elicitation tool, handout
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Study of a Stationary Cycling Intervention for Children With Spastic Diplegic Cerebral Palsy

NCT00401154
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
Stationary Cycling
Other
Lead sponsor
University of Southern California
Other
Eligibility
7 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Phase 3 Interventional

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

NCT00002334
View directory record Official record
Conditions
HIV Infections
Interventions
Saquinavir, Zidovudine, Zalcitabine
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
25
States / cities
Phoenix, Arizona • Sacramento, California • San Francisco, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 22, 2026, 5:13 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Healthy Little Eyes

NCT05971446
View directory record Official record
Conditions
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
Interventions
Visual Evoked Potential (VEP), Electroretinogram (ERG)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 36 Months
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jul 22, 2026, 5:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Bottle Optimization Testing Tiny Little Eaters Study

NCT07665983
View directory record Official record
Conditions
Childhood Obesity
Interventions
Feeding
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
4 Months and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs

NCT05849051
View directory record Official record
Conditions
Tobacco Use
Interventions
Newly developed warnings with images at 30% size, FDA proposed text-only warnings at 30% size
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
1,029 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 22, 2026, 5:13 AM EDT
Recruiting Not applicable Interventional

Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

NCT02535936
View directory record Official record
Conditions
Spastic Diplegia
Interventions
3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention

NCT02829528
View directory record Official record
Conditions
ADHD
Interventions
Little Flower Yoga For Kids
Behavioral
Lead sponsor
New York University
Other
Eligibility
5 Years to 7 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Jul 22, 2026, 5:13 AM EDT
Recruiting Not applicable Interventional

Little Cigar Oxidants

NCT06310187
View directory record Official record
Conditions
Tobacco Use, Oxidative Stress
Interventions
High Oxidant Little Cigar, Low Oxidant Little Cigar, Usual Cigarette
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 22, 2026, 5:13 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Little Lungs Study

NCT06855043
View directory record Official record
Conditions
Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Interventions
Calfactant, Budesonide
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
7 Days to 14 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Phase 2 Interventional

Does Reducing Spasticity Permit an Increase in Strength?

NCT00255073
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
baclofen
Drug
Lead sponsor
University of Southern California
Other
Eligibility
5 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Jul 22, 2026, 5:13 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dose Exploration Intramuscular/Intravenous Prophylaxis Pharmacokinetic Exposure Response Study

NCT05872958
View directory record Official record
Conditions
COVID-19
Interventions
AZD3152, Placebo
Drug · Other
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 55 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
4
States / cities
Anniston, Alabama • Cullman, Alabama • Scottsdale, Arizona + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Jul 22, 2026, 5:13 AM EDT