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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:46 AM EDT

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Showing 457–480 of 28,982 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Disease;Neurological Clear all
Recruiting Phase 2 Interventional

IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage

NCT07054801
View directory record Official record
Conditions
Headaches Associated With Subarachnoid Hemorrhage (SAH)
Interventions
Lidocaine hydrochloride, Methylprednisolone sodium succinate
Drug
Lead sponsor
Daniel Raper, MBBS
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

NCT01031901
View directory record Official record
Conditions
Tuberous Sclerosis, Neurofibromatoses, Angiofibroma, Neurofibroma
Interventions
Skincerity, Skincerity plus sirolimus/rapamycin, Skinercity plus sirolimus/rapamycin
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
13 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Oct 20, 2026, 8:46 AM EDT
Terminated Phase 2 Interventional Results available

PR3-AAV Resilient Remission or PRRR

NCT05376319
View directory record Official record
Conditions
Granulomatosis With Polyangiitis, Microscopic Polyangiitis, ANCA Associated Vasculitis
Interventions
Obinutuzumab, Rituximab
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, Minnesota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Phase 2 Interventional

A Study With RO4917523 in Patients With Fragile X Syndrome

NCT01015430
View directory record Official record
Conditions
Fragile X Syndrome
Interventions
Placebo (for RO4917523 ascending doses), Placebo (for RO4917523 fixed dose), RO4917523
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
5
States / cities
Sacramento, California • Decatur, Georgia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 20, 2026, 8:46 AM EDT
Recruiting Not applicable Interventional

Fall Risk Intervention for Stroke

NCT07349030
View directory record Official record
Conditions
Stroke
Interventions
Fall Prevention Intervention, Active Control
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
45 Years to 85 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Early Phase 1 Interventional

Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People

NCT06496230
View directory record Official record
Conditions
Opioid Use Disorder, Pregnancy Related
Interventions
Empowering Pregnant Women and People Receiving Medications for Opioid Use Disorder
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional

Evaluation of a Telehealth Lifestyle Management Program to Improve Healthy Behaviors Post Head Injury

NCT02223728
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Lifestyle, Health Education
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 20, 2026, 8:46 AM EDT
Terminated Phase 1 Interventional

Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors

NCT02134067
View directory record Official record
Conditions
Advanced Solid Tumors
Interventions
TAS-119, Paclitaxel
Drug
Lead sponsor
Taiho Oncology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
4
States / cities
Aurora, Colorado • St Louis, Missouri • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature

NCT03580200
View directory record Official record
Conditions
Trigger Point, Muscle Weakness
Interventions
Trigger Point Dry Needling
Other
Lead sponsor
Emily Slaven, PT, PhD
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional

Lumbar Plexus Block Versus Quadratus Lumborum Block for Primary Anterior Total Hip Arthroplasty

NCT03409900
View directory record Official record
Conditions
Osteoarthritis, Total Hip Arthroplasty
Interventions
LPB, QLB
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 95 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional

Coaching for Cognition in Alzheimer's (COCOA)

NCT03424200
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Impairment
Interventions
Routine care, Coaching plus routine care
Behavioral · Other
Lead sponsor
Hoag Memorial Hospital Presbyterian
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Oct 20, 2026, 8:46 AM EDT
Active, not recruiting No phase listed Observational

Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients

NCT04098211
View directory record Official record
Conditions
Neuronal Ceroid-Lipofuscinoses, Neuronal Ceroid Lipofuscinosis CLN2, Spinocerebellar Ataxia, Autosomal Recessive 7
Interventions
Not listed
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
4 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Not listed No phase listed Observational

Phase I/II Study of Neuroendocrine Dysfunction in Patients With Closed Head Injuries

NCT00006271
View directory record Official record
Conditions
Brain Injury
Interventions
Not listed
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1997
U.S. locations
2
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 20, 2026, 8:46 AM EDT
Terminated Not applicable Interventional

Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy

NCT01850771
View directory record Official record
Conditions
Radiculopathy, Herniated Disc, Disc Degeneration
Interventions
Regenexx PL-Disc, Steroid Epidural
Procedure
Lead sponsor
Regenexx, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Broomfield, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 20, 2026, 8:46 AM EDT
Recruiting Phase 1Phase 2 Interventional

Open-label Study of SKY-GJB2 in Pediatric Subjects With GJB2-mediated Hearing Loss

NCT07627971
View directory record Official record
Conditions
GJB2-mediated Hearing Loss, GJB2 Gene Mutation, DFNB1A
Interventions
SKY-GJB2
Combination Product
Lead sponsor
Skylark Bio Inc.
Industry
Eligibility
9 Months to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Bethesda, Maryland • Boston, Massachusetts • Oklahoma City, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Completed No phase listed Observational

Associations of Socioeconomic Adversity and Sleep With Allostatic Load Among Toddlers

NCT03419871
View directory record Official record
Conditions
Sleep Disorder
Interventions
Monitoring Sleep, stress biomarkers
Other
Lead sponsor
Yale University
Other
Eligibility
12 Months to 15 Months
Enrollment
100 participants
Timeline
2015 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 20, 2026, 8:46 AM EDT
Recruiting Not applicable Interventional

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

NCT05663034
View directory record Official record
Conditions
Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress, Sleep, Memory Impairment, Cognitive Behavioral Therapy, Concussion, Brain, Head Injury, Brain Injury Traumatic Mild
Interventions
Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Eglin Air Force Base, Florida • Bethesda, Maryland • Fort Bragg, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Recruiting No phase listed Observational

Trial-Ready Cohort-Down Syndrome (TRC-DS)

NCT04165109
View directory record Official record
Conditions
Down Syndrome, Alzheimer Disease, Dementia
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
25 Years to 55 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
18
States / cities
Phoenix, Arizona • Orange, California • Aurora, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Recruiting Not applicable Interventional

ACT for Dementia Caregivers: Evaluating Psychological Flexibility as the Mechanism to Improve Psychological Distress

NCT07845032
View directory record Official record
Conditions
Dementia Caregivers
Interventions
ACT for Caregivers
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 20, 2026, 8:46 AM EDT
Withdrawn Phase 1 Interventional

Study of Admission Versus Discharge After Transient Ischemic Attack (TIA)

NCT00304798
View directory record Official record
Conditions
Transient Ischemic Attack (TIA), Stroke
Interventions
Hospital admission
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Oct 20, 2026, 8:46 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia

NCT00895063
View directory record Official record
Conditions
Spasmodic Dysphonia, Dystonia
Interventions
Vocal Exercise
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional

Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis

NCT01647321
View directory record Official record
Conditions
Secondary Progressive Multiple Sclerosis
Interventions
Active cycling, Passive cycling
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 68 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 20, 2026, 8:46 AM EDT
Terminated Not applicable Interventional

Acupressure for Pain and Opioid Use Among Breast Cancer Patients

NCT03655600
View directory record Official record
Conditions
Breast Cancer, Fatigue, Chronic Pain
Interventions
Self-administered acupressure
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 20, 2026, 8:46 AM EDT
Completed Not applicable Interventional

Chronic Insomnia and CSF Markers of Dementia - Effects of Treatment

NCT04073992
View directory record Official record
Conditions
Insomnia Chronic
Interventions
cognitive behavioral treatment of insomnia
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 20, 2026, 8:46 AM EDT