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Showing 1–24 of 234 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Distress, Emotional Clear all
Recruiting Phase 2 Interventional Accepts healthy volunteers

Meditation to Reduce Firefighter Distress

NCT06518616
View directory record Official record
Conditions
Psychological Distress
Interventions
10-day meditation intervention, 10-day health education intervention
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 21, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

ASCENT Intervention for Brain Tumor Patients

NCT06099743
View directory record Official record
Conditions
Malignant Brain Tumor, Glioma, Coping Skills, Distress, Emotional
Interventions
Psychosocial intervention, Usual supportive care
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jul 21, 2026, 5:23 PM EDT
Active, not recruiting Not applicable Interventional

Improving Care, Accelerating Recovery and Education

NCT06233747
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examine the Psychosocial Impacts of COVID-19 Pandemic.

NCT05052333
View directory record Official record
Conditions
Psychosocial Impacts, COVID-19 Pandemic
Interventions
Not listed
Lead sponsor
University of Otago
Other
Eligibility
18 Years and older
Enrollment
2,574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional

REstoring Mental Health Through COmmUnity-based Psychological Services in New York City

NCT04913766
View directory record Official record
Conditions
Depression, Anxiety, Psychological Distress, PTSD
Interventions
Problem Management Plus, Services as Usual
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
1,206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SoCal Savvy: Testing Savvy Caregiver in a Racially and Ethnically Diverse Sample in Southern California

NCT04421729
View directory record Official record
Conditions
Caregiver Burnout, Psychological Distress
Interventions
Group sessions over 3 weeks, Group sessions over 6 weeks
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Jul 21, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)

NCT07502352
View directory record Official record
Conditions
Breast Cancer
Interventions
Remotely Delivered Cognitive Behavioral Stress Management Intervention (R-CBSM), Standard of Care Survivorship Care Planning
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
50 Years and older · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Intuitive Eating for Disordered Eating

NCT05031611
View directory record Official record
Conditions
Eating Disorder Symptom, Eating Behavior, Body Image, Psychological Distress
Interventions
Intuitive Eating Treatment
Behavioral
Lead sponsor
Yeshiva University
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Psychological Intervention For Brain Tumor Caregivers

NCT04109209
View directory record Official record
Conditions
Malignant Glioma, Anxiety, Caregiver Burden, Malignant Brain Tumor
Interventions
Psychosocial Intervention Group, Usual Care Group
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Three-Principles Approach for Incarcerated Adults

NCT04747704
View directory record Official record
Conditions
Psychological Distress, Recidivism
Interventions
Three Principles Counseling
Behavioral
Lead sponsor
Pacific University
Other
Eligibility
21 Years to 65 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Hillsboro, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Well-being Promotion and Sleep Hygiene Education to Improve Sleep Quality

NCT04316663
View directory record Official record
Conditions
Poor Quality Sleep
Interventions
Well-Being Intervention, Sleep Hygiene
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of DBT/Parent Training Group Intervention

NCT04740138
View directory record Official record
Conditions
Parenting, Emotional Distress
Interventions
Dialectical Behavioral Therapy Skills + Parent Training
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 21, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Supporting Evidence-based Responses to Emotional Needs in Emphysema

NCT06600126
View directory record Official record
Conditions
COPD
Interventions
Coping Skills Training, COPD Education
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Detroit, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration

NCT04785677
View directory record Official record
Conditions
Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Depressive Symptoms, Anxiety, Substance Use, Aggression, Coping Skills, Impulsive Behavior, Housing Problems, Recidivism, Stress, Occupational Stress, Psychological Distress
Interventions
Resiliency in Stressful Experiences (RISE) Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
403 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Enhancing Emotion Regulation During Driving in OEF/OIF Veterans

NCT01336764
View directory record Official record
Conditions
Driving Distress Secondary to Trauma During Deployment
Interventions
Cognitive reappraisal and breathing retraining, Control
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With Cancer

NCT03778658
View directory record Official record
Conditions
Adolescent, Young Adult, Cancer, Physical Activity, Psychological Distress, Social Isolation
Interventions
Physical Activity Intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
15 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Jul 21, 2026, 5:23 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Progesterone in Gender Affirming Hormone Therapy Study

NCT06807580
View directory record Official record
Conditions
Transgender Women
Interventions
Placebo, Progesterone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Family Caregivers of People With Dementia

NCT04458870
View directory record Official record
Conditions
Psychological Distress
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Jul 21, 2026, 5:23 PM EDT
Completed No phase listed Observational

Relationship Between Personality and Coping Styles in Bone Marrow Transplant Candidates

NCT00048256
View directory record Official record
Conditions
Adaptation, Psychological, Bone Marrow Transplantation
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Latinos Understanding the Need for Adherence in Diabetes

NCT03983499
View directory record Official record
Conditions
Type 2 Diabetes, Glycemic Control, Cardiovascular Risk Factors, Psychological Distress
Interventions
Special Intervention
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Jul 21, 2026, 5:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Psychological Distress and Outcomes in Hip Preservation Patients

NCT01550263
View directory record Official record
Conditions
Psychological Distress
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Jul 21, 2026, 5:23 PM EDT
Not yet recruiting Not applicable Interventional

Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress

NCT07634419
View directory record Official record
Conditions
Critical Illness, Heart Failure, Sepsis, Ards, Pneumonia, Trauma Injury
Interventions
Lift mobile mindfulness, Enlighten Recovery education program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
3
States / cities
Los Angeles, California • Durham, North Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 21, 2026, 5:23 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Project VALOR: Veteran Stress and Wellbeing

NCT06095817
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet Delivered Brief Intervention (IDBI)
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jul 21, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Messy Memories: Mobile Application Therapy Following Critical Illness

NCT05849454
View directory record Official record
Conditions
Critical Illness, Psychological Distress, Health Behavior
Interventions
Messy Memories Intervention
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 21, 2026, 5:23 PM EDT