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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:42 AM EDT

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Showing 361–384 of 1,122 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Drug Use Disorders Clear all
Completed Not applicable Interventional Results available

A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder

NCT03535129
View directory record Official record
Conditions
Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
Interventions
Real time fMRI neurofeedback
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans

NCT06766331
View directory record Official record
Conditions
Opioid Use Disorder, HIV, Hepatitis C Virus, Gonorrhea, Chlamydia, Syphilis, Sexually Transmitted Infection, Integrated Care, Medications for Opioid Use Disorder
Interventions
Integrated care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2029
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students

NCT06115746
View directory record Official record
Conditions
Substance Use, Harm Reduction, Adolescent Behavior
Interventions
iDECIDE
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
9 Years to 22 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)

NCT03575403
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol, Placebos, Duloxetine (60 MG), Methylphenidate, Duloxetine (30 MG)
Drug
Lead sponsor
Craig Rush
Other
Eligibility
21 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)

NCT07480109
View directory record Official record
Conditions
Obesity, Women (Between 30 to 60 Years Old)
Interventions
Protein Rich Foods
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Not applicable Interventional

Cardiac Surgery Peer Recovery Support Program

NCT03590106
View directory record Official record
Conditions
IV Drug Usage, Infective Endocarditis, Substance Use Disorders
Interventions
Peer Recovery Support Program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Not applicable Interventional Results available

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase

NCT04248933
View directory record Official record
Conditions
Substance Use, Substance Use Disorders, Opioid-use Disorder, Peer Delivered, Medication for Opioid Use Disorder (MOUD), Methadone Treatment, Retention in Care, Behavioral Activation
Interventions
Peer-Delivered Behavioral Activation (Peer Activate)
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Baltimore, Maryland • College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 2 Interventional

Indirect Assessment and Intervention for Perinatal Drug Use

NCT01650675
View directory record Official record
Conditions
Drug Abuse
Interventions
WIDUS computer-delivered, indirect brief intervention, Nutrition time control/placebo intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 4 Interventional Results available

Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder

NCT04170738
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Substance Abuse
Interventions
Adderall
Drug
Lead sponsor
Jeffrey Newcorn
Other
Eligibility
7 Years to 12 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Not applicable Interventional

Improving Delivery of Mental Health Services for Patients With Drug Use and Other Behavioral and Emotional Problems

NCT00787735
View directory record Official record
Conditions
Study Focusing on Integrated Versus Non-integrated Psychiatric Care in, Opioid-dependent and Methadone Treated Patients With Other Psychiatric, Diagnoses
Interventions
Counseling compliance
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 4 Interventional Results available

Drug and Talk Therapy for Fibromyalgia

NCT01038323
View directory record Official record
Conditions
Fibromyalgia
Interventions
CBT and milnacipran, CBT with a placebo, Educational with milnacipran
Other · Behavioral · Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 4 Interventional

Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine Treatment

NCT07336420
View directory record Official record
Conditions
Migraine, Acute Treatment of Migraine
Interventions
Nerivio REN device
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years and older
Enrollment
466 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Developing a Novel Human Laboratory Paradigm for AUD Medication Screening

NCT06489782
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Model 1, Model 2
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Not applicable Interventional Results available

Switching to Potential Reduced Exposure Products in Adult Smokers

NCT04250727
View directory record Official record
Conditions
Tobacco Use Disorder, Oral Nicotine Pouch Use, Smoking Behaviors, Harm Reduction, Toxic Effect of Tobacco and Nicotine, Carcinogenesis
Interventions
ZYN
Device
Lead sponsor
Yale University
Other
Eligibility
21 Years to 77 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 22, 2026, 2:42 AM EDT
Completed No phase listed Observational

Technology for MAT in Primary Care - Phase 1

NCT05006846
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Opioid Addiction Recovery Support Software Platform
Other
Lead sponsor
Q2i, LLC
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 22, 2026, 2:42 AM EDT
Completed No phase listed Observational

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study

NCT03911466
View directory record Official record
Conditions
Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome, Drug Abuse in Pregnancy
Interventions
Buprenorphine Injection, Buprenorphine Sublingual Product
Drug
Lead sponsor
T. John Winhusen, PhD
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
12
States / cities
Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction Champions

NCT06823453
View directory record Official record
Conditions
Opioid Overdose Prevention, People Who Use Opioids/People With Opioid Use Disorder (OUD), Reduction of Substance Use-related Stigma, Non-substance-using People With a Friend or Family Member Who Uses Opioids, Peer Harm Reduction Support Champions
Interventions
Peer Harm Reduction Support Champion Intervention
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Recruiting Phase 3 Interventional

Emergency Department-Initiated Medications for Alcohol Use Disorder

NCT05827159
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview, Gabapentin Pill
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 1 Interventional Results available

Developing a Smoking Cessation Intervention for Methadone Maintained Smokers

NCT01393392
View directory record Official record
Conditions
Nicotine Dependence, Opiate Dependence
Interventions
Intensive, tailored intervention, NJ Quitline Referral
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 22, 2026, 2:42 AM EDT
Active, not recruiting Not applicable Interventional

The Ganchero Intervention for Migrant People Who Inject Drugs From Puerto Rico in New York City

NCT06316739
View directory record Official record
Conditions
HIV Infections, HCV, Overdose
Interventions
Ganchero intervention
Behavioral
Lead sponsor
North Jersey AIDS Alliance dba North Jersey Community Research Initiative (NJCRI)
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 4 Interventional

A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients With Recurrent Thrush

NCT00000951
View directory record Official record
Conditions
Candidiasis, Oral, HIV Infections
Interventions
Fluconazole
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
948 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
53
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 28 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 22, 2026, 2:42 AM EDT
Withdrawn Not applicable Interventional

Suboxone Dispenser for OUD

NCT05790551
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Withdrawal
Interventions
Addinex
Device
Lead sponsor
Addinex Technologies, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Greenwich, Connecticut
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Not applicable Interventional

Pharmacist Use of ECG to Inform Drug Therapy Decisions for Patients Receiving QT Prolonging Medications

NCT04000542
View directory record Official record
Conditions
Torsades de Pointe Caused by Drug (Disorder), Torsades de Pointes, Qt Interval, Variation in
Interventions
Pharmacist Intervention
Other
Lead sponsor
Northeast Iowa Medical Education Foundation
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Waterloo, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 22, 2026, 2:42 AM EDT
Completed Phase 2 Interventional Results available

Ibudilast for the Treatment of Alcohol Use Disorder

NCT03594435
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Ibudilast, Placebo oral capsule
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 22, 2026, 2:42 AM EDT