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Showing 553–576 of 1,123 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

NAC for Treating Comorbid PTSD and SUD

NCT02911285
Conditions
Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
Interventions
N-acetylcysteine, Placebo, Cognitive behavioral therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)

NCT02290938
Conditions
Alcohol Use, Marijuana Use
Interventions
MICUNAY, Community Wellness Gathering
Behavioral · Other
Lead sponsor
RAND
Other
Eligibility
14 Years to 18 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Oakland, California
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Integration of (iSBIRT) for Teen Drug Use Into a Pediatric Network

NCT01454206
Conditions
Substance Use
Interventions
iSBIRT
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

Screening for Youth Alcohol and Drug Use: A Study of Primary Care Providers

NCT02408952
Conditions
Substance Related Disorders
Interventions
Primary Care Physician, Behavioral Medicine Specialist
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 80 Years
Enrollment
9,084 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2025
U.S. locations
1
States / cities
Oakland, California
Conditions
Obesity
Interventions
IHBG-10, Placebo
Dietary Supplement
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Conditions
Cocaine Use Disorders
Interventions
Bupropion
Drug
Lead sponsor
Craig Rush
Other
Eligibility
18 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
HCV Negative Status, HCV Risk Behavior
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Dermatologic Disorders
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Opioid-use Disorder
Interventions
Integration of telemedicine for MOUD in primary care
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
36,762 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
7
States / cities
Cottonwood, Idaho • Grangeville, Idaho • Belfast, Maine + 4 more
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Brief Intervention in Primary Care for Problem Drug Use and Abuse

NCT00877331
Conditions
Substance-Related Disorders
Interventions
Brief intervention using motivational interviewing
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
868 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Pain
Interventions
Morphine Sulfate Immediate Release, Oxycodone/Acetaminophen, Hydrocodone/Acetaminophen
Drug
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Opioid Use Disorder
Interventions
Peer recovery support to enhance patient engagement in medication for opioid use disorder treatment
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Danville, Pennsylvania
Conditions
Candidiasis, Oral, HIV Infections
Interventions
Fluconazole
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
948 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
53
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 28 more
Conditions
HIV Infections, Leukoencephalopathy, Progressive Multifocal
Interventions
Cidofovir, Probenecid
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2001
U.S. locations
19
States / cities
Birmingham, Alabama • San Francisco, California • Denver, Colorado + 10 more
Completed Early Phase 1 Interventional Accepts healthy volunteers

Behavioral Effects of Drugs: Inpatient (35)

NCT03519022
Conditions
Cocaine Use Disorder
Interventions
Cocaine, Placebo oral capsule, Methylphenidate
Drug
Lead sponsor
Craig Rush
Other
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Neoplasm Cervix
Interventions
Curcumin C3 Complex, Placebo
Drug
Lead sponsor
Lisa Flowers
Other
Eligibility
21 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Results available

The Health Check-Up for Expectant Moms

NCT02120716
Conditions
HIV
Interventions
Health Check-Up for Expectant Moms
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
Dutasteride, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Opioid Use Disorder
Interventions
buprenorphine/naloxone, Pharmacist-administered buprenorphine/naloxone maintenance care
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
6
States / cities
Durham, North Carolina • Raleigh, North Carolina
Recruiting Not applicable Interventional

Harm Reduction Services

NCT05776316
Conditions
Drug Use, Substance Abuse, Mental Illness
Interventions
Integrated Harm Reduction Intervention (IHRI)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
New Haven, Connecticut • New York, New York • Orangeburg, New York
Completed Not applicable Interventional Accepts healthy volunteers

Project UNITY - HIV Risk Reduction and Vaccine Education Interventions

NCT00150098
Conditions
HIV Infections, Hepatitis B
Interventions
Enhanced HIV risk reduction and HIV vaccine education
Behavioral
Lead sponsor
New York Blood Center
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Conditions
Familial Hypercholesterolemia, Adherence, Medication
Interventions
Monetary incentives
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Fecal Incontinence
Interventions
magnetic anal sphincter augmentation for fecal incontinence
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota