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Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.
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Not listed Not applicable Interventional

Assessment of the Effects on the Skin Microbiome of Amending an Over-the-counter Eczema Product With Activated Oil (AO)

NCT05413395
View directory record Official record
Conditions
Eczema
Interventions
topical colloidal oatmeal formulation with a modified plant oil, topical colloidal oatmeal formulation
Other
Lead sponsor
GlycosBio, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Sep 28, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

NCT07337902
View directory record Official record
Conditions
Crohn's Disease (CD), Dysmenorrhea Primary
Interventions
Acetaminophen, Ibuprofen
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Phase 3 Interventional Results available

Actual Use Trial of Ibuprofen 400 mg

NCT02294019
View directory record Official record
Conditions
Patient Compliance
Interventions
Ibuprofen 400 mg caplet
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
25
States / cities
Hoover, Alabama • McCalla, Alabama • Mesa, Arizona + 22 more
Source: ClinicalTrials.gov public record
Updated May 29, 2016 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Comparison of Two Over the Counter Intravaginal Devices for the Treatment of Stress Urinary Incontinence

NCT06698627
View directory record Official record
Conditions
Stress Urinary Incontinence in Women
Interventions
Daily Disposable Continence Device, Monthly Disposable Continence Device
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

OTC Hearing Aid and MCI

NCT06112860
View directory record Official record
Conditions
Hearing Loss, Mild Cognitive Impairment, Alzheimer Disease and Related Dementias (ADRD)
Interventions
Over the counter hearing aid, Communication Strategies Information/Counseling
Device · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Evanston, Illinois • La Crosse, Wisconsin • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Opioid Analgesic Reduction Study

NCT04452344
View directory record Official record
Conditions
Opioid Use
Interventions
opioid-containing analgesic, two over-the-counter analgesics
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
1,815 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
5
States / cities
Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening Tool

NCT03936985
View directory record Official record
Conditions
Opioid Abuse, Prescription Drug Abuse (Not Dependent)
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
1,464 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Cincinnati, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional

Video Assisted Informed Consent for Lortab to Improve Patient Satisfaction and Knowledge

NCT01374295
View directory record Official record
Conditions
Non-critical Emergency Room Patients Receiving Lortab Medication or Prescription During Their Emergency Room Visit
Interventions
video, standard education
Other
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2014 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Opioid Prescribing Nudge

NCT04069403
View directory record Official record
Conditions
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior, Benzodiazepine Abuse, Benzodiazepine Dependent
Interventions
Automated Reports on prescription patterns for their patients
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
427 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional Results available

Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial

NCT03726476
View directory record Official record
Conditions
Abuses Over-The-Counter/Prescription Medications, Pain, Postoperative, Opioid Use, Physical Activity, Patient Dependence on
Interventions
Patient centered pre-op education, routine preop education
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Albuquerque, New Mexico • Rio Rancho, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Over-the-Counter Medication Usage

NCT00439348
View directory record Official record
Conditions
Drugs, Non-Prescription, Medication Systems
Interventions
Verbal advice, Prescription
Behavioral
Lead sponsor
AdventHealth
Other
Eligibility
19 Years to 50 Years · Female only
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2009 · Synced Sep 28, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

Innovations in Hearing Accessibility and Technology (IHAT) Study

NCT06689865
View directory record Official record
Conditions
Hearing Loss, Hearing Aids, OTC Hearing Aids
Interventions
HA-HCP, OTC-HCP, OTC-R, OTC-SF
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 28, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional

Social Network Overdose Prevention and Education Intervention

NCT06327061
View directory record Official record
Conditions
Drug Overdose
Interventions
Network overdose prevention, Standard of care health education
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Effects of Dietary Conditions on Drug Response

NCT04315961
View directory record Official record
Conditions
Healthy
Interventions
Blinded drug dose conditions
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 45 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 28, 2026, 6:32 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Clinical Evaluation of Skin Microbiome an Over-The-Counter (OTC) Drug for Atopic Dermatitis

NCT07146971
View directory record Official record
Conditions
Atopic Dermatitis (AD)
Interventions
OTC Drug for Atopic Dermatitis in Cream form
Drug
Lead sponsor
Good Molecules, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing Pharmacy Technician Educational Training for the Provision of Over-the-Counter Hearing Aids in Rural Alabama and Mississippi Pharmacies

NCT06864273
View directory record Official record
Conditions
Bilateral Hearing Loss, Health Services Research
Interventions
Pharmacy Technician Educational Training
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

This Was a Clinical Study Investigating the Moisturization and Desquamation Effect of AmLactin® Rapid Relief Restoring Lotion + Ceramides on Dry Skin in Healthy Female Volunteers. AmLactin® Rapid Relief is an Over-the-counter Cosmetic

NCT04085809
View directory record Official record
Conditions
Dry Skin
Interventions
AmLactin® Rapid Relief
Other
Lead sponsor
Sandoz
Industry
Eligibility
50 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 28, 2026, 6:32 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The Over The Counter Pill National Study

NCT05988983
View directory record Official record
Conditions
Contraception, Contraception Behavior, Contraceptive Usage, Health Care Utilization
Interventions
Availability of OTC contraceptive pill
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
12 Years to 51 Years · Female only
Enrollment
1,026 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 28, 2026, 6:32 PM EDT
Terminated Not applicable Interventional

Integrating Acupuncture Into the Management of Migraines

NCT01481103
View directory record Official record
Conditions
Migraine Headache
Interventions
Acupuncture
Procedure
Lead sponsor
National University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Oak Park, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Influence of Medication on Functional Connectivity

NCT03612713
View directory record Official record
Conditions
Prescription Drug Abuse (Not Dependent)
Interventions
Oxycodone Medication First, Placebo First
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Actual Use Trial of Tadalafil 5 mg

NCT06805513
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tadalafil 5 mg tablets with a digital tool.
Combination Product
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older · Male only
Enrollment
2,212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Enrolling by invitation Not applicable Interventional

T2D Intermittent Nonprescription Sensors for Informed Glucose Health Tracking

NCT07422831
View directory record Official record
Conditions
Type 2 Diabetes, Non Insulin Dependent Diabetes
Interventions
Periodic, over-the-counter continuous glucose monitoring
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 28, 2026, 6:32 PM EDT
Terminated Phase 2 Interventional

Effects of Pycnogenol on Cardiac Fibrosis and Diastolic Dysfunction in Aged Hypertensive Subjects

NCT00952627
View directory record Official record
Conditions
Cardiac Fibrosis, Diastolic Dysfunction
Interventions
Pycnogenol, Placebo
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
50 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Sep 28, 2026, 6:32 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Gastrointestinal Safety Evaluation of Two Over the Counter Analgesics

NCT01822665
View directory record Official record
Conditions
Gastrointestinal Mucosal Damage
Interventions
Ibuprofen, Paracetamol, Placebo
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 60 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2014 · Synced Sep 28, 2026, 6:32 PM EDT