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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:17 PM EDT

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Showing 145–168 of 504 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dysautonomia Clear all
Active, not recruiting Phase 2 Interventional

Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia

NCT06128356
View directory record Official record
Conditions
Familial Dysautonomia
Interventions
Dexmedetomidine Sublingual
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional

Abdominal and Lower Extremity Compression During Tilt Table Testing in Adolescent POTS Patients

NCT01795469
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome (POTS), Syncope
Interventions
Zoex compression garment
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 20, 2026, 1:17 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Mechanisms of Hypoglycemia Associated Autonomic Failure

NCT00678145
View directory record Official record
Conditions
Diabetes Mellitus, Hypoglycemia, Autonomic Failure
Interventions
naloxone, fructose, exercise, Morphine sulfate, Epinephrine
Drug · Dietary Supplement · Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 4 Interventional

Trial of Parkinson's And Zoledronic Acid

NCT03924414
View directory record Official record
Conditions
Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
Interventions
Zoledronic Acid 5Mg/Bag 100Ml Inj, Placebo
Drug · Other
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
60 Years and older
Enrollment
2,721 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
77
States / cities
Scottsdale, Arizona • Fayetteville, Arkansas • Little Rock, Arkansas + 58 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 1Phase 2 Interventional

The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease

NCT01676103
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Tyrosine, Placebo Comparator:Sugar Pill
Dietary Supplement · Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 20, 2026, 1:17 PM EDT
Active, not recruiting Not applicable Interventional

Water and the Gastropressor Response - Tachyphylaxis

NCT00580996
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
water high dose, water tiny dose
Other
Lead sponsor
Satish R. Raj
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Guided Imagery for Chronic Pain

NCT04849897
View directory record Official record
Conditions
Complex Regional Pain Syndromes, Back Pain
Interventions
Experimental: Virtual Reality Guided Imagery, Active Comparator: Audio Only Guided Imagery
Device · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 20, 2026, 1:17 PM EDT
Recruiting No phase listed Observational

Data Collection of Standard Care of Patients in the EMG Section

NCT05041387
View directory record Official record
Conditions
Neuropathy, Muscle Disorders, Dysautonomia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 110 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional Results available

Orthostatic Hypotension in Rehabilitation Patients

NCT00117585
View directory record Official record
Conditions
Hypotension, Orthostatic
Interventions
Treatment Phase 1, Treatment Phase 2, Treatment Phase 3
Other · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
341 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)

NCT02406586
View directory record Official record
Conditions
Hypertension, Diabetes
Interventions
Salsalate, Carvedilol, Placebo, Intralipid 20%
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 4 Interventional Results available

Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension

NCT00555880
View directory record Official record
Conditions
Hypotension, Orthostatic
Interventions
Midodrine hydrochloride, Placebo
Drug
Lead sponsor
Shire
Industry
Eligibility
19 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
11
States / cities
Fort Wayne, Indiana • Boston, Massachusetts • Ann Arbor, Michigan + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 20, 2026, 1:17 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Autonomic Determinants of POTS - Pilot1

NCT04050410
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Moxonidine, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 4 Interventional Results available

Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension

NCT01518946
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Midodrine HCl, Placebo
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
13
States / cities
Boca Raton, Florida • New Port Richey, Florida • Lenexa, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 20, 2026, 1:17 PM EDT
Completed No phase listed Observational

Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome

NCT05852210
View directory record Official record
Conditions
CRPS (Complex Regional Pain Syndromes)
Interventions
Infrared Imaging
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Active, not recruiting Phase 2 Interventional

Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)

NCT03775096
View directory record Official record
Conditions
REM Sleep Behavior Disorder, Pre-motor Parkinson Disease, Symptomatic Parkinson Disease
Interventions
Carvedilol
Drug
Lead sponsor
Michele Tagliati, MD
Other
Eligibility
50 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults

NCT05888142
View directory record Official record
Conditions
Pain, Chronic
Interventions
in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS

NCT03261570
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome (POTS), POTS, Orthostatic Intolerance
Interventions
Pyridostigmine, Digoxin, Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
15 Years to 30 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Hawthorne, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Not applicable Interventional

The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions

NCT04514354
View directory record Official record
Conditions
Cardiovascular Diseases, Post-Exercise Hypotension
Interventions
GEST
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 20, 2026, 1:17 PM EDT
Terminated Phase 1 Interventional Results available

Orthostatic Intolerance After Bariatric Surgery

NCT03808740
View directory record Official record
Conditions
Orthostatic Intolerance
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 20, 2026, 1:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PET Scan in Patients With Neurocardiologic Disorders

NCT00001418
View directory record Official record
Conditions
Autonomic Nervous System Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 20, 2026, 1:17 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways

NCT07775976
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities, His-Purkinje Disease, Arrhythmias, Cardiac, Rhythm Phenotypes, Myocardial Ischemia, Syncope, Syncope Recurrent, Syncope and Collapse, Seizure Disorder, Sleep Apnea Syndrome, Obstructive, Decision Support Systems, Clinical, Heart Failure - NYHA II - IV, Heart Failure (for Example, Fluid Overload), HRV, Cardiopulmonary, Sudden Cardiac Arrest, Cardiac Arrest (CA), Ventricular Arrhythmias and Cardiac Arrest, Ventricular Fibrillation, QT Dispersion, Atrial Cardiomyopathy
Interventions
COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
Device · Other
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Pasadena, California • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Not yet recruiting Not applicable Interventional

The Impact of Improved Vagal Function on Periaqueductal Gray Connectivity

NCT05618067
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
breathing exercise training
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 3 Interventional Results available

Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury

NCT02307565
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Midodrine, Placebo
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 20, 2026, 1:17 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Disease

NCT05487300
View directory record Official record
Conditions
Parkinson Disease, Orthostatic Hypotension
Interventions
Autonomic testing on and off levodopa
Drug
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 20, 2026, 1:17 PM EDT