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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dysthymia Disorder Clear all
Completed Not applicable Interventional

A Trial of Cognitive Behavioral Therapy in Familial Dysautonomia

NCT03013777
View directory record Official record
Conditions
Dysthymia, Anxiety Disorders, Familial Dysautonomia, Paroxysmal Hypertension, Autosomal Recessive Disease
Interventions
8-week CBT Program
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional

Medications for the Treatment of Dysthymic Disorder and Double Depression

NCT00234312
View directory record Official record
Conditions
Depression, Dysthymia
Interventions
escitalopram and sertraline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 28, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional Results available

Wellbutrin XL for Dysthymic Disorder

NCT00225251
View directory record Official record
Conditions
Dysthymic Disorder
Interventions
bupropion XL, Placebo
Drug · Other
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional Results available

Escitalopram in the Treatment of Dysthymic Disorder, Double Blind

NCT00220701
View directory record Official record
Conditions
Dysthymic Disorder
Interventions
Lexapro (escitalopram)
Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 10, 2015 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 3 Interventional Results available

Safety and Tolerability of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder

NCT00707980
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Vortioxetine
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 76 Years
Enrollment
836 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
38
States / cities
Beverly Hills, California • Irvine, California • Santa Ana, California + 35 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2013 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Not applicable Interventional Results available

Treating Depression Among Low-Income Patients With Cancer

NCT00565110
View directory record Official record
Conditions
Major Depression, Dysthymia
Interventions
ADAPt-C intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 27, 2026, 6:45 PM EDT
Terminated Not applicable Interventional Results available

Oxytocin Add-on for Stable Depressed Patients

NCT01211756
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
David Feifel
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Not applicable Interventional

Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive Symptoms

NCT01892124
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Type 2, Depression, Dysthymic Disorder
Interventions
Motivational Interviewing/Cognitive Behavioral-based Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms

NCT01189812
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia, Depression Not Otherwise Specified, Borderline Personality Disorder
Interventions
Lithium Carbonate, Placebo, Citalopram
Drug
Lead sponsor
Columbia Northwest Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
San Diego, California • Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 2 Interventional

Computerized Information-Processing Bias Retraining in Depressed Adolescents

NCT01147913
View directory record Official record
Conditions
Major Depression
Interventions
Computerized Information-Processing Bias Retraining, Attention Control Training
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional

Are Two Antidepressants a Good Initial Treatment for Depression?

NCT00296712
View directory record Official record
Conditions
Major Depression, Dysthymia, Depression NOS
Interventions
escitalopram + bupropion
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2012 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 1Phase 2 Interventional

The Efficacy of Parent Involvement in the Treatment of Adolescent Depression

NCT00883519
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder
Interventions
Interpersonal Psychotherapy for Depressed Adolescents, Interpersonal Psychotherapy for Depressed Adolescents and Parents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2012 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional Results available

Dichotic Listening as a Predictor of Medication Response in Depression

NCT00404755
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia
Interventions
escitalopram, bupropion, imipramine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced Sep 27, 2026, 6:45 PM EDT
Completed No phase listed Observational

Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence

NCT01528748
View directory record Official record
Conditions
Depressive Disorder, Major Depressive Disorder, Dysthymic Disorder, Alcohol-Related Disorders, Alcoholism
Interventions
Cognitive Behavioral Analysis System of Psychotherapy
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Dichotic Listening as a Predictor of Medication Response in Depression

NCT00296725
View directory record Official record
Conditions
Major Depression, Dysthymia, Depressive Disorder Not Otherwise Specified
Interventions
Fluoxetine, Imipramine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed No phase listed Observational

Implementation of Harmonized Depression Outcome Measures in a Primary Care Registry and a Mental Health Registry

NCT04235725
View directory record Official record
Conditions
Major Depression, Dysthymia
Interventions
Harmonized Depression Outcome Measures
Other
Lead sponsor
OM1, Inc.
Industry
Eligibility
18 Years and older
Enrollment
953 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Sep 27, 2026, 6:45 PM EDT
Recruiting Not applicable Interventional

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

NCT07028216
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia, Major Depressive Disorder, Persistent Depressive Disorder (Dysthymia)
Interventions
Mindful Self-Compassion
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 27, 2026, 6:45 PM EDT
Withdrawn Phase 4 Interventional

A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults

NCT01942187
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder Not Otherwise Specified (NOS)
Interventions
Aripiprazole, Bupropion, Problem Solving Therapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 3 Interventional

A Clinical Trial of IPT-A to Prevent Suicide in Depressed Adolescents With Suicidal Behavior

NCT01447602
View directory record Official record
Conditions
Unipolar Depression, Dysthymia
Interventions
IPT-A
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 19 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional

Treatment of Depression Following Multiple Brain Tests

NCT00296777
View directory record Official record
Conditions
Major Depression, Dysthymia
Interventions
Escitalopram, Bupropion, Imipramine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2012 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Not applicable Interventional

Group Therapy for Women Prisoners With Comorbid Substance Use and Depression

NCT00606996
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Depressive Disorder
Interventions
Group interpersonal psychotherapy (IPT-G), Psychoeducation on co-occurring disorders (PSYCHOED)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Phase 4 Interventional Results available

Duloxetine for Chronic Depression: a Double-blind Study

NCT00360724
View directory record Official record
Conditions
Dysthymic Disorder, Depressive Disorder NOS
Interventions
Duloxetine (Cymbalta)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
20 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2017 · Synced Sep 27, 2026, 6:45 PM EDT
Terminated Phase 4 Interventional Results available

L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults

NCT03761030
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia, Depression
Interventions
L-DOPA, Placebo Oral Tablet
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 27, 2026, 6:45 PM EDT
Completed Not applicable Interventional Results available

Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social Functioning

NCT01783080
View directory record Official record
Conditions
Persistent Depressive Disorder
Interventions
Behavioral Activation for return to work
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2017 · Synced Sep 27, 2026, 6:45 PM EDT