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ClinicalTrials.gov public records Last synced Oct 18, 2026, 3:20 PM EDT

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Showing 73–96 of 205 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dystonia Disorder Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

NCT01961297
View directory record Official record
Conditions
Spasmodic Dysphonia, Voice Tremor
Interventions
Sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2017 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational

Implantable Systems Performance Registry

NCT00959296
View directory record Official record
Conditions
Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
Interventions
Various
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
Not listed
Enrollment
10,981 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
43
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Aliso Viejo, California + 40 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 18, 2026, 3:20 PM EDT
Recruiting No phase listed Observational

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

NCT04071847
View directory record Official record
Conditions
Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Interventions
Deep Brain Stimulation (DBS)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
23
States / cities
Tucson, Arizona • Los Angeles, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Recruiting Phase 2 Interventional

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

NCT07304089
View directory record Official record
Conditions
Dystonia
Interventions
VIM0423, VIM0423 Placebo
Drug
Lead sponsor
Vima Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
38
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Sun City, Arizona + 32 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Not applicable Interventional

Exercise Training in Dystonia

NCT03318120
View directory record Official record
Conditions
Dystonia
Interventions
Progressive Resistance Training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp

NCT02015039
View directory record Official record
Conditions
Dystonia
Interventions
BoNT Injections, Occupational Therapy
Drug · Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 100 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging of Dystonia

NCT02046447
View directory record Official record
Conditions
Primary Cervical Dystonia, DYT 1 Dystonia
Interventions
Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control), DYT 1 Dystonia
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
7 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational

Telemedicine Follow-up for Patients With Cervical Dystonia Treated With Neurotoxin Injections

NCT03969537
View directory record Official record
Conditions
Cervical Dystonia, Telemedicine
Interventions
Telemedicine follow-up visit
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Early Phase 1 Interventional

Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing

NCT02504905
View directory record Official record
Conditions
Writer's Cramp, Healthy Volunteers, Cervical Dystonia
Interventions
TMS
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 2 Interventional Results available

Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand

NCT02107261
View directory record Official record
Conditions
Dystonia
Interventions
incobotulinumtoxin A, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational

Physiological Brain Atlas Development

NCT01210534
View directory record Official record
Conditions
Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder, Depression
Interventions
No intervention
Other
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 90 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of Dopamine Receptors in Primary Focal Dystonias

NCT01373840
View directory record Official record
Conditions
Healthy, Focal Dystonias
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 1Phase 2 Interventional Results available

An Open-label Study to Define the Safety, Tolerability and Clinical Activity of Deutetrabenazine (AUstedo) in Adult Study Subjects With DYsTonia

NCT04173260
View directory record Official record
Conditions
Dystonia, Primary
Interventions
Deutetrabenazine 6 MG
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 18, 2026, 3:20 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Brain Anatomy in Dystonia

NCT00031369
View directory record Official record
Conditions
Dystonia, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 4 Interventional

Investigation of Lithium on Signal Transduction, Gene Expression and Brain Myo-Inositol Levels in Manic Patients

NCT00870311
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Lithium Carbonate
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2004
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2009 · Synced Oct 18, 2026, 3:20 PM EDT
Enrolling by invitation Phase 2 Interventional

Accelerating TMS for Cervical Dystonia

NCT06328114
View directory record Official record
Conditions
Isolated Cervical Dystonia
Interventions
Transcranial Magnetic Stimulation (TMS), Placebo, trihexyphenidyl 10mg
Device · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Function in Focal Dystonia

NCT00102999
View directory record Official record
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 18, 2026, 3:20 PM EDT
Recruiting Not applicable Interventional

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

NCT06036199
View directory record Official record
Conditions
Cerebral Palsy, Dyskinetic, Secondary Dystonia
Interventions
Focused Ultrasound Pallidotomy
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
8 Years to 22 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 2 Interventional

Deep Brain Stimulation for Cervical Dystonia

NCT00105430
View directory record Official record
Conditions
Dystonia, Generalized Primary Dystonia
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
7 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 6, 2006 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 3 Interventional

Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1)

NCT03608397
View directory record Official record
Conditions
Cervical Dystonia
Interventions
DaxibotulinumtoxinA for injection, Placebo
Biological
Lead sponsor
Revance Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
44
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Fountain Valley, California + 38 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 18, 2026, 3:20 PM EDT
Not yet recruiting Phase 1 Interventional

Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor

NCT07041203
View directory record Official record
Conditions
Spasmodic Dysphonia, Laryngeal Dystonia, Voice Tremor
Interventions
sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 18, 2026, 3:20 PM EDT
Completed Phase 3 Interventional Results available

Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia

NCT00257660
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Botulinum toxin type A, Placebo
Biological · Drug
Lead sponsor
Ipsen
Industry
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
18
States / cities
Phoenix, Arizona • Fountain Valley, California • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 18, 2026, 3:20 PM EDT
Active, not recruiting Not applicable Interventional

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

NCT03582891
View directory record Official record
Conditions
Parkinson Disease, Dystonia
Interventions
Summit RC+S for Motor, 8-week pilot trial of Closed-loop vs. Open-loop Stimulation, Summit RC+S for Sleep
Device · Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 18, 2026, 3:20 PM EDT