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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 373 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: E Cig Use Clear all

Conditions: Tobacco-flavored EC, Sweet-Cooling EC, Sweet Non-cooling EC
Interventions: Brief individual counseling sessions; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 21 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Nicotine Dependence, Nicotine Vaping
Interventions: (S)-Nicotine, (R)- nicotine, Racemic nicotine; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Volunteers, Smoking
Interventions: Use electronic cigarette or smoke conventional cigarette; Other
Lead sponsor: British American Tobacco (Investments) Limited; Industry
Eligibility: 22 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Burbank, California

Conditions: Cannabis Use, Tobacco, Biomarkers
Interventions: Cannabis (THC), Tobacco Cigarette; Drug
Lead sponsor: Hannah Harris; Other
Eligibility: 18 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Smoking, Cigarette
Interventions: JUUL, Treatment As Usual; Device · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years to 99 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Healthy Volunteers
Interventions: Myblu flavor A_2.4, Myblu flavor B_2.4, Myblu flavor C_2.4, Myblu flavor D_2.4, Myblu flavor E_1.2, Myblu flavor F_1.2, Myblu flavor G_2.4, Myblu flavor H_2.4; Other
Lead sponsor: Fontem US LLC; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: E-cigarette Use, Smoking Behaviors
Interventions: JUUL E-Cigarette Device; Device
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Electronic Cigarette Use
Interventions: Tobacco product administration and assessment; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Vaping Behaviors
Interventions: Label with text health warning, Label with pictorial health warning, Label with neutral statements about vaping; Other
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 1,369 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: COPD
Interventions: E-cigarette (EC), Nicotine Replacement Therapy (NRT), Smoking Harm Reduction Counseling Sessions; Other · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 75 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Smoking, Electronic Cigarette Use, Substance Use
Interventions: CC+ECIG Condition, CC Condition, Sham Condition; Other
Lead sponsor: University of Houston; Other
Eligibility: 18 Years and older
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Tobacco Use Disorder, Nicotine Dependence
Interventions: Counseling, Contingency management, Text-based support; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 25 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Biomarkers
Interventions: E-Cig Zero Nicotine, E-Cig 24mg Nicotine; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Nicotine Labeling for E-cigarettes
Interventions: Updated Labeling; Other
Lead sponsor: Yale University; Other
Eligibility: 14 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Cessation, Electronic Nicotine Delivery Systems
Interventions: Vaping - Fruit flavored ENDS, Biospecimen Collection, Vaping - tobacco flavored ENDS; Other · Procedure
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years and older
Enrollment: 286 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking Cessation, Vaping Cessation
Interventions: Cytisinicline; Drug
Lead sponsor: Achieve Life Sciences; Industry
Eligibility: 18 Years and older
Enrollment: 479 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 29
States / cities: Mobile, Alabama • Tempe, Arizona • Little Rock, Arkansas + 26 more

Conditions: Depressive Symptoms, Depression, Adolescent Behavior
Interventions: Behavioral Activation Therapy app, Treatment as Usual; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 16 Years to 20 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Electronic Cigarettes
Interventions: E-cigarette with sweetness type 1 and pronation level 1, E-cigarette with sweetness type 1 and pronation level 2, E-cigarette with sweetness type 2 and pronation level 1, E-cigarette with sweetness type 2 and pronation level 2; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Vaping
Interventions: Exposure to Influencer Age and Context Variations in E-Cigarette Marketing; Other
Lead sponsor: University of Southern California; Other
Eligibility: 14 Years to 17 Years
Enrollment: 6,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Heavy Metal Exposure From Vaping
Interventions: Non-Interventional Study; Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 29 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: THC, Cannabis, Cannabis Use, Cannabis Smoking, Tobacco Use, Vaping
Interventions: Cannabis, Nicotine, Pax Loose Leaf Vaporizer, Placebo Marijuana; Drug · Device · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 65 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Schizophrenia and Related Disorders
Interventions: e-cigarette, brand name JUUL; Device
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions: Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Nicotine Dependence
Interventions: one time exposure to e-cig with nicotine, One time exposure to e-cigarette without nicotine, one time exposure to empty e-cigarette; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

E-cigarette Nicotine Pharmacokinetic Study

Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis

Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures

A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes

Effects of E-Cigarettes in Menthol Smokers

Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)

Impact of E-cigarette Device Warnings

Electronic Cigarettes as a Harm Reduction Strategy Among Patients With COPD

Dual Use Approach Bias Training for Nicotine Addiction

Young Adult Tobacco/Nicotine and Cannabis Co-use

Changes in Biomarkers Associated With Use of Electronic Cigarettes

Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes

Flavored Electronic Nicotine Delivery Systems to Lower Smoking and Exposure to Tobacco Toxicants Among Cigarette Smokers Interested in Quitting, REFLECT Trial

Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers

Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents

Determination of Liquid Flavor and Nicotine Form Outcomes

E-cigarette Social Media Marketing and Its Perceptions by Youth

Examining Heavy Metal Exposure and Respiratory Health in Young Adult Electronic Cigarette Users

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

Role of an E-cigarette on Smoking Displacement in Smokers With Schizophrenia

Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

E-Cigarettes and SNA