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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:06 AM EST

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Showing 25–48 of 373 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: E Cig Use Clear all

Conditions: E-Cigarette Use, E-cigarette Use/Vaping Prevention, Vaping Teens, Vaping, Adolescent Behavior, Nicotine, Tobacco
Interventions: Influencer Intervention Videos, Public Domain Messaging Videos, Influencer Control Videos; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 13 Years to 21 Years
Enrollment: 2,556 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Vaping, E-cigarette Use, Electronic Cigarette Use
Interventions: Vape Messaging Intervention; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 24 Years
Enrollment: 569 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Abuse Tobacco, Exposure
Interventions: Biospecimen Collection, Survey Administration, Vaping Topography, Participant's Own Preferred E-cigarette, Nicotine E-cigarette, 6-methyl-nicotine (metatine) e-cigarette; Other · Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years to 34 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Electronic Cigarette Use, E-Cig Use, Cigarette Smoking, Cigarette Use, Electronic
Interventions: E-cigarette e-liquid self-administration; Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Nicotine Vaping, Nicotine Dependence
Interventions: Nicotine, Placebo; Drug · Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Nicotine Dependence, Tobacco Toxicity, Nicotine Dependence, Cigarettes, Cardiovascular Risk Factor, Nicotine Withdrawal
Interventions: SREC; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Vaping
Interventions: Discussion of point-of-care ultrasound lung findings; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 18 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Hookah Smoking, Secondhand Aerosol, Vascular Stiffness, Vaping
Interventions: Combustible Hookah Smoke, Electronic Hookah Aerosol, Clean Room Air; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 49 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Vaping
Interventions: Control task and Trier Social Stress Task; Other
Lead sponsor: Clemson University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Smoking Cessation, Smoking
Interventions: smokeSCREEN web-based game; Device
Lead sponsor: Yale University; Other
Eligibility: 10 Years to 16 Years
Enrollment: 560 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking, Asthma, Electronic Cigarette Use, Cigarette Smoking
Interventions: Nicotine; Other
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Electronic Cigarettes
Interventions: E-cigarette Lab Session 15 watts, 10 mg nicotine, E-cigarette Lab Session 15 watts, 30 mg nicotine, E-cigarette Lab Session 30 watts, 10 mg nicotine, E-cigarette Lab Session 30 watts, 30 mg nicotine, Own Brand Session - E-cigarette, Own Brand Session - E-cigarette/Cigarette; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cigarette Smoking, Addiction, E Cig Use
Interventions: E cigarettes, Nicotine Replacement Therapy; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Health Behavior
Interventions: Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor; Drug
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 55 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Tobacco Use
Interventions: Click City®: Tobacco, Usual Tobacco Curriculum; Other
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.; Industry
Eligibility: 9 Years to 12 Years
Enrollment: 2,673 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Springfield, Oregon

Conditions: Tobacco Use
Interventions: e-cigarette, Nicotine patch, Nicotine lozenge; Behavioral · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Former Smoker, Non-Smoker
Interventions: D10-phenanthrene; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions: AD IT UP media literacy intervention, Usual health education curriculum; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 13 Years to 17 Years
Enrollment: 318 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Electronic Cigarette Use, Cigarette Smoking, Cigarette Use, Electronic, Vaping
Interventions: Control Marketing Strategies, Experimental Marketing Strategies; Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 601 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Nicotine E-Cigarette Use
Interventions: Water Concentration 1, Water Concentration 2, Water Concentration 3, Water Concentration 4; Other
Lead sponsor: Yale University; Other
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Dependence, Tobacco Toxicity, Cardiovascular Risk Factors
Interventions: Standardized Research E-Cigarette (SREC), Over the Counter E-Cigarette (EC), Biological Samples, Smoking-related Questionnaires; Other · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: E Cigarette Use, Cessation, Tobacco, Cessation, Nicotine
Interventions: Nicotine Replacement Therapies, Brief Behavioral Counseling; Drug · Behavioral
Lead sponsor: West Virginia University; Other
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Greenville, North Carolina • Morgantown, West Virginia

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Nicotine Replacement, Questionnaire Administration, Electronic Cigarette; Drug · Other · Device
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 169 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Vaping Behaviors
Interventions: Health Impacts of E-cigarettes, Mind Matters: The Body's Response to Nicotine, Tobacco, and Vaping, The Villainous Vape; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 12 Years to 17 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Search by objective public record fields.

Understanding Vape Counter-Marketing Study

PACE Vape Messaging Study

Perceptions of Vaping Products

Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2

Nicotine and Pavlovian Bias

Cigarette Harm Reduction With Electronic Cigarette Use

Point-of-Care Ultrasound (POCUS) Findings and Impact on Vaping

Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol

Modeling Stress-precipitated Vaping Behavior

Implementation and Dissemination of an Evidence-Based Tobacco Product Use Prevention Videogame Intervention With Adolescents

E-cigarettes for Harm Reduction in Adults With Asthma

Effects of E-Cigarette Power and Nicotine Content in Dual Users and Vapers

Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder

Effects of Electronic Cigarettes on Nicotine Concentrations

Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products

Quit or Switch: E-cigarette Study

Vaped Phenanthrene

Pittsburgh and Rural Area High School Tobacco Prevention

Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 1

Water Content in E-Liquids

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)

Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use

Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes

The Villainous Vape: Advancing Vaping Prevention Among Adolescents Through a Comic Book