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ClinicalTrials.gov public records Last synced Sep 16, 2026, 2:31 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Early Cancer Detection Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters

NCT00006445
View directory record Official record
Conditions
Down Syndrome, Chromosome Abnormalities
Interventions
Ultrasound, Serum screen
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
16 Years to 45 Years · Female only
Enrollment
38,000 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
10
States / cities
Denver, Colorado • Boston, Massachusetts • Royal Oak, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2007 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Results available

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography

NCT02306265
View directory record Official record
Conditions
Breast Cancer, Tumors, Breast, Cancer Screening
Interventions
FFDM, DBT
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
30 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Royal Oak, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Sep 16, 2026, 2:31 AM EDT
Not yet recruiting No phase listed Observational

Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization

NCT07768046
View directory record Official record
Conditions
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Lung Neoplasms, Lung Cancer Screening
Interventions
Multiparametric chest MRI with diffusion-weighted imaging
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Interactive Intervention to Increase CRCS

NCT01084746
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
PC-based tailored intervention, Printed educational materials
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 64 Years
Enrollment
1,224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Sep 16, 2026, 2:31 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Multi-Cancer Early Detection (MCED) of Firefighters

NCT05780957
View directory record Official record
Conditions
Cancer
Interventions
MCED
Other
Lead sponsor
Vincere Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Phase 2 Interventional

Sputum Cytology in Screening Heavy Smokers For Lung Cancer

NCT00103363
View directory record Official record
Conditions
Lung Cancer
Interventions
cytology specimen collection procedure, physiologic testing, annual screening, study of high risk factors
Other · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
25 Years and older
Enrollment
3,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 1994
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 6, 2014 · Synced Sep 16, 2026, 2:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients

NCT05716477
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Biospecimen Collection, Survey Administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
45 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Traditional Print Communication Methods, Simple Electronic Communication Methods, or Usual Care in Increasing How Often Older Women Undergo Colorectal Cancer Screening

NCT00459030
View directory record Official record
Conditions
Colorectal Cancer
Interventions
educational intervention via internet, educational intervention mailed, No additional educational intervention
Other
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
50 Years and older · Female only
Enrollment
904 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2013 · Synced Sep 16, 2026, 2:31 AM EDT
Completed No phase listed Observational

Clinical Validation of a Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer (VERIFI)

NCT06947395
View directory record Official record
Conditions
Cancer of the Pancreas, Pancreatic Cancer, Pancreas Neoplasms, Pancreatic Carcinoma Stage I, Pancreatic Carcinoma Stage II
Interventions
PancreaSure
Diagnostic Test
Lead sponsor
Immunovia, Inc.
Industry
Eligibility
45 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
6
States / cities
Scottsdale, Arizona • New York, New York • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Results available

Effectiveness and Implementation of mPATH-CRC

NCT03843957
View directory record Official record
Conditions
Colorectal Cancer, Cancer, Rectum Cancer, Colon Cancer
Interventions
mPATH-CRC, mPATH-Checkin, "high touch" Implementation strategy, "low touch" Implementation Strategy
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
77,145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Sep 16, 2026, 2:31 AM EDT
Recruiting Not applicable Interventional

St. Joseph's HPV Self-sampling: Offering a Self-sampling Option in Clinic

NCT05092022
View directory record Official record
Conditions
Cervical Cancer Screening
Interventions
Evalyn Self-Sampling Brush
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional

Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease

NCT02890979
View directory record Official record
Conditions
Barrett Esophagus, Dysplasia, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Gastroesophageal Reflux Disease, Metaplasia
Interventions
Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Swallowable Sponge Cell Sampling Device
Other · Device
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Non-inferiority Evaluation of a Smart-phone Based Cervical Imaging Device.

NCT05388162
View directory record Official record
Conditions
Cervical Cancer
Interventions
Mobile colposcope
Device
Lead sponsor
Scripps Health
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.

NCT02754661
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
COLON Capsule endoscopy, Computed Tomographic Colonography
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
50 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
13
States / cities
Mobile, Alabama • Jacksonville, Florida • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Skin Cancer Early Detection and Treatment in Primary Care

NCT05675709
View directory record Official record
Conditions
Cutaneous Melanoma
Interventions
Training and Education
Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 16, 2026, 2:31 AM EDT
Enrolling by invitation No phase listed Observational

Real-world Effectiveness of HPV Vaccine in Women Living With HIV and Its Impact on Cervical Cancer Screening Accuracies

NCT06144229
View directory record Official record
Conditions
Hiv, Hpv
Interventions
Self-Collection HPV testing kit from Abbott
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 40 Years · Female only
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
9
States / cities
Denver, Colorado • Miami, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 16, 2026, 2:31 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Life Expectancy-informed Colorectal Cancer Screening

NCT07141901
View directory record Official record
Conditions
Colorectal Cancer Control and Prevention
Interventions
Decision Tool
Behavioral
Lead sponsor
Kathryn Martinez
Other
Eligibility
76 Years and older
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 16, 2026, 2:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Breath Test for Early Detection of Lung Cancer

NCT00639067
View directory record Official record
Conditions
Lung Neoplasms
Interventions
Breath Collection Apparatus
Device
Lead sponsor
Menssana Research, Inc.
Industry
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
4
States / cities
Newark, Delaware • Orlando, Florida • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interventions to Improve Colorectal Cancer Screening

NCT00692211
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Mailed fecal occult blood tests, Mailed fecal immunochemical tests
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 80 Years
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 16, 2026, 2:31 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Early Onset Colorectal Cancer Detection

NCT06342401
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Cancer Stage IV, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Neoplasms Malignant
Interventions
ENCODE
Diagnostic Test
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 16, 2026, 2:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Test Up Now Education Program

NCT04304001
View directory record Official record
Conditions
Colorectal Cancer Screening
Interventions
Community Health Advisor, Usual care
Behavioral
Lead sponsor
Florida A&M University
Other
Eligibility
45 Years to 64 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 16, 2026, 2:31 AM EDT
Completed No phase listed Observational

Alinity m HR HPV Specimen Collection Study From Women Undergoing Routine Cervical Cancer Screening

NCT04746872
View directory record Official record
Conditions
Human Papillomavirus
Interventions
Alinity m HR HPV
Diagnostic Test
Lead sponsor
Abbott Molecular
Industry
Eligibility
25 Years and older · Female only
Enrollment
14,935 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
63
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 46 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2024 · Synced Sep 16, 2026, 2:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Liquid Biopsy for Early Non-small Lung Cancer Detection

NCT05462795
View directory record Official record
Conditions
Non Small-cell Lung Cancer
Interventions
Liquid biopsy for aberrant DNA methylation analysis - Indeterminate pulmonary nodule, Liquid biopsy for aberrant DNA methylation analysis - Known lung cancer for surgical resection, Liquid biopsy for aberrant DNA methylation analysis - Healthy volunteer, Liquid biopsy for aberrant DNA methylation analysis - Benign lung disease
Diagnostic Test
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 16, 2026, 2:31 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Serum IGF-II and Cancer: Can IGF II Levels be Used to Monitor and Screen Patients Specifically for Cervical Cancer

NCT01371695
View directory record Official record
Conditions
Cervical Cancer, Cervical Intraepithelial Neoplasia II, Cervical Intraepithelial Neoplasia III
Interventions
Not listed
Lead sponsor
Onconix, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2011 · Synced Sep 16, 2026, 2:31 AM EDT