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ClinicalTrials.gov public records Last synced Oct 25, 2026, 2:21 PM EDT

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Showing 1–24 of 223 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Eclampsia Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Effects of High Altitude on AMPK Activation

NCT02391519
View directory record Official record
Conditions
Pregnancy, IUGR, Preeclampsia
Interventions
Collection of myometrial, cord blood, and placental tissue samples
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 25, 2026, 2:21 PM EDT
Active, not recruiting No phase listed Observational

MIRACLE of LIFE Study

NCT06074601
View directory record Official record
Conditions
Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane, Preeclampsia, HELLP, Gestational Hypertension, Gestational Diabetes Mellitus in Pregnancy, Small for Gestational Age at Delivery, Intrauterine Growth Restriction
Interventions
Mirvie Predictive Test for Adverse Pregnancy Outcomes
Diagnostic Test
Lead sponsor
Mirvie
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Timeline
2021 – 2025
U.S. locations
10
States / cities
San Diego, California • Orlando, Florida • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 25, 2026, 2:21 PM EDT
Not listed Early Phase 1 Interventional

Use of Impedance Cardiography to Decrease the Risk of Pre-eclampsia in Obese Patients

NCT03105661
View directory record Official record
Conditions
Obesity, Morbid, Preeclampsia
Interventions
Labetalol Hydrochloride 200 mg, NIFEdipine 60 mg, Atenolol 25 mg
Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 51 Years · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 25, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women

NCT02527018
View directory record Official record
Conditions
Preeclampsia, Maternal, Hypertension, Pregnancy
Interventions
Sphygmomanometer
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 25, 2026, 2:21 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia

NCT06157580
View directory record Official record
Conditions
Preeclampsia
Interventions
Compound 21, Angiotensin II
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Oct 25, 2026, 2:21 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Non-Invasive Preeclampsia Screening and Biobank

NCT06643741
View directory record Official record
Conditions
Preeclampsia (PE)
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
6,550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
21
States / cities
Glendale, Arizona • Newark, Delaware • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 25, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Practice Pattern Changes and Clinical Utility of a Novel Test for Preeclampsia

NCT04204018
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
Experimental Arm
Other
Lead sponsor
Qure Healthcare, LLC
Industry
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 25, 2026, 2:21 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Preeclampsia: A Marker for Future Cardiovascular Risk in Women

NCT01519297
View directory record Official record
Conditions
Preeclampsia, Pregnancy Induced Hypertension
Interventions
Irbesartan
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Oct 25, 2026, 2:21 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Characterization and Epigenetics of Post-Partum Preeclampsia

NCT02935556
View directory record Official record
Conditions
Post Partum Pre-eclampsia
Interventions
no intervention
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
New York, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 25, 2026, 2:21 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia

NCT07430254
View directory record Official record
Conditions
Pre-Eclampsia, Severe, Pregnancy
Interventions
Noninvasive finger plethysmographic cardiac output monitoring, Standard transthoracic echocardiographic assessment
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 25, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

BioThrax® (Anthrax) Vaccine in Pregnancy Registry

NCT01653392
View directory record Official record
Conditions
Pregnancy Complications, Pregnancy Outcome, Congenital Abnormalities
Interventions
Observational Intervention
Biological
Lead sponsor
Emergent BioSolutions
Industry
Eligibility
Female only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 25, 2026, 2:21 PM EDT
Completed No phase listed Observational

Impedance Cardiographic (ICG) Assessment of Pregnant Women With Severe Hypertension to Assess Impact of Standard Therapy

NCT01248169
View directory record Official record
Conditions
Pregnancy; Proteinuria, With Hypertension (Severe Pre-eclampsia), Delivery; Proteinuria, With Gestational Hypertension (Pre-eclampsia, Severe), Pregnancy; Hypertension, Gestational Hypertension, With Albuminuria (Severe Pre-eclampsia)
Interventions
Not listed
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Dec 12, 2013 · Synced Oct 25, 2026, 2:21 PM EDT
Completed Not applicable Interventional Results available

Remote BP Monitoring in the PP Period

NCT03728790
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy
Interventions
Remote Patient Monitoring
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 1, 2025 · Synced Oct 25, 2026, 2:21 PM EDT
Active, not recruiting Not applicable Interventional

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

NCT02412696
View directory record Official record
Conditions
Obstructive Sleep Apnea, Pregnancy, Obesity, Preeclampsia, Sleep
Interventions
Positive Airway Pressure, Nasal Dilator Strips
Device · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 25, 2026, 2:21 PM EDT
Recruiting Phase 2 Interventional

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

NCT06333652
View directory record Official record
Conditions
Preeclampsia
Interventions
Ravulizumab
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 25, 2026, 2:21 PM EDT
Terminated Phase 4 Interventional Results available

Phenylephrine Versus Ephedrine in Pre-eclampsia

NCT02025426
View directory record Official record
Conditions
Pre-eclampsia
Interventions
Phenylephrine, Ephedrine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 25, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients

NCT01261884
View directory record Official record
Conditions
Hypertension, Pregnancy, Preeclampsia, Exercise
Interventions
Exercise support, Exercise intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Oct 25, 2026, 2:21 PM EDT
Terminated Phase 4 Interventional Results available

Postpartum Management of Gestational Hypertensive Disorders Using Furosemide

NCT04343235
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced
Interventions
furosemide, labetalol
Drug
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 25, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy

NCT05826925
View directory record Official record
Conditions
Hypertension, Pregnancy Induced, Hypertension Complicating Pregnancy, Preeclampsia, Cardiovascular Diseases, Patient Engagement
Interventions
Decision aid
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 25, 2026, 2:21 PM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

NCT04551807
View directory record Official record
Conditions
Pregnancy Related, Pre-Eclampsia
Interventions
Modified natural cycle, Programmed cycle
Procedure
Lead sponsor
JHSPH Center for Clinical Trials
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
788 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
15
States / cities
San Francisco, California • Sunnyvale, California • Orange, Connecticut + 12 more
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 25, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Thoracic Ultrasonography for Pulmonary Edema in Patients With Pre-Eclampsia

NCT02357264
View directory record Official record
Conditions
Pre-eclampsia
Interventions
Ultrasound
Device
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 25, 2026, 2:21 PM EDT
Recruiting Phase 2 Interventional

Aspirin for Postpartum Patients With Preeclampsia

NCT05924971
View directory record Official record
Conditions
Preeclampsia Postpartum
Interventions
Aspirin 81Mg Ec Tab
Drug
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 25, 2026, 2:21 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia

NCT03863639
View directory record Official record
Conditions
Pre-Eclampsia, Neurocognitive Dysfunction
Interventions
Neuroimaging Procedures, Neuropsychological Assessment Procedures
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Oct 25, 2026, 2:21 PM EDT
Not yet recruiting Phase 4 Interventional

Biomarkers in Management of Post Partum Preeclampsia

NCT07478055
View directory record Official record
Conditions
Preeclampsia Severe, Preeclampsia Postpartum
Interventions
Magnesium Sulfate
Drug
Lead sponsor
Alexander Harrison
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 25, 2026, 2:21 PM EDT