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ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:47 PM EDT

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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Elderly Persons Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD

NCT06055322
View directory record Official record
Conditions
Suicide, Depression, Caregiver Burden, Physical Health, Inflammation
Interventions
Adapted Dialectical Behavior Therapy
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years to 120 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Active, not recruiting Phase 2 Interventional

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

NCT04761770
View directory record Official record
Conditions
Myelodysplastic Syndrome, Myeloproliferative Neoplasms, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia, Myelodysplastic/Myeloproliferative Overlapping Syndrome
Interventions
Geriatric assessment (GA) pre-transplant, conditioning regimen, Allogeneic CD34+ selected stem cells
Other · Drug · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
60 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acceptance and Commitment Therapy for Aging People Living With HIV in Chronic Pain

NCT03699020
View directory record Official record
Conditions
HIV/AIDS, Chronic Pain
Interventions
Acceptance and Commitment Therapy (ACT), Chronic Pain Education
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Results available

Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia

NCT01363258
View directory record Official record
Conditions
Care-resistant Behavior, Dementia
Interventions
Care-resistant mouth care (MOUTh), Evidence-based mouth care
Behavioral · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Bellefonte, Pennsylvania • Harrisburg, Pennsylvania • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia

NCT05658328
View directory record Official record
Conditions
Caregiver Burden, Depression, Cognitive Impairment
Interventions
SHARP - Physical and social activity
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Two Exercise Interventions to Improve Gait in Older Persons

NCT01076413
View directory record Official record
Conditions
Gait
Interventions
skill based exercise, aerobic conditioning
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Metformin Effect on Brain Function in Insulin Resistant Elderly People

NCT03733132
View directory record Official record
Conditions
Insulin Resistance, Obesity, Obesity, Abdominal
Interventions
Metformin Hydrochloride, Placebo Oral Tablet
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 18, 2024 · Synced Oct 17, 2026, 7:47 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)

NCT05573555
View directory record Official record
Conditions
Breast Cancer
Interventions
ARV-471, Ribociclib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
20
States / cities
Palo Alto, California • San Francisco, California • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

CAPABLE Care + Connect

NCT07123298
View directory record Official record
Conditions
Social Isolation in Older Adults, Social Isolation or Loneliness, Social Isolation, Quality of Life, Disability Physical, Homebound Persons
Interventions
CAPABLE Care + Connect - Open Label Pilot, CAPABLE Care + Connect - Pilot
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 1Phase 2 Interventional

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

NCT06125522
View directory record Official record
Conditions
Breast Cancer
Interventions
vepdegestrant, Samuraciclib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
19
States / cities
Fayetteville, Arkansas • Rogers, Arkansas • Springdale, Arkansas + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Not listed Not applicable Interventional

Telephone Counseling to Enhance the Quality and Safety of Romantic and Sexual Relationships in People Living and Aging With HIV

NCT03004170
View directory record Official record
Conditions
HIV Seropositivity
Interventions
Telephone-Administered Motivational Interviewing Plus Behavioral Skills Training, Telephone-Administered Coping Effectiveness Training
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 17, 2026, 7:47 PM EDT
Completed No phase listed Observational

Delirium in Persons With Dementia

NCT01394328
View directory record Official record
Conditions
Delirium Superimposed on Dementia
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Enhancing Cognition in Older Adults

NCT03653351
View directory record Official record
Conditions
Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Effect of Neuromuscular Electrical Stimulation (NMES)

NCT00765739
View directory record Official record
Conditions
Muscle Fiber Atrophy, Type II
Interventions
Neuromuscular electrical stimulation, voluntary strengthening exercise
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2013 · Synced Oct 17, 2026, 7:47 PM EDT
Terminated Phase 3 Interventional Results available

A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People

NCT01259297
View directory record Official record
Conditions
Cardiovascular Events
Interventions
Aliskiren, Amlodipine, Hydrochlorothiazide (HCTZ), Placebo for Aliskiren, Placebo for Amlodipine, Placebo for Hydrochlorothiazide (HCTZ)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
65 Years and older
Enrollment
2,336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • Northridge, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional

Ryan Companion Robot for Assisting Elderly People With Alzheimer's Disease

NCT05052866
View directory record Official record
Conditions
Alzheimer Disease, Early Onset
Interventions
Social Robot
Behavioral
Lead sponsor
DreamFace Technologies, LLC
Industry
Eligibility
65 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 2 Interventional

Comparison of Subacute and Hospital Based Rehabilitation Care

NCT00038363
View directory record Official record
Conditions
Aging
Interventions
Rehabilitation, Subacute care
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Individual Differences in Working Memory Training and Transfer in Older Adults

NCT05396586
View directory record Official record
Conditions
Cognitive Change
Interventions
N-back, Span, Multisensory
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
50 Years to 85 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Irvine, California • Riverside, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Oct 17, 2026, 7:47 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Precision Microbiota Interventions for Senoreduction Trial

NCT07462767
View directory record Official record
Conditions
HIV Infections, Alcohol Drinking, Aging, Immunosenescence
Interventions
Limosilactobacillus reuteri, Blueberry extract
Dietary Supplement
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
40 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 4 Interventional Results available

Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)

NCT01238536
View directory record Official record
Conditions
Spinal Stenosis, Low Back Pain
Interventions
Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection, Epidural local anesthetic injection
Procedure · Drug
Lead sponsor
University of Washington
Other
Eligibility
50 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
10
States / cities
Redwood City, California • Roseville, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Phase 1 Interventional

Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults

NCT01499706
View directory record Official record
Conditions
Unsafe Sex
Interventions
1-session of telephone-administered motivational interviewing, 4-session telephone-administered motivational interviewing
Behavioral
Lead sponsor
Ohio University College of Osteopathic Medicine
Other
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 26, 2011 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Branched Chain Amino Acids on Muscle

NCT00170144
View directory record Official record
Conditions
Healthy
Interventions
Branchamin 4%
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 15, 2011 · Synced Oct 17, 2026, 7:47 PM EDT
Recruiting Not applicable Interventional

ALIGN for Older Adults With Cancer in SNFs

NCT06616298
View directory record Official record
Conditions
Advanced Cancer
Interventions
Assessing and Listening to Individual Goals and Needs (ALIGN)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 98 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 17, 2026, 7:47 PM EDT
Completed Not applicable Interventional Results available

Improving Function in Older Veterans With Hospital-Associated Deconditioning

NCT02696382
View directory record Official record
Conditions
Frail Elderly, Homebound Persons
Interventions
Progressive High Intensity Therapy (PHIT), Usual Care (UC)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 99 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Oct 17, 2026, 7:47 PM EDT