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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: End of Life Communication Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations

NCT04612738
View directory record Official record
Conditions
Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness, Communication
Interventions
Hello (serious game), The Conversation Project (CP) Starter Kit, Table Topics (general conversation game)
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
79
States / cities
Athens, Alabama • Kingman, Arizona • Show Low, Arizona + 70 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional

An Educational Intervention to Improve Resident Comfort With Communication at the End of Life

NCT01150968
View directory record Official record
Conditions
End of Life Communication
Interventions
End of life education
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2011 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)

NCT04283994
View directory record Official record
Conditions
Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions
Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Improving Communication About Serious Illness

NCT01933789
View directory record Official record
Conditions
Critical Illness, Chronic Disease, Terminal Care, Palliative Care, Communication, Advance Care Planning, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, End Stage Liver Disease, Kidney Failure, Chronic
Interventions
Communication Feedback Form for Patients with Serious Illness
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
817 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
Renton, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers

NCT04994782
View directory record Official record
Conditions
Implantable Defibrillator User, Terminal Illness
Interventions
GAME-EOL
Behavioral
Lead sponsor
Debra Moser
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Jul 21, 2026, 7:42 PM EDT
Withdrawn Not applicable Interventional

Decision Aid Feasibility Trial for Families of Critically Ill Stroke Patients

NCT04143113
View directory record Official record
Conditions
Ischemic Stroke, Ischaemic Stroke With Coma, Intracerebral Hemorrhage, Hemorrhagic Stroke
Interventions
Decision Aid
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2021 · Synced Jul 21, 2026, 7:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

South Florida Residents Knowledge and Opinions on End-of-Life Issues

NCT01008241
View directory record Official record
Conditions
Death
Interventions
Paper questionnaire
Behavioral
Lead sponsor
Maria Isabel Fernandez
Other
Eligibility
18 Years and older
Enrollment
361 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Children's Books to Brochures for Safe Sleep and Infant Reading Education During Prenatal Care

NCT04031235
View directory record Official record
Conditions
Sudden Unexplained Infant Death, Child Rearing, Literacy
Interventions
Sleep Baby, Safe and Snug, Read Baby, Every Day
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
16 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2021 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeting Bias to Reduce Disparities in End of Life Care

NCT05165888
View directory record Official record
Conditions
Terminal Illness, Critical Illness
Interventions
Communication and Bias Mitigation Training, Communication skills training
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using a Nurse-Led Communication Strategy for Surrogates in the Intensive Care Unit

NCT03770481
View directory record Official record
Conditions
Communication Research
Interventions
nurse-led communication strategy
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)

NCT00106080
View directory record Official record
Conditions
Pulmonary Disease, COPD, Chronic Bronchitis, Emphysema
Interventions
Audit and Feedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care

NCT01775436
View directory record Official record
Conditions
HIV
Interventions
FAmily-CEntered Advance Care Planning, Healthy Living Control
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
5
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

End-of-Life Care for African Americans

NCT02320123
View directory record Official record
Conditions
Colonic Neoplasms, Breast Neoplasms, Lung Neoplasms
Interventions
Educational DVD
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Jul 21, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Study of The CKM JumpStart Tool

NCT05753020
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
CKM Jumpstart Tool
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
75 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Phase 1Phase 2 Interventional Results available

PRISM Race and Communication Pilot RCT

NCT04915079
View directory record Official record
Conditions
Discrimination, Racial, Communication, Chronic Illness, Bias, Racial
Interventions
Promoting Resilience in Stress Management (PRISM)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 21, 2026, 7:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Choice of Diction's Effect

NCT04896411
View directory record Official record
Conditions
Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
Interventions
Alternative phrasing for no code, Standard of care for no code
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Phase 3 Interventional

Improving Clinician Communication Skills (ICCS)

NCT00687349
View directory record Official record
Conditions
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure, End Stage Liver Disease
Interventions
Training Program Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
6,086 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
Charleston, South Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Advance Care Planning for Older Latinos With Chronic Illness

NCT06081660
View directory record Official record
Conditions
Patient Engagement, End of Life, Chronic Disease, Communication
Interventions
ACP-I Plan
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Serious Illness Communication Project

NCT01786811
View directory record Official record
Conditions
End of Life Care, Cancer
Interventions
Training
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
994 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2019 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Improving Patient Communication About SUDEP

NCT03502759
View directory record Official record
Conditions
SUDEP, Epilepsy
Interventions
CHICA SUDEP module
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
0 Years to 21 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Patient and Family Centered Care in Advanced Critical Illness

NCT01844492
View directory record Official record
Conditions
Anxiety, Depression
Interventions
The PARTNER Intervention, ICU Usual Care Control
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Jul 21, 2026, 7:42 PM EDT
Active, not recruiting Not applicable Interventional

Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication

NCT07147023
View directory record Official record
Conditions
Advanced Cancer, Cancer, End of Life
Interventions
LLM SIC Summary Email
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSDM: A Trial to Improve Communication and Shared Decision Making Using a Web-Based Tool

NCT02955563
View directory record Official record
Conditions
Intervention Compliance, Usability, Acceptability
Interventions
CSDM Web-Based Tool Intervention
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Jul 21, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Communicating About Choices in Transplantation

NCT01853007
View directory record Official record
Conditions
End Stage Renal Disease and Kidney Transplantation
Interventions
COACH Program
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Jul 21, 2026, 7:42 PM EDT