Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:47 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 976 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Endothelial Clear all

Conditions: Vascular Diseases
Interventions: Rhythmic Handgrip Exercise, Chronic Exercise Training; Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 90 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Peripheral Artery Disease, Claudication, Intermittent
Interventions: Passive calf muscle stretching device; Device
Lead sponsor: Penn State University; Other
Eligibility: 40 Years to 85 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Chronic Kidney Disease
Interventions: Sevelamer carbonate, Calcium acetate; Drug
Lead sponsor: Albany College of Pharmacy and Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Albany, New York

Conditions: Cardiovascular Disease
Interventions: Antioxidant cocktail, Biopsy, Placebo, NMD; 0.4mg sub-lingual nitroglycerin spray; Dietary Supplement · Other · Drug
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Secondary Pulmonary Arterial Hypertension
Interventions: Heart Catheterization; Procedure
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Endothelial Dysfunction
Interventions: Dietary nitrate in the form of beetroot juice for all participnats, Nature Made vitamin c 1000 mg, Placebo; Dietary Supplement
Lead sponsor: David Travis Thomas; Other
Eligibility: 50 Years to 70 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Lexington, Kentucky

Conditions: HIV, Cardiovascular Diseases, Atherosclerosis
Interventions: Pentoxifylline, Placebo; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Obesity, Pre-hypertension, Hypertension
Interventions: Resistance exercise training, Hypocaloric diet, Resistance exercise training & diet; Other
Lead sponsor: Florida State University; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Type 2 Diabetes
Interventions: Saxagliptin, Placebo; Drug
Lead sponsor: George Washington University; Other
Eligibility: 40 Years to 70 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Retinal Vein Occlusion, Macular Edema
Interventions: Anti-VEGF; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 323 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Obesity, Metabolic Syndrome
Interventions: Empagliflozin 25 MG, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Emotions, Endothelial Dysfunction
Interventions: Anger Induction, Depressed Mood Induction, Anxiety Induction, Neutral emotion task; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Type 1 Diabetes, Diabetic Kidney Disease, Cardiovascular Diseases, Endothelial Dysfunction, Insulin Sensitivity
Interventions: Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution, Placebo; Drug
Lead sponsor: Kalie Tommerdahl; Other
Eligibility: 12 Years to 25 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Aurora, Colorado • Seattle, Washington

Conditions: Chronic Kidney Disease
Interventions: Aerobic exercise training, Health Education; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 60 Years to 85 Years
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Boston, Massachusetts

Conditions: Endothelial Dysfunction
Interventions: Lansoprazole, Placebo; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Stanford, California

Conditions: Inflammation
Interventions: aldosterone, low or high sodium diet, placebo; Drug · Dietary Supplement
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Coronary Artery Disease
Interventions: Grape seed extract and ascorbic acid; Dietary Supplement
Lead sponsor: Boston University; Other
Eligibility: 21 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Kidney Disease, Cardiovascular Disease
Interventions: Lanthanum carbonate, placebo, Ascorbic Acid, Nitroglycerin, Flow-mediated dilation measurement, Aortic pulse-wave velocity, Endothelial cell collection; Drug · Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years to 79 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Hypertension (Without Type 2 Diabetes Mellitus), High Blood Pressure, Male, Female, Adult, Cognition, Endothelial Function (Reactive Hyperemia), Oxidative Stress, Diet, Overweight, Body Composition Measurement, Gut Microbiome, Arterial Stiffness, Caucasian Whites, Inflammation, Microvascular Function
Interventions: Wild Blueberry, Placebo; Dietary Supplement
Lead sponsor: Georgia State University; Other
Eligibility: 45 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Aging, Inflammation
Interventions: Typhoid Vaccine, Ascorbic Acid; Biological · Dietary Supplement
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Advanced Gastrointestinal Tumors
Interventions: TAS-102, CPT-11, Bevacizumab; Drug
Lead sponsor: Taiho Oncology, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 4
States / cities: Los Angeles, California • Chicago, Illinois • New York, New York + 1 more

Conditions: Wet Age-related Macular Degeneration
Interventions: Tarcocimab tedromer, Tabirafusp tedromer, Aflibercept; Drug
Lead sponsor: Kodiak Sciences Inc; Industry
Eligibility: 50 Years and older
Enrollment: 667 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 71
States / cities: Gilbert, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 66 more

Conditions: Central Nervous System
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Overweight, Obesity, Aging, Menopause
Interventions: 70 mL red beetroot juice, 70 mL red beetroot juice without nitrate, 70 mL placebo drink plus potassium nitrate, 70 mL placebo drink; Dietary Supplement
Lead sponsor: Colorado State University; Other
Eligibility: 40 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Fort Collins, Colorado

Search by objective public record fields.

Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS

Passive Calf Stretching Therapy in Peripheral Artery Disease

Effect of Phosphate Binders on Markers of Vascular Health in Chronic Kidney Disease Stages 3 and 4

Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)

Endothelial Cell Dysfunction in Pulmonary Hypertension

Nitrate and Vitamin C on Vascular Health Oxidative Stress

Evaluating the Effectiveness of Pentoxifylline at Improving Blood Vessel Function in HIV-infected People Not Receiving Antiretroviral Medications

Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure

Effect of Saxagliptin on EPCs as a Cellular Biomarker for Evaluating Endothelial Dysfunction in Early T2DM Patients

A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein Occlusion or Diabetic Macular Edema

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Study of the Effects of Negative Emotions on Endothelial Function

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Exercise Trial in Chronic Kidney Disease

Effect of Proton Pump Inhibitors on Endothelial Function

Studies on Aldosterone and Vascular Function

Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function

Phosphate Lowering in CKD Trial

Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation

A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

Investigating Endothelial Precursor Cells (EPCs)

Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances