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Showing 1–24 of 77 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Expressed Emotion Clear all
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health: Phase III

NCT03220204
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention, MI-based educational control condition
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2021 · Synced Jul 21, 2026, 10:07 PM EDT
Completed No phase listed Observational

MRI Study of Brain Activity and Risk for Depression in Adolescents

NCT00047944
View directory record Official record
Conditions
Involutional Depression, Anxiety Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
10 Years to 55 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Positive Emotional Processing: Exploring Novel Treatment Targets in Social Phobia

NCT02136212
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Approach-positive AAT, Control AAT
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 55 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)

NCT01250431
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
EFT (Emotional Freedom Techniques)
Behavioral
Lead sponsor
Soul Medicine Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.

NCT07361731
View directory record Official record
Conditions
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques, Opioid Craving, Recovery, Emotional Regulation, Positive and Negative Affect, Stress, Biofeedback
Interventions
Heart rate variability biofeedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

A Novel Social Emotional Learning Curriculum for Youth With Epilepsy

NCT06427967
View directory record Official record
Conditions
Epilepsy
Interventions
Project Dream Team
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
12 Years to 26 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mobile-Web Emotion Self-management Tool

NCT02346591
View directory record Official record
Conditions
Stress, Depression
Interventions
Jauntly, Online stress management information
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates

NCT05619419
View directory record Official record
Conditions
Meditation, Pain, Mindfulness, Affect, Emotion Regulation
Interventions
Mindfulness-enhanced positive affect induction, Breathing Meditation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 21, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)

NCT05942469
View directory record Official record
Conditions
Burnout, Burnout, Professional, Positive Affect, Depression, Anxiety, Compassion Fatigue, Job Stress
Interventions
FOREST
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Positive Attitudes on Behavior and Wellness

NCT04441632
View directory record Official record
Conditions
Burnout, Stress, Emotional
Interventions
Positive feedback
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Jul 21, 2026, 10:07 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

SAGE LEAF 2: An Online Program to Reduce Dementia Caregiver Burden

NCT06708182
View directory record Official record
Conditions
Caregiving Stress, Caregiver Burden
Interventions
SAGE LEAF Positive Emotion Skills Course
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

Researching Emotions And Cardiac Health (REACH): Phase II

NCT02938052
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
PP-based health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Helping Others Toward Positive Emotions in People With Heart Failure

NCT01275742
View directory record Official record
Conditions
Heart Failure
Interventions
Brief Cognitive Therapy Intervention
Behavioral
Lead sponsor
Rebecca L. Dekker, PhD, RN, APRN
Other
Eligibility
21 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Online Positive Emotion Skills Intervention for Symptoms of Depression

NCT01964820
View directory record Official record
Conditions
Depression, Psychological Stress, Affect
Interventions
Positive Affect Skills Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Boosting Emotions & Happiness in Outpatients Living With Diabetes

NCT02736084
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Positive Psychology
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Life Enhancing Activities for Family Caregivers (LEAF 2.0)

NCT03610698
View directory record Official record
Conditions
Caregivers
Interventions
LEAF Positive Emotion Intervention, Emotion Reporting Control Condition
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Researching Emotions And Cardiac Health

NCT02737761
View directory record Official record
Conditions
Congestive Heart Failure, Emotions, Patient Compliance
Interventions
Qualitative Interview and Adherence Measurements
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Jul 21, 2026, 10:07 PM EDT
Recruiting Phase 2 Interventional

Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression

NCT06263660
View directory record Official record
Conditions
Depression
Interventions
Keto-like supplement, Placebo
Dietary Supplement
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Mental Health and Well-Being Via Awe Walks

NCT03550144
View directory record Official record
Conditions
Awe, Compassion, Anxiety
Interventions
Awe Walk, Control Walk
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Spouses/Partners Expressing Their Thoughts After Transplant

NCT01061801
View directory record Official record
Conditions
Cancer, Hematopoietic Stem Cell Transplantation
Interventions
Emotional expression
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2010 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Family Promoting Positive Emotions Pilot Study

NCT05223842
View directory record Official record
Conditions
Depression, Anhedonia, Stress, Depressive Disorder, Behavioral Symptoms, Mood Disorders, Mental Disorder, Mood Disturbance
Interventions
Family Promoting Positive Emotions (F-PPE), Written Information
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
8 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Emotional Awareness and Expression Therapy (EAET) as a Novel Migraine Treatment

NCT05837650
View directory record Official record
Conditions
Migraine Disorders
Interventions
Emotional Awareness and Expression Therapy (EAET)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 21, 2026, 10:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Investigating the Neural Systems That Support the Reappraisal Tactics Leading to Positive Emotion

NCT04532242
View directory record Official record
Conditions
Behavior
Interventions
Cognitive reappraisal
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Jul 21, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating the Neural Systems That Support the Beneficial Effects of Positive Emotion on Stress Regulation

NCT04496258
View directory record Official record
Conditions
Behavior
Interventions
Positive Emotion Induction, Neutral Emotion Induction
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Jul 21, 2026, 10:07 PM EDT