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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fat Loss Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

NCT06129110
View directory record Official record
Conditions
Obesity, Insulin Sensitivity, Muscle Weakness, Adiposity, Insulin Resistance
Interventions
Diet Weight Loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Terminated Phase 4 Interventional

Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers

NCT04614233
View directory record Official record
Conditions
Overweight and Obesity
Interventions
RiduZone (90% OEA), Placebo
Dietary Supplement · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Two Exercise Programs on Obese Patients

NCT03980860
View directory record Official record
Conditions
Obesity, Hypertension
Interventions
Exercise Type
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition

NCT01423019
View directory record Official record
Conditions
Weight Loss
Interventions
Advantra Z, Advantra Z + Naringin + Hesperiden, Sugar pill
Dietary Supplement · Other
Lead sponsor
Integrative Health Technologies, Inc.
Network
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2012 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increased Dietary Protein and Meal Frequency Reduces Total and Abdominal Body Fat During Weight Maintenance and Weight Loss

NCT01749449
View directory record Official record
Conditions
Obesity
Interventions
protein and meal frequency
Other
Lead sponsor
Skidmore College
Other
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2012 · Synced Jun 11, 2026, 1:34 AM EDT
Active, not recruiting Not applicable Interventional Results available

Effect of Time-restricted Eating on Catecholamine-sensitivity of Adipose Tissue in Obese Adults

NCT04916730
View directory record Official record
Conditions
Obesity
Interventions
Standard of Care, Time Restricted Eating
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Recruiting Phase 1Phase 2 Interventional

Autologous Adipose Cells Therapy

NCT06869252
View directory record Official record
Conditions
Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines, Skin Elasticity, Hair Thinning, Skin Pigmentation, Skin Texture
Interventions
Autologous Adipose Cells Therapy
Biological
Lead sponsor
CERM INC.
Industry
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Lewes, Delaware • Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss in Adults Over 50 with Obesity

NCT04014296
View directory record Official record
Conditions
Obesity
Interventions
High Protein Diet, Resistance Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 20, 2024 · Synced Jun 11, 2026, 1:34 AM EDT
Active, not recruiting Phase 4 Interventional

GLP-1s to Enhance Lasting Optimal Weight

NCT06861439
View directory record Official record
Conditions
Obesity
Interventions
Tirzepatide
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change

NCT06325722
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Low-carbohydrate Diet, Low-fat Diet
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glucagon Like Peptide 1 (GLP-1) Booster™ RCT Study

NCT07141472
View directory record Official record
Conditions
Blood Sugar; High, Overweight and Obesity, Fat Loss, GLP-1, Glucagon
Interventions
GB, Placebo
Dietary Supplement
Lead sponsor
Lawry Han
Industry
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss

NCT00692731
View directory record Official record
Conditions
Overweight, Obesity
Interventions
500 mL/day of a beverage providing approximately 625 mg catechins, Control beverage matched for energy and caffeine content
Dietary Supplement · Other
Lead sponsor
Provident Clinical Research
Other
Eligibility
21 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
St. Petersburg, Florida • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Jun 11, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion

NCT07361874
View directory record Official record
Conditions
Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS), Subclinical Cushing's, Mild Autonomous Cortisol Excess
Interventions
Intervention 1: Adrenalectomy, Intervention 2: Semaglutide
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers

NCT03171415
View directory record Official record
Conditions
Obesity, Weight Loss, Overweight and Obesity
Interventions
RZL-012, Placebo
Drug
Lead sponsor
Raziel Therapeutics Ltd.
Industry
Eligibility
20 Years to 60 Years · Male only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Jun 11, 2026, 1:34 AM EDT
Recruiting Phase 2 Interventional

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

NCT06518837
View directory record Official record
Conditions
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Interventions
Tirzepatide
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Elizabeth, New Jersey • Hamilton, New Jersey • Livingston, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Factors Affecting Caloric Regulation in Human Feeding

NCT00108784
View directory record Official record
Conditions
Obesity
Interventions
Reduced-energy-density diet
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
20 Years to 60 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2010 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Including Almonds in a Weight Loss Trial

NCT02360787
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Energy restriction, Almonds (15% kcal/day)
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Framingham State Food Study

NCT02068885
View directory record Official record
Conditions
Obesity, Diabetes, Cardiovascular Disease
Interventions
Feeding study
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NCT06138821
View directory record Official record
Conditions
Obesity, Liver Diseases, Liver Fibrosis, Liver Fat, Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, MASLD, MASH, Weight Loss, Insulin Resistance, Insulin Sensitivity, Insulin Sensitivity/Resistance, Metabolic Disease, Diabetes, Diabetes Mellitus, Type 2, NASH With Fibrosis, Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Non-alcoholic Steatohepatitis
Interventions
ESG + lifestyle modification, Lifestyle modification
Device · Behavioral
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Completed No phase listed Interventional Results available

An Evaluation of the Effect of the Erchonia Laser for Non-invasive Reduction of Submental Fat

NCT05954065
View directory record Official record
Conditions
Weight Loss
Interventions
Erchonia CFL Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Harvey, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jun 11, 2026, 1:34 AM EDT
Not listed Not applicable Interventional

Weight Loss and Abdominal Fat Responses to Different Diet Compositions

NCT01034046
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolic Syndrome
Interventions
Low Carbohydrate Diet, Low Fat Diet
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 29, 2010 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity

NCT04731688
View directory record Official record
Conditions
Gestational Weight Gain, Obesity
Interventions
Weight Maintenance Group
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
San Luis Obispo, California • Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults

NCT03459703
View directory record Official record
Conditions
Obesity
Interventions
Early Time-Restricted Feeding, Control Schedule, Structured Weight Loss Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Jun 11, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Genetics, Metabolism and Weight Loss in Older, Obese Veterans

NCT00018330
View directory record Official record
Conditions
Obesity
Interventions
Weight Loss
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Jun 11, 2026, 1:34 AM EDT