Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 15, 2026, 5:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Fat Loss Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Two Exercise Programs on Obese Patients

NCT03980860
View directory record Official record
Conditions
Obesity, Hypertension
Interventions
Exercise Type
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 15, 2026, 5:50 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation

NCT06299098
View directory record Official record
Conditions
Obesity
Interventions
Trevogrumab-Part A, Trevogrumab-Part B and Part C, Garetosmab, Semaglutide, Matching Placebo-Part A, Matching Placebo-Trevogrumab, Matching Placebo-Garetosmab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,005 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
58
States / cities
Anniston, Alabama • Cullman, Alabama • Phoenix, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults

NCT03459703
View directory record Official record
Conditions
Obesity
Interventions
Early Time-Restricted Feeding, Control Schedule, Structured Weight Loss Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance

NCT00264251
View directory record Official record
Conditions
HIV Infections, Insulin Resistance, Obesity
Interventions
Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
Behavioral · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
20 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2007 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Progressive Metabolic Adaptations to Low Intensity Exercise Training and Weight Loss

NCT01452074
View directory record Official record
Conditions
Obesity
Interventions
Exercise Training, Weight Loss with continued Exercise Training
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 20, 2022 · Synced Sep 15, 2026, 5:50 PM EDT
Terminated No phase listed Interventional Results available

Vestibular Stimulation to Trigger Adipose Loss Clinical Trial

NCT03138369
View directory record Official record
Conditions
Obesity, Obesity, Abdominal, Metabolic Syndrome, Weight Loss
Interventions
Vestibular nerve stimulator, Sham vestibular stimulation
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 15, 2026, 5:50 PM EDT
Active, not recruiting Early Phase 1 Interventional Results available

Ruxolitinib for Cancer Cachexia

NCT04906746
View directory record Official record
Conditions
Stage IV Non-small Cell Lung Cancer, Cachexia
Interventions
Identify any dose-limiting toxicity (DLT) when ruxolitinib is administered to NSCLC cachexia patients.
Drug
Lead sponsor
Tu Dan
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 15, 2026, 5:50 PM EDT
Not listed Not applicable Interventional

Weight Loss and Abdominal Fat Responses to Different Diet Compositions

NCT01034046
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolic Syndrome
Interventions
Low Carbohydrate Diet, Low Fat Diet
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 29, 2010 · Synced Sep 15, 2026, 5:50 PM EDT
Recruiting Phase 2 Interventional

Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer

NCT06518837
View directory record Official record
Conditions
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Interventions
Tirzepatide
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Elizabeth, New Jersey • Hamilton, New Jersey • Livingston, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 15, 2026, 5:50 PM EDT
Completed No phase listed Observational

Assessment of Changes in Abdominal Fat

NCT00228579
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2020
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Calorie Deprivation on Adipose Tissue Distribution

NCT01658397
View directory record Official record
Conditions
Healthy
Interventions
Fasting
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

NCT03640286
View directory record Official record
Conditions
Obesity
Interventions
VeSTAL
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
La Jolla, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 2 Interventional Results available

Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults

NCT00119379
View directory record Official record
Conditions
HIV Infections, Lipodystrophy, Metabolic Diseases, Nutrition Disorders
Interventions
NucleomaxX, Tenofovir Disoproxil Fumarate
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Low Fat Versus Protein Sparing Diet for Weight Loss & Impact on Biomarkers Associated With Breast Cancer Risk

NCT01559194
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Low Fat Diet plus exercise, Low Carbohydrate diet + Exercise
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
30 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 15, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional

IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion

NCT07361874
View directory record Official record
Conditions
Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS), Subclinical Cushing's, Mild Autonomous Cortisol Excess
Interventions
Intervention 1: Adrenalectomy, Intervention 2: Semaglutide
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Re-energize With Nutrition, Exercise and Weight Loss

NCT00712127
View directory record Official record
Conditions
Obesity
Interventions
Diet and Exercise, Diet and Exercise-Delayed
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Capsinoids on Brown Adipose Tissue Activation in Obesity

NCT03110809
View directory record Official record
Conditions
Weight Loss
Interventions
Capsinoid, Placebo
Dietary Supplement
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Integrating the Genetic and Metabolic Faces of Obesity

NCT00285844
View directory record Official record
Conditions
Insulin Resistance, Obesity, Metabolic Syndrome
Interventions
weight loss, thiazolidinedione
Behavioral · Drug
Lead sponsor
Stanford University
Other
Eligibility
30 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 15, 2026, 5:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

NCT06129110
View directory record Official record
Conditions
Obesity, Insulin Sensitivity, Muscle Weakness, Adiposity, Insulin Resistance
Interventions
Diet Weight Loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Considering Patient Diet Preferences to Optimize Weight Loss

NCT01152359
View directory record Official record
Conditions
Obesity
Interventions
Choice, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 74 Years
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Treatment of Low Metabolic Rate Following Bariatric Surgery

NCT01596907
View directory record Official record
Conditions
Morbid Obesity
Interventions
Ephedrine sulfate with caffeine, cellulose
Drug
Lead sponsor
Oregon Weight Loss Surgery, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Beaverton, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Semaglutide Use in Elderly Obese Patients

NCT05302596
View directory record Official record
Conditions
Obesity, Aging
Interventions
Semaglutide Pen Injector
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly

NCT00779207
View directory record Official record
Conditions
Obesity
Interventions
weight loss and exercise, weight loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Sep 15, 2026, 5:50 PM EDT
Completed Phase 3 Interventional

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

NCT00070148
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
Interventions
Megestrol Acetate, Oxandrolone 20 mg
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
20
States / cities
Newark, Delaware • Miami Beach, Florida • Louisville, Kentucky + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Sep 15, 2026, 5:50 PM EDT