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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:31 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 99 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Fluid Management Clear all

Conditions: Pain Management, Postoperative Pain
Interventions: PCDD Generation 1 system; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Age Related Macular Degeneration
Interventions: Ranibizumab; Drug
Lead sponsor: Vitreous -Retina- Macula Consultants of New York; Other
Eligibility: 50 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy Volunteers
Interventions: TBPM-PI-HBr; Drug
Lead sponsor: Spero Therapeutics; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Pancreatitis, Acute
Interventions: Fluid administration; Other
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Heart Failure, Hypertension
Interventions: Not listed
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 21 Years to 90 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Riverside, California

Conditions: Acute Respiratory Failure, Intubation Complication, Hypotension on Induction
Interventions: Fluid Bolus, No Fluid Bolus; Drug · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 1,067 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 11
States / cities: Birmingham, Alabama • New Orleans, Louisiana • Burlington, Massachusetts + 7 more

Conditions: Sepsis, Systemic Inflammatory Response Syndrome
Interventions: Automated Pulse Pressure Variation; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: Up to 17 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Weight Gain
Interventions: Fluid intake app, Survey; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Healthy Volunteer
Interventions: Placebo, RO5508887; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Glendale, California

Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: CSF Diversion; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Respiratory Distress Syndrome, Adult
Interventions: NICOM-Guided Diuresis, Standard of Care; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Spinal Fusion
Interventions: Intervention, Control Group; Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Pancreatic Fluid Collections, Pancreatic Cyst
Interventions: Endoscopy-based (EUS-guided) interventions for pancreatic fluid collections, EUS of pancreatic cysts; Procedure
Lead sponsor: AdventHealth; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Respiratory Insufficiency
Interventions: Not listed
Lead sponsor: Smiths Medical, ASD, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Postoperative Complications
Interventions: Not listed
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Orange, California

Conditions: Respiratory Distress Syndrome, Newborn
Interventions: Fluid Management Intervention; Other
Lead sponsor: University of Oklahoma; Other
Eligibility: Up to 12 Hours
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 2
States / cities: New York, New York • Lawton, Oklahoma

Conditions: Severe Thermal Injury, Greater Than 20% TBSA
Interventions: Vitamin C, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Colonic Disease
Interventions: Feasibility Assessment; Device
Lead sponsor: WAE Medical; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: COVID
Interventions: CRI; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 70 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Pancreatic Cancer
Interventions: restrictive perioperative fluid management, Liberal perioperative fluid management; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Respiratory Failure, Intubation Complication
Interventions: intravenous crystalloid fluid, 500 mL; Drug
Lead sponsor: Louisiana State University Health Sciences Center in New Orleans; Other
Eligibility: 18 Years and older
Enrollment: 337 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 7
States / cities: Birmingham, Alabama • Jefferson, Louisiana • New Orleans, Louisiana + 4 more

Conditions: Nicotine Administration & Dosage, E-cigarettes, Vaping, E-Liquid, Tobacco Smoking
Interventions: JUUL, Tobacco; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Healthy Volunteer
Interventions: gantenerumab; Drug
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 40 Years to 70 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Lenexa, Kansas

Conditions: Postoperative Complication
Interventions: Goal-directed Therapy group; Procedure
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 334 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Orange, California

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PCDD Generation 1 Oral Liquid Acetaminophen Delivery Evaluation

A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study)

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Lactated Ringer's Versus Normal Saline for Acute Pancreatitis

Monitoring Subjects With Fluid-Management Issues In the Home Environment

Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation

PPV to Guide Fluid Management in the PICU

Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis

A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers

Cerebrospinal Fluid (CSF) Drainage Study

Non-invasive Fluid Management

Thromboelastography-Guided Fluid Management in Spinal Surgery

Registry of Pancreatic Fluid Collections and Pancreatic Cysts

Description of Fluid Balance in Patients With Acute Respiratory Failure

Evaluation of Goal-Directed Intraoperative Hemodynamic Optimization Protocol

Fluid Restriction in Respiratory Distress of the Newborn

Vitamin C for Severe Thermal Injuries

Performance of the Poseidon System for Fluid Management During Water-aided Colonoscopy

Compensatory Reserve Index (CRI) for Management of COVID-19

Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection

Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

A Study Investigating the Bioavailability of a High Concentration Liquid Formulation Versus a Reference Lyophilized Formulation of Gantenerumab in Healthy Volunteers

Goal Directed Fluid Management Based on Non-invasive Monitoring