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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fluid Management Clear all
Completed Not applicable Interventional

Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection

NCT01058746
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
restrictive perioperative fluid management, Liberal perioperative fluid management
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 7, 2026, 1:42 PM EDT
Withdrawn No phase listed Observational

Registry of Pancreatic Fluid Collections and Pancreatic Cysts

NCT02422095
View directory record Official record
Conditions
Pancreatic Fluid Collections, Pancreatic Cyst
Interventions
Endoscopy-based (EUS-guided) interventions for pancreatic fluid collections, EUS of pancreatic cysts
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational

The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol

NCT01714583
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome (ARDS)
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 25, 2012 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 2 Interventional Results available

Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee

NCT02003365
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
FX006 10 mg, FX006 40 mg, TCA IR 40 mg
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Paducah, Kentucky • Duncansville, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 7, 2026, 1:42 PM EDT
Active, not recruiting Not applicable Interventional

The ACES Study for Aseptic Pleural Effusion

NCT06210685
View directory record Official record
Conditions
Pleural Effusion
Interventions
Automatic Continuous Effusion Shunt implantation
Device
Lead sponsor
Pleural Dynamics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Hollywood, Florida • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 1 Interventional

A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma

NCT00221325
View directory record Official record
Conditions
Central Nervous System Lymphoma, Intraocular Lymphoma
Interventions
Intraventricular Rituximab Plus MTX
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
San Francisco, California • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2015 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Goal Directed Fluid Management Based on Non-invasive Monitoring

NCT01883752
View directory record Official record
Conditions
Postoperative Complication
Interventions
Goal-directed Therapy group
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hemodynamic Monitoring in Hepatopancreaticobiliary (HPB) Surgery

NCT03612687
View directory record Official record
Conditions
Cancer
Interventions
Minimally invasive hemodynamic monitoring
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 7, 2026, 1:42 PM EDT
Not listed Not applicable Interventional

Non-invasive Fluid Management

NCT02892799
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
NICOM-Guided Diuresis, Standard of Care
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational

Analgesic Efficacy of Orally Administered VTS-K for Pain Management

NCT04702555
View directory record Official record
Conditions
Pain, Acute
Interventions
VTS-K
Drug
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 110 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational Results available

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

NCT03192358
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Parkinson Disease, Dysphagia
Interventions
Videofluoroscopic Swallowing Examination, Tongue Strength Measurement
Diagnostic Test · Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

NCT05955586
View directory record Official record
Conditions
Healthy Volunteer
Interventions
SPR720
Drug
Lead sponsor
Spero Therapeutics
Industry
Eligibility
18 Years to 55 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 7, 2026, 1:42 PM EDT
Terminated Not applicable Interventional

RESIPI for Reducing Perioperative Major Adverse Cardiac Events

NCT03208023
View directory record Official record
Conditions
Inotropy, Fluid Management, Cardiac Event, Perioperative Cardiac Risk, Vascular Resistance, Hemodynamic Monitoring, Hemodynamic Management, Fluid Responsiveness
Interventions
RESIPI Management Strategy, No intervention
Procedure · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 7, 2026, 1:42 PM EDT
Terminated Phase 4 Interventional Results available

Double Blinded Randomized Control Trial of Types of IVF in Children With DKA

NCT03066440
View directory record Official record
Conditions
Diabetic Ketoacidosis
Interventions
Normal saline, Lactated Ringers
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
Up to 18 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis

NCT03759847
View directory record Official record
Conditions
Weight Gain
Interventions
Fluid intake app, Survey
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 3 Interventional Results available

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis

NCT03434028
View directory record Official record
Conditions
Septic Shock
Interventions
Early Vasopressors, Early Fluids
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,563 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
50
States / cities
Tucson, Arizona • Fresno, California • Los Angeles, California + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational

Thromboelastography-Guided Fluid Management in Spinal Surgery

NCT03999086
View directory record Official record
Conditions
Spinal Fusion
Interventions
Intervention, Control Group
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 4 Interventional

Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation

NCT03787732
View directory record Official record
Conditions
Acute Respiratory Failure, Intubation Complication, Hypotension on Induction
Interventions
Fluid Bolus, No Fluid Bolus
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
11
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Burlington, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Phase 4 Interventional Results available

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

NCT01495221
View directory record Official record
Conditions
AMD (With Persistent or Recurrent Fluid Despite Monthly Intravitreal Anti-VEGF Therapy)
Interventions
Alfilbercept
Drug
Lead sponsor
Vitreous -Retina- Macula Consultants of New York
Other
Eligibility
50 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Not applicable Interventional

Use of Point-of-Care Ultrasound (POCUS) to Reduce Hospital Length of Stay in Patients With Heart Failure ( POCUSHF )

NCT06965712
View directory record Official record
Conditions
Heart Failure, Decompensated Heart Failure, Hospital Length of Stay
Interventions
Point-of-Care Ultrasound (POCUS)
Device
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 7, 2026, 1:42 PM EDT
Completed Not applicable Interventional Results available

PPV to Guide Fluid Management in the PICU

NCT02308371
View directory record Official record
Conditions
Sepsis, Systemic Inflammatory Response Syndrome
Interventions
Automated Pulse Pressure Variation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 1, 2017 · Synced Sep 7, 2026, 1:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Aricept on Biomarkers (Acetylcholine, sAPP Alpha) In Cerebrospinal Fluid

NCT00987220
View directory record Official record
Conditions
Alzheimer's Disease, Dementia
Interventions
Placebo, donepezil (Aricept)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 13, 2011 · Synced Sep 7, 2026, 1:42 PM EDT
Recruiting Phase 2Phase 3 Interventional

Surviving PEA in Roanoke (SPEAR) Study

NCT05283850
View directory record Official record
Conditions
Cardiac Arrest, Pulseless Electrical Activity
Interventions
High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy
Drug
Lead sponsor
Carol Bernier
Other
Eligibility
18 Years and older
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Sep 7, 2026, 1:42 PM EDT
Withdrawn Not applicable Interventional

Intraoperative Goal-directed Fluid Management

NCT00554944
View directory record Official record
Conditions
Obesity, Abdominal Surgery, Hysterectomy, Genital Prolapse
Interventions
Esophageal probe
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2017 · Synced Sep 7, 2026, 1:42 PM EDT