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Showing 25–39 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Fluid Resuscitation Clear all
Completed No phase listed Observational Results available

Optimal Fluid Resuscitation for Trauma Patients

NCT00527098
View directory record Official record
Conditions
Trauma
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Sep 24, 2026, 8:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

I USE LR in the ED

NCT03807648
View directory record Official record
Conditions
Kidney Injury
Interventions
Data Inclusion
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Sep 24, 2026, 8:23 AM EDT
Terminated Phase 1 Interventional Results available

Oral Rehydration Therapy in Burn Patients

NCT02124265
View directory record Official record
Conditions
Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface, Burn Any Degree Involving 40-49 Percent of Body Surface, Burn Any Degree Involving 50-59 Percent of Body Surface, Burn Any Degree Involving 60-65 Percent of Body Surface, Fluid Resuscitation
Interventions
CeraLyte 90
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Phase 3 Interventional Results available

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis

NCT03434028
View directory record Official record
Conditions
Septic Shock
Interventions
Early Vasopressors, Early Fluids
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,563 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
50
States / cities
Tucson, Arizona • Fresno, California • Los Angeles, California + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Not applicable Interventional

Precision Resuscitation With Crystalloids in Sepsis

NCT06253585
View directory record Official record
Conditions
Sepsis
Interventions
Algorithm Alarm- Crystalloids, Standard of Care
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
2,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
7
States / cities
Atlanta, Georgia • Decatur, Georgia • Johns Creek, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 24, 2026, 8:23 AM EDT
Not listed Not applicable Interventional

De-resuscitation Informed by Ultrasound for Patients With Sepsis

NCT04921319
View directory record Official record
Conditions
Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Interventions
VExUS score
Diagnostic Test
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Phase 4 Interventional Results available

Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation

NCT03026777
View directory record Official record
Conditions
Acute Respiratory Failure, Intubation Complication
Interventions
intravenous crystalloid fluid, 500 mL
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
7
States / cities
Birmingham, Alabama • Jefferson, Louisiana • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 24, 2026, 8:23 AM EDT
Completed No phase listed Observational

Evaluation of Fluid Volume in Patients With Refractory Hypotension (Fresh-ER)

NCT05101031
View directory record Official record
Conditions
Undifferentated Shock
Interventions
Starling SV
Device
Lead sponsor
Ivor Douglas
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 24, 2026, 8:23 AM EDT
Not listed Phase 2 Interventional

The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy

NCT01428050
View directory record Official record
Conditions
Pancreaticoduodenectomy
Interventions
3% NaCl Solution, Lactated Ringers Solution
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Sep 24, 2026, 8:23 AM EDT
Recruiting Not applicable Interventional

Stroke Volume-based Fluid Resuscitation in AP

NCT07756476
View directory record Official record
Conditions
Acute Pancreatitis (AP)
Interventions
Lactated Ringer's, Lactated Ringers Stroke Volume Based Dosing
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 24, 2026, 8:23 AM EDT
Terminated Not applicable Interventional Results available

Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)

NCT01128413
View directory record Official record
Conditions
Shock
Interventions
Cheetah NICOM® PLRT, USCOM ® (Ultrasound Cardiac Output Monitor), Inferior Vena Cava (IVC) Ultrasound Collapsibility, CURVES Questionnaire, Lactate Clearance, 500ml Normal Saline Bolus, Clinician Discretion Intravenous Fluid Management
Device · Behavioral · Biological
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Device for Rapid Fluid Administration

NCT03074682
View directory record Official record
Conditions
Device Related Sepsis
Interventions
Lifeflow, Push/Pull, Pressure Bag
Device
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Phase 2 Interventional Results available

Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma

NCT01411852
View directory record Official record
Conditions
Blunt Trauma, Penetrating Wound, Hemorrhagic Shock
Interventions
0.9% Sodium Chloride 250 mL bolus, 0.9% Sodium Chloride 2000 mL bolus
Drug
Lead sponsor
University of Washington
Other
Eligibility
15 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Birmingham, Alabama • Portland, Oregon • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Sep 24, 2026, 8:23 AM EDT
Recruiting Not applicable Interventional

Effect of Giving Reduced Fluid in Children After Trauma

NCT04201704
View directory record Official record
Conditions
Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries
Interventions
Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume, Platelets volume
Other
Lead sponsor
Columbia University
Other
Eligibility
6 Months to 15 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Buffalo, New York • New York, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 24, 2026, 8:23 AM EDT
Completed Not applicable Interventional

Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients

NCT01270854
View directory record Official record
Conditions
Wounds and Injuries, Multiple Trauma, Disorder of Fluid Balance
Interventions
Plasmalyte A, Normal Saline
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 24, 2026, 8:23 AM EDT