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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:46 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 396 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Foot Ulcers, Diabetic Clear all

Conditions: Diabetic Foot Ulcers
Interventions: Unite Biomatrix, Saline and Gauze; Device · Other
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 11
States / cities: San Diego, California • Miami, Florida • Evans, Georgia + 5 more

Conditions: Wound Healing, Diabetic Foot, Chronic Foot Ulcer, Foot Ulcer
Interventions: Endoform™ Antibacterial, Endoform™ Natural, Symphony™; Device
Lead sponsor: Aroa Biosurgery Limited; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 4
States / cities: Hollywood, Florida • Miami, Florida • Salem, Virginia + 1 more

Conditions: Diabetic Foot Ulcers (DFUs), Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions: Miro3D Wound Matrix, Standard of Care (SOC); Device · Other
Lead sponsor: Reprise Biomedical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 3
States / cities: Coconut Creek, Florida • Tamarac, Florida • New York, New York

Conditions: Diabetic Foot, Lower Extremity Wound
Interventions: Matrion, Conventional Care Wound Management; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 8
States / cities: Tucson, Arizona • Carmichael, California • Fresno, California + 5 more

Conditions: Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
Interventions: Total Contact Soft Cast, Cam Boot; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Diabetic Foot Ulcer, DFU, Diabetic Foot Ulcer (DFU), Foot Ulcer Due to Type 1 Diabetes Mellitus, Foot Ulcer Due to Type 2 Diabetes Mellitus, Ulcer, Ulcer Foot
Interventions: Activate™ Matrix, AmnioDefend™ FT Matrix, Palisade™ DM Matrix, Enclose™ TL Matrix, Sentry™ SL Matrix, Shelter™ DM Matrix + SOC; Other
Lead sponsor: Sequence LifeScience, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Diabetic Foot Infection, Diabetic Foot
Interventions: Topical Pravibismane, Standard of Care; Drug · Other
Lead sponsor: Microbion Corporation; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 7
States / cities: Fresno, California • Dallas, Texas • McAllen, Texas + 1 more

Conditions: Diabetic Foot Ulcers
Interventions: ofloxacin, MSI-78; Drug
Lead sponsor: Abeona Therapeutics, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 342 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence, Burns, Other Types of Chronic Non Healing Wounds
Interventions: NPWT; Device
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 50,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Diabetic Foot, Foot Ulcer; Diabetic
Interventions: Offloading, Dressing Application; Device · Procedure
Lead sponsor: Lower Extremity Institute for Research and Therapy; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2015
U.S. locations: 3
States / cities: Canfield, Ohio • Danville, Virginia • Troutville, Virginia

Conditions: Foot Ulcer, Diabetic, Infection
Interventions: Gentamicin Collagen sponge, Placebo; Drug · Other
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 524 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Anniston, Alabama • Las Vegas, Nevada

Conditions: Peripheral Arterial Disease, Diabetic Foot, Diabetes Mellitus
Interventions: ABI/WIFI scoring; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Chronic Wound, Burn Wound, Diabetic Foot Ulcers, Pressure Ulcers, Venous Leg Ulcers, Chronic, Wound
Interventions: Epiceram Skin Barrier Function, Vaseline Petroleum Jelly; Device · Biological
Lead sponsor: Sashwati Roy; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2034
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania

Conditions: Lower Extremity Chronic Ulcers in Diabetics
Interventions: CureXcell®, Sham injection; Biological
Lead sponsor: Macrocure Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 31
States / cities: Glendale, Arizona • Mesa, Arizona • Phoenix, Arizona + 28 more

Conditions: Diabetic Neuropathies, Painful, Diabetic Foot, Diabetic Peripheral Neuropathy
Interventions: Capsaicin Palmitate, Placebo; Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 25 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Foot Ulcer, Diabetic
Interventions: Daily use of podimetrics smart-foot mat; Device
Lead sponsor: Podimetrics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 8
States / cities: Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 5 more

Conditions: Diabetic Foot Ulcer
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Diabetic Foot
Interventions: Not listed
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Diabetic Foot Ulcer
Interventions: NOX1416 and SOC, SOC (Standard of care); Drug · Procedure
Lead sponsor: NOxy Health Products, LLC; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 13
States / cities: Phoenix, Arizona • Tucson, Arizona • Coral Gables, Florida + 9 more

Conditions: Foot Ulcer, Diabetic, Diabetes Complications
Interventions: MRE0094; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 322 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 63
States / cities: Montgomery, Alabama • Bullhead City, Arizona • Phoenix, Arizona + 56 more

Conditions: Diabetes, Foot Ulcer
Interventions: INTEGRA™ Flowable Matrix (Collagen); Drug
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Foot Ulcer, Diabetic
Interventions: Wound Dressing; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 6
States / cities: Montgomery, Alabama • Castro Valley, California • Bay Pines, Florida + 3 more

Conditions: Diabetic Foot Ulcers
Interventions: Cardinal Pro +Simultaneous Irrigation (NPWTi), Cardinal Pro (NPWT) Therapy; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 21 Years to 89 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Venous Leg Ulcer, Diabetic Foot Ulcer
Interventions: EscharEx (EX-02 formulation); Drug
Lead sponsor: MediWound Ltd; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Tamarac, Florida • Las Vegas, Nevada • Chapel Hill, North Carolina

Search by objective public record fields.

The Mechanism of Action of the Unite Biomatrix in Diabetic Foot Ulcer

Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers

Total Contact Soft Cast in Diabetic Foot Ulcers

Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy

Multi-center Study to Assess Safety, Tolerability and Efficacy of Topical Pravibismane in Moderate DFI Patients

MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers

Negative Pressure Wound Therapy Registry

Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers

Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers

Implementation of ABI and WIfI in Rural Health Clinics

Wound Healing Endpoint and Recurrence

Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes

Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain

In-Home Assessment of a Smart Foot Mat for Prevention of Diabetic Foot Ulcers

Study to Evaluate Bacterial Activity That Drives the Progression of Clinical Infection

Study of Subjects With Diabetic Foot Ulcer (DFU)

NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers

Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers

Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers

A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

Negative Pressure Wound Therapy as a Drug Delivery System

A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers