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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 396 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Foot Ulcers, Diabetic Clear all

Conditions: Wounds and Injuries
Interventions: Allevyn Life, Foam dressing with an integrated adhesive border; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 65 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Tustin, California • Wichita, Kansas • McAllen, Texas

Conditions: Wound, Venous Leg Ulcer, Diabetic Foot Ulcer, Arterial Leg Ulcer
Interventions: geko device; Device
Lead sponsor: Firstkind Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetic Foot Ulcer
Interventions: Removable cam walker boot, Counseling; Device · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • Hines, Illinois

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Surgical Wound Dehiscence, Traumatic Wounds
Interventions: Study Device Debridement, SOC Debridement; Device
Lead sponsor: Medaxis, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Diabetic Foot Ulcers
Interventions: Nexagon® Low Dose, Nexagon® Medium Dose, Nexagon® High Dose, Nexagon® vehicle; Drug
Lead sponsor: OcuNexus Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 9
States / cities: Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 6 more

Conditions: Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
Interventions: Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU, Standard of Care - VLU, AM/Single - VLU, AM/Double - VLU; Other
Lead sponsor: C5 Biomedical; Industry
Eligibility: 18 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Metairie, Louisiana

Conditions: Diabetic Foot Ulcer
Interventions: doxycycline, placebo gel; Drug
Lead sponsor: NanoSHIFT LLC; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Diabetic Foot Ulcer, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Neuroischemic Foot Ulcer, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer), Chronic Wound Care
Interventions: Platelet Rich Plasma; Device
Lead sponsor: Estar Medical dba Medical Technologies, LTD; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Corpus Christi, Texas

Conditions: Diabetic Foot Ulcer
Interventions: Derm-Maxx; Other
Lead sponsor: Capsicure, LLC; Network
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 11
States / cities: Athens, Alabama • Encino, California • Hollywood, Florida + 8 more

Conditions: Foot Ulcer, Foot Ulcer, Diabetic
Interventions: Ulcer Measurement Software; Device
Lead sponsor: Linnea Polgreen; Other
Eligibility: 21 Years to 100 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Diabetic Foot Ulcer
Interventions: Corlicyte; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Diabetic Foot Ulcer
Interventions: 12-week home based exercise, 12-week standard of care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pressure Ulcer
Interventions: Adipose-derived stromal cells, Adipose-derived stromal cells; Biological · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Diabetes Mellitus, Foot Ulcer, Ulcer, Diabetic Foot Ulcer, Wound, Wound Heal
Interventions: No interventions; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 4
States / cities: Indianapolis, Indiana • Columbus, Ohio

Conditions: Chronic Diabetic Foot Ulcers
Interventions: Extracorporeal Shockwaves; Device
Lead sponsor: Tissue Regeneration Technologies; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 5
States / cities: Washington D.C., District of Columbia • The Bronx, New York • Akron, Ohio + 2 more

Conditions: Diabetic Foot Ulcer
Interventions: SOC and Advanced Bioengineered Skin Substitute, SOC and Active Comparator; Device · Other
Lead sponsor: Encoll Corp; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 3
States / cities: Los Angeles, California • South Miami, Florida • Salem, Virginia

Conditions: Diabetic Foot Ulcer, Infection
Interventions: PluroGel N, PluroGel; Drug
Lead sponsor: PluroGen Therapeutics, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 15
States / cities: Phoenix, Arizona • Los Angeles, California • Oakland, California + 8 more

Conditions: Foot Ulcer, Diabetic
Interventions: Transcutaneous O2 device; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 89 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Diabetic Foot, Diabetic Peripheral Neuropathy
Interventions: Orpyx SI® Sensory Insole System; Device
Lead sponsor: Orpyx Medical Technologies Inc.; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Circleville, Ohio

Conditions: Diabetes Mellitus, Foot Ulcer
Interventions: RCW design form; Device
Lead sponsor: Rosalind Franklin University of Medicine and Science; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: North Chicago, Illinois

Conditions: Foot Ulcer, Diabetic
Interventions: test pressure alternating shoes; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Non-Diabetic Patients, Wound Leg, Chronic Ulcer Leg/Foot
Interventions: Not listed
Lead sponsor: Chandan Sen; Other
Eligibility: 30 Years and older
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2023
U.S. locations: 3
States / cities: Indianapolis, Indiana • Columbus, Ohio

Conditions: Diabetic Foot Ulcer
Interventions: Spatial Frequency Domain Imaging (SFDI); Device
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetic Foot Ulcer
Interventions: Amnio-Maxx; Other
Lead sponsor: Capsicure, LLC; Network
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 12
States / cities: Athens, Alabama • San Diego, California • Coral Gables, Florida + 9 more

Search by objective public record fields.

Managing Wounds With Allevyn Life in a Home Health Care Environment

Geko™ Cross Therapy Registry - Wound

Orthotic Treatment of Diabetic Foot Ulcers

Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center

A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers

Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Diabetic Foot Ulcer Imaging- Study 2

PHASE 1, OPEN-LABEL SAFETY STUDY OF UMBILICAL CORD LINING MESENCHYMAL STEM CELLS (CORLICYTE®) TO HEAL CHRONIC DIABETIC FOOT ULCERS

At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers

Adipose-Derived Stromal Cells (ASC's) for Pressure Ulcers

miR-200b & miR-21 in Diabetic Wounds

Safety & Efficacy Study for the Use of Extracorporeal Shockwaves in the Treatment of Diabetic Foot Ulcers

Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers

Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers

Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers

Monitoring Physiologic Parameters in Individuals With Diabetic Peripheral Neuropathy

Impact of Removable Cast Walker Design on Usability for Patients With Diabetic Foot Ulcers

Pressure Alternating Shoes

Role of Tissue Oxygenation and the miR-210 Gene In Wound Healing

Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing

Amnio-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone